PKG

Protein list:

YES1 FYN ASAP3 CTTN MAPK14 GNAO1 VAV2 SMAD4 NUDT4 EPHA2 G3BP1 GPC1 EPHA1 NPM1 UBB EPHA4 FZD2 MAPK11 PAK4 GIT2 RAC1 PLCG1 EFNA1 ARHGEF7 GNG2 EPHB1 FZD3 PDGFD TRIM29 PXN GSN ENO1 EPHB2 RGS1 FZD6 GAB1 S100A11 NUDT4B RAP1A BMX YWHAH HLCS CTNND1 TBC1D22A CDC42 UBTD2 SRXN1 HSPA8 PTK2B WNT6 GNAI3 EFNB1 PDGFB GNB1 SLA HSPB1 GNAZ MAPK1 RHOA PKM TXN WNT11 WNT5A GNAI1 WNT4 TDGF1 S1PR1 MBNL3 TRPV6 RAPGEF1 NCK2 RRAS MSN PAK1 RELA NCK1 YWHAZ EPHA3 PRKAR1A EGF FER CDK4 KRAS NRAS HRAS ALOX5 ZNF438 HASPIN CCNL2 TSHZ1 SETD1B RASA1 CYSRT1 KSR1 CSF1R FHOD3 FGR SAMD11 SOCS7 SF3A1 WIPF1 AFDN SMN1 DBN1 SSBP3 PEAR1 MADD IKZF3 BCORL1 BSN KCNA5 ESR1 SHTN1 PDE4DIP EIF4EBP1 TENM1 BECN1 PRKD1 HOXB5 FGFR1 TEX13A TIAM1 AMOTL2 C1QL4 CAMSAP3 EGFR CLDN4 PER1 KIT CDCP1 DOK1 ASAP2 IRS2 R3HDM1 RAB27A KMT2B SF3A2 FAM120C MYPN KHDRBS1 ZFC3H1 CCT2 HNRNPCL1 TRAF6 SKAP2 SH3GLB2 SOX2 RL2 NIF3L1 SPRR2A SNRPN PICK1 CRKL ADAM15 PRUNE2 MCM3AP PIM3 GRIN2B POF1B CDH1 NUTM2D PECAM1 OLIG1 MED21 TMEM185A ARHGEF5 CEP57L1 ASXL3 MBNL1 FAS JAKMIP1 SOCS1 CDK12 ZBTB21 KIFAP3 MAMLD1 ANKRD55 PARK2 IRS4 SHC1 PLEKHN1 SLC39A5 ACSL3 IFT52 PRRT4 DTX3 CCR1 SLC25A11 ZC2HC1A HDAC6 NUTM2E TSGA10IP NPHS1 IQGAP3 KIF26A SLC9A3R1 DOK2 ATF5 EPPK1 DHX15 YAP1 CHERP HSP90AA4P SLC25A41 BCLAF1 SYT6 LCK FUNDC1 BCAR1 SERPINB4 EFNB2 CDC37 HSP90AB4P FLT3 GRB2 ADAM10 HSP90AB1 SNRPB THAP1 HSP90AB3P HSP90AA1 RBM17 AR CD46 GAS8 SOCS3 ECM1 HNRNPC ERH CDK1 CCT3 RPL10

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

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PKG Score Threshold: 0.8

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
ADAM10	CDH1	◼ CLEAVAGE	✅		2.0	0.8	Reactome	18434311 15958533
AMOTL2	YAP1	◼ PHYSICAL_INTERACTION			874.0	0.87	STRING	36370105
AR	YWHAH	◼ PHYSICAL_INTERACTION			2.0	0.8	intact	19996220 8009645
AR	KRAS	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	8423674 24172884
AR	TXN	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	18945670 12463425
AR	IRS2	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	19318566 20610535
AR	PRKD1	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	20610535 18602367
AR	MAPK1	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	14619959 20610535
AR	GSN	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	20610535 18673534
AR	KHDRBS1	◼ TRANSCRIPTIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	18273831 20610535

Showing 1 to 10 of 763 entries