Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EGFR ABCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12196520
ARHGAP1 RHOC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HNRNPA1 ARHGEF12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ARHGEF12 IGF1R â—¼   COLOCALIZATION 2.0 0.8 intact 11724822 5214835
TP63 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21930790 17935121
DIAPH1 RHOB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15944396 17198702
TEC ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 SEMA4D â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18025083 15210733
GNA11 GNAQ â—¼   GTPASE_REACTION ✅ 2.0 0.8 Reactome 8073283 7937899
KLHL20 CUL3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 20389280 7900485
RHOB CD44 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
IGF1R ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30898150 17307140
RHOB MYO6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
PTPRF RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 25458010
PLXNB1 RAC3 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
GAN CUL3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15983046 31944090 21145461
RHOC RHOA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31871319 31980649
EGFR CD44 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23265944 12093135 16565089 15597342 11606076
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR PTPRF â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24189400 24797263 31980649
ARHGAP1 RHOA â—¼   GTPASE_REACTION ✅ - 0.87 0.87 Signor 32203420
RAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 16331275
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
RHOB ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
RHOA ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
RHOC ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
GNA12 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12515866 11094164 12024019
DIAPH1 ERBB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
ERBB2 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
ARHGEF12 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 11094164
GIPC1 MYO6 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
PLXNB1 RND1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ARHGAP1 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
ARHGEF12 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPS6KA1 VASP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 8182057 14679200 21423205 24097826 20463151 21451103 18637808
ARHGAP1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 32203420 9535855 9548756 9407060 11927263 31467278 16189514 20660160 14749388
SEMA4D ARHGEF12 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
RND1 ARHGEF12 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
ERBB2 ARHGEF12 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12220504 15210733 12196628 12730235
GNA13 ARHGEF12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12515866 11094164 12024019
ARHGEF12 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9789025 17145710 15364580 23405219 32203420 9113980 9641915 20300064 10592173 11373293 12515866 11094164 11149925
RHOA DIAPH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22820501 12773565 18218625 16109481 15864301
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
RPS6KA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10949034 15528270 19925796 15461668 25336146 11139588 12118371 30034315 15059947 16076840 7491495 12093745 11432835 10411321 11507039 9528769 7838153
SEMA4D PLXNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11937491 20877282 27533782 24043639 11245885 12198496 10520995
SEMA4D PLXNB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 27533782 11245885 26633812 15330859