Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SOD1 LSM8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LSM8 LSM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
PARP1 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
HIST1H3B HIST1H3C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
H1-1 CHD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C2 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
H3C2 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19766566 8009287
H3C2 RBBP7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H3C2 RBBP4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
PARP1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
YWHAB ACIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CNTROB APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
BANF1 PWWP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BANF1 DDHD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BANF1 PPP2R1A â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 20711181 22770216
BANF1 PPP2R2A â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 20711181 22770216
BANF1 PPP2CA â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 20711181 22770216
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
BTF3 EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17312387
CANX RNF113A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SOAT1 CANX â—¼   COLOCALIZATION 2.0 0.8 intact 8372609 22045338
SMARCA2 CNTROB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PARP1 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
XPC DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20368362
PARP1 DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PPP2CA DDHD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11328814
EHMT2 FZR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22178396 15774718
LMNA EMD â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 30488537
ESR1 EPHB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17685427 20484412
SP1 EPHB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9918860 10751319
FGFR3 RELA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 PKM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 RALBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNRPD3 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HDAC1 GATA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18250304 0711824105
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
SP1 KRT16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12954631
LMNB2 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LMNB1 LMNA â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SP1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18173747
SP1 MTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11368903 24010737
SOX2 NTRK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22265740
PARP1 PPP2R2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPP2CA RBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15467457 8204372
PPP2CA RBL1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 15467457 8204372
PPP2R2A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1328247 19114990
PPP2CA RBL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18927618 15467457
PPP2CA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24382322
RBBP4 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RELA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
SMARCA2 SMARCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10078207 16713569
STAT3 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132009 18447642
SP1 TMPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19747485
SP1 SRF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10602487 10330138
MDC1 LMNA â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
PPP2CA PPP4C â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CBX1 CBX3 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
DDB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24249678 26679995 25189618 34026424
HNRNPC HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DDB2 HIST1H3C â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
DDB2 HIST1H3B â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
ACIN1 HNRNPC â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
BCL7C ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 18809673
BMI1 LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26468281 34316702
BMI1 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 20668194
BMI1 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CBX1 RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
MDC1 CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 34079125
CD81 SET â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 23463506
DPY30 MTA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 23995757
SOAT1 EMD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 29128334
EPHA7 EPHA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LMNA FLNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22412018 16248985
HDAC6 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32082291 18079183 21532619
VRK1 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28927264 34079125
SOX2 RBBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23667531 21532573
DDB1 HIST1H3C â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
DDB1 HIST1H3B â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
CHAF1B RBBP4 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
CHD4 HIST1H3C â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CHD4 HIST1H3B â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
ACTL6A DPF2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CBX1 EHMT2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CBX1 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
H3C2 CBX1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
EHMT2 CHD4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28486105 26028330 32744500
CBX3 HIST1H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX3 HIST1H3B â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
RELA STAT3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
SMARCC2 SMARCE1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
BANF1 VRK1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
DDB1 LSM2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
SP1 STAT3 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
MTA2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26028330 18451879
ESR1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
ESR1 SET â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 MTA2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18451880 16645043
LMNA RBBP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25948554 19734887
LMNA MDC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30179224 30419336 22412018
LMNA PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 25948554 30419336 22412018
MDC1 SMARCC2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
PPP4C PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 27880917
PARP1 DDB2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
CBX1 HIST1H3C â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HDAC3 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
EHMT2 CBX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24981860 17962312 19706462 15200951 27705803
ESR1 NONO â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33731348 25604459 31527615 20348541
ESR1 FLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21182205
ESR1 RBBP7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23403292 31527615 18577416 21182205
HDAC1 SAP130 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PARP1 HDAC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34079125 16204234 20596014
RBBP4 SP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12091390 16713569 12943729
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
EMD ACTB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17620012 15328537 16189514 12670476
RBBP4 DPY30 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23995757 27705803
SOX2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
EHMT2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 26028330
HDAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16469706 26487511 14722073 31527615 20348541
ESR1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
PARP1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19470756 34079125 16204234 20596014
VRK1 BANF1 â—¼   PHOSPHORYLATION ✅ - 0.86 0.86 Signor 16495336
ACTB ACTL6A â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
BCL7C DPF2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ESR1 ACTB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20308691 19805454 21182205 21182203 31527615 20348541
CBX1 CHD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
EMD LMNB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17620012 34079125 12670476
HDAC3 GATA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11567998 16189514
SOX2 HDAC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 21532573
LMNA NONO â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25948554 22939629 22412018
XPC PARP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125 28760956
BCL7C SMARCE1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
LMNB1 LMNB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
RNF113A SNRPD3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RELA SP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BCL7C SMARCC2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BCL7C SMARCA2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ACTB SMARCC2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HDAC3 RELA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CBX1 HIST1H3B â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
HDAC1 CHD4 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 26949739
FGFR2 FGFR3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 23972473
RBBP7 MTA2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
DDB2 XPC â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BTF3 RPL10 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
DPF2 SMARCA2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CDC37 LMNB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MDC1 FLNA â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HMGA1 SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12665574 20335021
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
LMNA TMPO â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
LMNA LMNB1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
LSM2 SNRPD1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SP1 HSPA1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19336471 18434628 10704399
APTX PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15555565 16713569 15044383
EHMT2 CBX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 17962312 22514736 15200951 27705803 34079125
MTA2 CHD4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21670149 19703393 28977666 12920132 26344197 24981860 9790534 22939629 25247294 20693977 32744500
HDAC2 CHD4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21670149 28977666 26344197 24981860 21258344 9790534 22939629 11003653 9804427 12493763 23752268 32744500 30737378 10545197 26949739 9885572
PARP1 CHD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20693977 26565020
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
MTA2 HDAC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 20714342 19703393 18451879 12920132 26344197 21258344 31980649 24981860 22939629 12493763 11102443 19686092 23752268 11297506 30737378 26949739
LMNB1 LMNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21346760 32814053 25948554 11792809 31467278 34079125 19727227 24623722 30419336 21988832 22412018 26524528 26264872 29568061 16189514 29997244 30021884
RELA MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19530226 20186924
SET PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9353299 21806989
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ACTB CDC37 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ACTB SMARCE1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
PPP2R2A PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711181 8288198
BANF1 LMNA â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BANF1 EMD â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CHAF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
H3C2 CHAF1B â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7219095 19498464
H3C2 CHAF1B â—¼   PROXIMITY ✅ 0.92 0.92 mint 25281560
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
PPP2R1A PPP4C â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
CHD4 MTA2 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
BCCIP SSB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CHD4 HDAC2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
MTA2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6613464 18451879
CHD4 RBBP7 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 RBBP4 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
CHD4 HDAC1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ATP6V1A ATP6V1B1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
PPP2R2A PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17245430 5219546
CBX3 EHMT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
HDAC1 MTA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
HDAC1 RBL1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 9724731 10490602 16189514
ACTL6A SMARCA2 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
MTA2 RBBP4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
RBBP4 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 34518534 11302704 11102443 27705803 17827154 10734134 10220385 9885572 10471499 26344197 21258344 12091390 9150133 16713569 11602581 12920132 20127688 9790534 17643391 11470869 19686092 12943729 9150135 28514442 16189514 27068747 10444591 19703393 11171972 15451426 23752268 20585571 9520398 11118440 31435636
RBBP7 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17255935 22939629 26496610 11102443 27705803 9885572 10471499 26344197 21258344 12920132 9790534 19686092 9150135 28514442 25885317 10444591 19703393 15451426 26186194 23752268
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
SMARCA2 SMARCC2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DPF2 SMARCC2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ACTL6A SMARCE1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
EMD LMNA â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
DPF2 SMARCE1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
SMARCA2 SMARCE1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HDAC2 MTA2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
ACTL6A SMARCC2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
LSM8 SNRPD3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
LSM2 SNRPD3 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
MTA2 RBBP7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCC2 SMARCE1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1A PPP2R2A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SNRPD1 SNRPD3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
LSM2 LSM8 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
VRK2 BANF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20511217 16495336 16371512
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
VRK3 BANF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 25899223 24265311 24945635 28927264 24600006 16371512 33744941 16495336
PARP1 H1-1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18250087 18851700 18927583
HDAC3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19442252 16865259
EHMT2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19690169 17194708 22387026
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
CBX1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15136563 11882902 16622419 20871592 11242053 19111658 15960974 16415788 26527279
VRK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15108802 12082625 17938195 15249581
SRF ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18804439 15837932 1762920 9571041
PARP1 APTX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15555565 19643912 15044383 16713569
PSIP1 BANF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9860958 9038339 3032450 16175173 9188609 16291214
BANF1 VRK1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 Reactome 16495336 16704422 12493765 11285238 10908652 15546916 22770216 17170708 7937898 16371512 9465049 11792822 16339967 15681850
PPP4C BANF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24265311 16495336
VRK1 BANF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 25899223 28927264 16495336 16371512
BANF1 EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25910212 22399800 11792822 25502805 17620012 31515488 32814053 32296183 12163176 11792821 16189514
HDAC3 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
DDB1 DDB2 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB1 DDB2 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19440234 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
DDB2 DDB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 54.0 1.0 Omnipath 9418871 17145710 16751180 27203177 22118460 17041588 20368362 18593899 16964240 12050362 19295130 22039351 11564863 16473935 16678110 17392787 24249678 19109893 12151405 26186194 12812979 16949367 18936169 22822215 14751237 10777491 26410533 16260596 19966799 17360488 12732143
DDB2 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15882621 22039351 19740755 29604309 23319653
EMD VRK1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 Reactome 16495336 16704422 12493765 11285238 10908652 15546916 22770216 17170708 7937898 16371512 9465049 11792822 16339967 15681850
PPP2CA EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
FGFR3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 19901323 10918587 9305919 8272872 12626508 16497976 15592455 17389395 12576423 11350938 11294897 12244095 9083098 8626374 9566874 11940572 11429593 14551213 11850821 17016520 9582023
FLT3 STAT3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10477595 14670306 15253381 16418395 25215878 8920882 9268501
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15653507 25241761
PPP4C HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15805470
HDAC3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11533489 16189514 12419806
PSIP1 HMGA1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 9860958 9038339 3032450 16175173 9188609 16291214
LMNA VRK1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 Reactome 16495336 16704422 12493765 11285238 10908652 15546916 22770216 17170708 7937898 16371512 9465049 11792822 16339967 15681850
SP1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11910354 12473536 9223667 15067326 21831840 17283128
SP1 PAEP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11369448 24060634
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
PKM STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23791887 29127353 22901803 22306293 24115444 28978186 27080861 26542452
SP1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19750005 19420015 12076969 21420382
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11591705 12842894 17188031
PPP4C RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15073167 9837938 16189514
SP1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7636984 8450395 9151857 20538607 11964305
STAT3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19345327 12057007 23335796 16713569 18448488
RELA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12055073 7933095 10671503 20861353
SP1 SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8921911 18586551 18608091 21056687 24946209 11724400 9867871
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
XPC HIST1H1A â—¼   KO_DOWN_REGULATES ✅ - -3.58 3.57 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368