PKG

Protein list:

MAP2K7 TNF PPP2R5D MAP3K9 TRAF1 RAC3 FASLG CASP2 BIRC3 FAS PPM1A CASP8 PTPA RAC2 DAXX MAP3K8 NEK2 RIPK2 MAP3K4 CRADD MAPK1 MTA1 SRXN1 MAPK12 AK2 MAPK13 TRIM21 UBB MAPK11 ZYX HLCS HCLS1 ASAP3 RUVBL2 MAPK3 EXOSC5 SAFB2 MAP3K20 WDR62 IRS1 FADD MAPK10 MAP3K13 MAP3K5 MAPK9 JUN TRIB3 RPL30 BCL10 BRAF ALK HSP90AA1 LRRK2 MAP2K4 HSP90AB1 DUSP19 HSCB PIK3R1 LPXN GADD45B MAPK8 MRPL16 CYFIP2 ATP1A1 ACSL4 GTF3C3 FKBP4 PTGES3 PFDN6 ATP5PO FKBP8 PRMT5 RAB5C PRKCSH YTHDF2 RANBP2 DCAF7 AHSA1 CPVL ATP5PD LONP1 NDUFS3 SEC22B ALDH3A2 ZAK ANXA5 CACYBP CANX NDUFA4 NRAS VRK2 DDB1 RAB7A MAPK8IP3 FKBP5 SDF2L1 WDR6 XPO1 MAP3K11 PFKL MMS19 UBR5 ERC1 GLUD1 HAX1 TRABD ST13 SH3RF3 SUGT1 ATF4 MAP3K12 MRPS23 ATP5MF AKAP8L CAD MRPL49 PRKDC POLR2E MTR STUB1 ZDHHC17 CALU SEC16A TNFAIP8L1 RTCB MAP1B AIP SLC1A5 ATP2A2 MAPK14 DYNC1H1 DNAJB1 MAPK8IP2 ILVBL CLPB CNP MAPT MAP3K3 LPCAT1 SDHB NUP188 DNAJC10 PGRMC1 GCN1 ACSL3 RCN2 TUBG1 NR2C2 MAP3K7 FLNA MAP3K2 MAP3K1 ARR3 GSK3B CDC42 SH3RF1 MAPK8IP1 TNFRSF1A TNFRSF1B RAC1 RIPK1 GRB2 TRAF2 TRADD MAP3K10 TAOK2

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

PKG Score Threshold: 0.8

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Filter Table:

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
ACSL3	ACSL4	◼ PHYSICAL_INTERACTION			0.93	0.93	HIPPIE	22939629 26496610
AHSA1	HSP90AB1	◼ POST_TRANSLATIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	16696853 20618441
AHSA1	FKBP4	◼ PHYSICAL_INTERACTION			0.84	0.84	HIPPIE	25036637 22504172
AHSA1	HSP90AB1	◼ PHYSICAL_INTERACTION			962.0	0.96	STRING	36370105
AHSA1	HSP90AA1	◼ PHYSICAL_INTERACTION			969.0	0.96	STRING	36370105
AHSA1	HSP90AA1	◼ POST_TRANSLATIONAL_REGULATION	✅	+	16.0	1.0	Omnipath	25036637 16696853 17145710 19875381 12604615 24462205 26693507 26804907 22315411 12504007 20226818 20159553 22504172
AIP	HSP90AA1	◼ PHYSICAL_INTERACTION			834.0	0.83	STRING	36370105
ALK	MAP3K3	◼ PHYSICAL_INTERACTION			2.0	0.8	intact	14743216 5216883
ALK	GRB2	◼ PHYSICAL_INTERACTION			840.0	0.84	STRING	36370105
ATF4	TRIB3	◼ PHYSICAL_INTERACTION			0.89	0.89	HuRI	32296183

Showing 1 to 10 of 661 entries