Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DVL2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
DVL2 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
DVL2 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
DVL2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DVL2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
DVL2 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
KIF4A KIF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10747093 10804209
AAK1 REPS1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
AP1B1 CLTA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8909539 11050117
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
GRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
AP2A2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A1 DNAJC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
AP2A1 MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
AP2A1 WNT5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2A1 VLDLR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17452316 18039658
AP2A1 FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2A2 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A1 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2A2 WNT5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2A2 VLDLR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17452316 18039658
AP2A2 FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2A2 MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A2 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
MAPK1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
GRB2 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
NECAP2 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
WNT5A AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2B1 VLDLR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17452316 18039658
AP2B1 FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2B1 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
AP2B1 DNAJC5 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
WNT5A AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
MAPK1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
GRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
VLDLR AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17452316 18039658
AP2M1 FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
MAPK1 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
GRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
WNT5A AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 VLDLR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17452316 18039658
AP2S1 FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 DNAJC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
AP2S1 CD74 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15749704 15911768
PPP2CA BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11593413
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
CBL SH3GL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11894095 16713569
CD4 HLA-DRA â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CD4 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DRA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
CD4 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DPA1 CD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12899833 16189514
HLA-DRA CD74 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
CD74 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218024 16242130
CLTA MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
CLTA VLDLR â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17452316 18039658
CLTB PQBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WNT5A CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
VLDLR CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17452316 18039658
MAPK1 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
CLTC FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
PICALM CLTCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16491119 10436022
NUMB DNAJC5 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
EGF EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24269888 25728925
EGF SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19531499 17673906
GRB2 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NUMB EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221644 9303539
ITSN1 EPS15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211195 10064583
STON2 EPS15L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6179743 18200045
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
PPP2R1A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
HLA-DQA2 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA1 HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DPA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
SH3GL2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HLA-DRA HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DQA2 HLA-DQA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
HLA-DRA HLA-DQA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
MAPK1 L1CAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
MAPK1 L1CAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17151951 21080252
MAPK1 SH3GL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
PPIH ZMAT2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
REPS1 STON2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6179743 18200045
UBQLN2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
AP2S1 NECAP2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
AAK1 AP2M1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 11877461
EPS15 NECP2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19380743
AP1B1 AP2A2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
CLTCL1 PICALM â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
AP2A1 AP2S1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
AP2S1 FCHO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2B1 FCHO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
RUN3A AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A EPS15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A AP2B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A REPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A AAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A NECP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A EP15R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A ITSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A RBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUN3A AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARFG1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NECP2 ITSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
GPBL1 AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP2A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPBL1 AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2B1 EP15R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
AP2S1 EP15R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AAGAB CO057 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 CO057 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AMPH AAGAB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RBP1 AAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 AAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
REPS1 AAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AMPH AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AMPH AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2A2 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
CFTR AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 17110338
AP2A1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26344197
NUMB AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 23211419
EGFR AP1B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24189400 24797263
ARRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
VCAM1 AP2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 AP2B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
NUMB AP2B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23211419 34079125
AP2B1 BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
AP2B1 STON2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
AP2B1 REPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
VCAM1 AP2M1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 AP2S1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AP2S1 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 REPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 STON2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 RBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 ITSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARRB2 DIEXF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RBP1 BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
REPS1 BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NTRK1 CBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21570973 25921289
NUMB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 25754235
VCAM1 EPS15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 PPIH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 STON2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AP2A1 AP2B1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
AP1G1 AP2M1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
NECP2 AP1G1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14665628 26186194 33961781
NECP2 AP1B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NECP2 AP2S1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NECP2 AP2A2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NECP2 AP2A1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AP2A1 AMPH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 12057195
EPS15 AP1B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 12538641 19380743
AP2A1 RBP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 31980649 10764745
EGFR AP2S1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24189400 25754235 24797263
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
EGFR EPHA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657067 24797263
RNF11 EPS15 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14755250 24377927 23222715
AP1G1 CLTC â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AP1B1 AP2S1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ITSN1 AP2A1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28484035 32203420
EPS15 STON2 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 6179743 18200045
ESR1 PQBP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
AP2M1 BMP2K â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HDAC6 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
AP2M1 REPS1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
AAGAB AP2A1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 31353312
AP1B1 ARRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11877451 10097102 12070169
EGFR AP2A2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31959764 24797263 23956138 8548289 24189400
EGFR AP2B1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24189400 24797263 23956138 7534311
AP2B1 AP2M1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CBL EPHA2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
AP2A1 NUMB â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
RBP1 NUMB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12775724 23211419
EPS15L1 ITSN1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
MAPK1 SHC1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
BCAR1 GRB2 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
BMP2K PICALM â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
AP2A1 AP2M1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AP2B1 AP2S1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CD74 HLA-DRA â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
AP2M1 FCHO2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 24189400 26186194
AP2M1 RUN3A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 16189514 16713569
AP2B1 NECP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 16189514
AP2M1 NECP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26186194 28514442 24189400 19380743
AP2M1 EP15R â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 24189400 26186194
AP2S1 AAGAB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 25416956 29892012 31353312 26186194 28514442
AP2M1 AAK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25852190 26186194 28514442 24189400 19380743
AAK1 AP2B1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 33961781 34079125
AMPH AP2A2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ITSN1 AP2B1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 34079125 18654987 22558309
EPS15 AP2B1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 19380743 34079125
EPS15 AP2M1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26186194 28514442 24189400 19380743
AP2M1 DIEXF â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 32296183
EPS15 AP2S1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 19380743
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
UBB RNF11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 14755250 33961781
AP1B1 AP2A1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AAK1 AP2M1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AAGAB AP2S1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CLTB CLTCL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR SH3GL2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR AP2A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31959764 24797263 23956138 25754235 20029029 24189400 7534311
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
EPS15 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17474147 7797522 19109251
CBL ITSN1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
AP2M1 AP2S1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
AP2A1 AP2B1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CBL SHC1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AP2M1 DVL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 31340145
ITSN1 EP15R â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32203420 26344197 22558309
STON2 EP15R â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 18200045 11381094
AP1B1 AMPH â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 9280305
EPS15 AP2A1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8662627 9049247 10764745 19380743 10953014
EGFR AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31959764 24797263 31980649 24067654 23956138 25754235 20029029 24189400
STON2 AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 11454741 26186194 28514442 19380743
AP2M1 NUMB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 28514442 24189400 23211419
PPP2R1A CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
CFTR PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
NTRK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748052 11733534 25921289
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
AMPH MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK1 AMPH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15262992
NUMB AP2A1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17203073 23211419 12942088
AP2A1 EPS15 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
AP2A2 SHC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31980649 16713569 8617812 24189400 19380743 16189514
AP2A2 ARRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
ARRB2 AP2B1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21118812 10097102 17620599 12070169
ARRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
RBP1 AP2M1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26186194 16713569 10910768 28514442 16189514
ARRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
AP2S1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12577067
EGFR BCAR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17145710 17570479 15951569
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
HLA-DQA2 CD74 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
PICALM CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16491119 10436022
STON2 EPS15 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19380743 18200045 11381094
SHC1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
ESR1 WNT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
HLA-DQA1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DQA2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
HLA-DRA HLA-DQA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9312039 1956401 16618111
ITSN1 SH3GL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ITSN1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PCSK9 LDLR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23085658 18250299 22081141 25613181 18753623 17435765
PPP2CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
SHC1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RBP1 REPS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9395447 26344197 31980649 32203420 28514442 23414517
RBP1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11313948 10995764 12242309
AP2B1 ITSN1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
AP2A2 EPS15 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
UBB UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CLTA CLTCL1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
AP1G1 AP2B1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
AP2M1 RALBP1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
EPS15 ITSN1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
SHC1 AP2B1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 19380743 31980649
AP2M1 TGOLN2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
SHC1 AP2M1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 24189400 19380743 31980649
AP2A1 SHC1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 31980649 8617812 11302736 28514442 24189400 19380743 16189514
KIF4A KIF4B â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
EPS15 STON2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RALBP1 REPS1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
AP1G1 AP1B1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 11409905 9733768 23415225 26344197 22939629 7593184 10535737 10747088
SHC1 CBL â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9234717 9541596 15677445 8621719 16713569 8950973 10025673 10570290 8662998 19380743 9461587 9434624
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
AP1B1 AP1G1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AP1B1 AP2M1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
EGFR EGF â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 25453753 30083275 21822280 12620237 19531499 25080504 12093292 22729867 23597562 18427122 26280537 18271526 10970856 15620700 11684674 21439278 8663535 28988771 2790960 10788520 10085134 16274239 25241761 17697999 9135143 12297050
SHC1 EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10595738 24797263 24658140 7542744 21278788 9130710 28065597 10766863 10635327 8034616 24430869 7518560 12577067 19531499 31959764 8810340 9742218 11196191 23799367 23956138 9756944 16713569 11370743 8665853 18271526 15657067 11408594 20473329 22973453 16729043 20935677 20067773 7506413 16273093 25754235 8610109 24189400 26551075 9388490 8887653 31980649 7542991 9544989 9020193 25187647 25402006 30544639 10049786 8662998
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
LDLR PCSK9 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NGF NTRK1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NTRK1 SHC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
AP2A2 AP2B1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
EGF EGFR â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
AP2A2 AMPH â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 8552632 28514442 10748223 9280305 9195986
EPS15 AP2A2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 10809762 18362181 8662627 9049247 26822536 19380743
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12213123 8491186 8950973 9927207 9733714 8112292 10356320 11370743 32062451 8294403 16371368 22057045 9045692 9032244 8995379 7514169 9175774 9541596 8663178 7629070 9019162 7597091 7798267 9544989 9488479 8940013 10570290 15812354 11792427 8621719 24430869 7650032 11453982 16713569 7516467 10477741 8662733 11302736 26551075 9254595 7559490 12441060 8662998 8235613 12485888 28690151 16520382 8939605 11505033 9129019 11707405 15888547 8647288 7524086 25416956 24189400 11827484 12149229 8195171 21725358 9020193 10049786 9797459 9886492 33961781 9126968 8626525 7537740 12577067 11964172 12898421 8810340 22974441 19380743 9434624 10080542 9083103 21706016 15688026 7535773 31980649 8561895 7744881
AP2B1 AP2S1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
AP2A2 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
DVL2 WNT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23821037 15936275 10698942 9716412 17130287 9674432 17627283 11358862 11101902 12015986 14636582
FZD4 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12958364 27096005 23331499
DVL2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12958364
AAK1 AP2M1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877457 11877461
AAK1 NUMB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25904845 18657069
CLTA AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTC AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 CD74 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 HLA-DRA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP2A1 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A1 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A1 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 HLA-DRA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 CD74 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12577067
AP2A2 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A2 CD74 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2A2 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A2 HLA-DRA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA1 AP2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DPA1 AP2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CD74 AP2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA2 AP2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DRA AP2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CLTCL1 AP2B1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
HLA-DPA1 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CLTB AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
HLA-DRA AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CD74 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA2 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CLTCL1 AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
HLA-DQA1 AP2M1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
HLA-DPA1 AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA2 AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CLTCL1 AP2S1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
HLA-DQA1 AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
CD74 AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DRA AP2S1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
PPP2CA ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
BCAR1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
BCAR1 CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
EGF CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CD4 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DPA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD4 HLA-DQA2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 20346773 23580664 11827988 21543337 22426112 16461343 2530588
CD74 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CD74 SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
CLTA HLA-DPA1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DRA CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DPA1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
HLA-DQA1 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
EGF EGFR â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
ESR1 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10894157 15075211 20889718 8770893 19423651
EGF GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17081983 19531499 17673906 10973965
EGF EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 131.0 1.0 Omnipath 17145710 17081983 21822280 20813200 23613900 9135143 25453753 21303971 10209155 26821125 12297050 27387652 25241761 30083275 12093292 30197274 21649524 19531499 18762250 16729043 26921391 17697999 17575160 21722395 12620237 19129184 10788520 23331499 3494473 15620700 14568001 15958209 24096486 18253097 16843263 18320059 21532939 10085134 22260327 15708576 26280537 23912460 21858221 11116185 10970856 27462018 18427122 25080504 20953304 19135477 11684674 8639530 27564112 18270696 2790960 17971399 23185569 19895983 28988771 29617357 23597562 19531623 23950932 21071413 8663535 6289330 16274239 17563729 21439278 20458382 22216880 18271526 12771140 21311755 24709886 25366117 12648462 21107857
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
PPP2CA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EPHA2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12400011
EPS15 SH3GL2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
EPS15 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7797522 17474147 19109251
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
WNT5A FZD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10990458 16602827
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
HLA-DPA1 SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA1 SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DQA2 SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
HLA-DRA SH3GL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 8397411 10480952 9202021 15749704
PCSK9 LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22081141 29209441 17435765 25613181 23085658 18753623 18250299
PPP2CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 10592173 7780739 18588945 2154696 20626350
SHC1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10996427 23584453
NGF NTRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 17145710 8155326 9083066 11729324 27908981 22666365 17404842 24224055 25611061 14985763 9290260 9857023 28090201 12067229 23772401 10490030 11114882 27229480 1706478 11738045 10713102 9547236 1849459 9775403 17409494
NTRK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8155326 9715270 8226808 15056278 10708759 8552402 9856458 23331499 10629055 10092678 12446789 8524391 25921289 7541035 8183561
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129