Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NR1H3 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17026988 11035776
CEBPG APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8175747 15109267
CD55 C4B_2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
C4B_2 CD46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12055245 2481448
CFI C4B_2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
CFD ENSG00000244255 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFB ENSG00000244255 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFP ENSG00000244255 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CEBPG AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9621116 7951412
HNF4A AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21298017 20684663
PPARA AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15067378 20613959
CFB C3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 809512 279011
C3 CD55 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFD C3 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 809512 279011
C3 CPB2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
C3 CPN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
C3 CPN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
CFI C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 293746 702059
CD55 C4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6238120 8786315
C4A CD46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12055245 2481448
C5 CPN2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
C5 CPN1 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
C5 CPB2 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 11939578 4098172
CFI CD46 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6214588 1386357
CEBPB CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12773552
CEBPG ITGAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9250811 9360988
CFD CFB â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 809512 279011
CFB CFH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1067618 301546
CFB CFD â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CFI CR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 6214588 1386357
CREB1 IL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
HNF4A GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18513187 9601103
HNF4A TF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8550563 9053305
NR3C1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9510064 2159467
NCOA1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16186500 14551261
PPARA NR1H2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
NR1H2 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15722453
C3 ENSG00000244255 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
C3 CFD â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
DDX31 IGHM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD81 APOA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32900848 30024968
DDX31 APOA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DDX31 DMBT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
C3 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
CR2 CR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 7690834 1708808
NR1H4 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25675114 17333335
HNF4A NCOA1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
C3 CFHR4 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
C3 ITGAM â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
C3 CR2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CFHR1 C3 â—¼   PHYSICAL_INTERACTION ✅ + 0.83 0.83 Signor 27814381
CR2 CD19 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 1702139 9804823 1383329
CD81 CD19 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7636191 9804823 1383329
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
C3 EFEMP2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
CEBPB CEBPD â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 1840554 20102225
CFH CFI â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CEBPB CEBPG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20102225 12177065
ITGB2 KRT31 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
ITGB2 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CFB CFP â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
C3 KRT31 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
NCOA1 ESR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11500849 10809226 11014206 19126643 15604093 10731636 11376110 14715875 12554772
AGR2 KRT31 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
MAPK6 APOA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
C4B_2 CR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10531307 11694537 293688
AGT CTSG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6807977 9570564 20889553
CTSG AGT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11747312 10899625
C3 IFITM1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17337780 15778510 14719373
CEBPD C3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8385337 14725791
ESR1 C3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10418989 8961270 17478088
C3 CFI â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6607952 21788512 2971659
CTSG C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24315997 1861080
C4A CR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10531307 11694537 293688
CEBPG CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10880233 18684932 17335903
CFH CFI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26806831 9291131 1401896
CFI CR1 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 6607952 21788512 2971659
ESR2 DMBT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9259327 10409727 23874500 11014206 15604093 12554772 16282588 9427757 11113179 18451880 9121466 10598586 16713569 11165056 14715875 11376110 9774463 10760302 20608937 9192892 11003650 26487511 11867769 10454579 12574227 17363140 9773983 10731636 11358671 11250900 11682626 23975195 17627277 16606617 12630920 12714702 9192902 12738788 16957778 15140878
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
TFAP2A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10497269 19458056 9850080
ESR1 GJA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15028626 12810571 22962310
ESR1 TF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12459033
ESR2 TGM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
NR3C1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17978169 24399729
NR3C1 IL1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27371733 27076634 10465310
NR3C1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18174358 24500711 27371733
NR1H4 NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14698205 11136553 18391212 20338915 14684751
NR1H2 NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12470667 11875109 22194611
PPARA NR1H3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18758514 12595494 18498712
TFAP2A NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9015328 7794935
CFH CRP â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EFEMP2 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
C3 VSIG4 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
C3 CFP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CFH CFHR1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NCOA1 NR1H3 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
C3 CR1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
C3 CFHR1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
C3 CD46 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
C3 CFI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
C3 CFB â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ITGAX ITGB2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ESR2 NCOA1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 PPARA â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR1H4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR3C1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
C3 CFH â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
PPARA APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16530456 7983038 16492688 20371549 9694537 9748239 12882972
HNF4A APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7838720 9003181 7961760 8464705 22282358 8626539 9357782 7615825
ESR1 APOA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11013347 18005483 9535920 17532863 23293065
HNF4A APOA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8626539 8464705
NR3C1 AGT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20978123 15630592 17475670 15854165
CEBPB C3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25617152 22171262 21308746 18247123 10594926
CFI C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16023208 1401896 26806831 9291131 8648130 2141838
CFH C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16023208 19050261 11367533 21979047 21317894 9988761 16612335
C3 ITGAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 4062888 16857732 7512600 7679388 12554829
C3 CR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10382758 2551147 9988761 2141838
C3 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10608878 1060887810608870
C3 ITGB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 4062888 26293614
C3 ITGAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 4062888 11073102 26293614
C3 C3AR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8702752 11342658 8765043 20527893 9476119
CR2 CD19 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9597125 14688345 31732528 1702139
CD40LG IL2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11581322 15034038 17200410 17371980 23125331 8760829
CEBPD CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7646815 18703634 7910803 11559710 18092000 1741402
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB CRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17513780 17335903 11035101 12393563 11160296 14522018 12667216 18684932 22750226 23955082 16116232 10880233 23361365
CEBPB IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21917825 12072435 9372929 16867259 20702408 17283046 10464291 16569740 10801783 15812237 22260630 10841183 10838190 10383163 9376596 17386941 10956548 12759449 11278846 12468538 11035101 11801594 2112087 12355443 15383601 16439360 19806478 22074460 16399630
NR3C1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25202013 9817600 9428795 11279134
NR3C1 CEBPD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10649448 1840554
CEBPG IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9916895 10841183 18247123 19806478 11474579 8999951 18438857
CFH CRP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20042240 17293598 17399790 19680263 21930971 28533443 17339482 10490997 18786923 29374201 26961257 19850925 19084272
CFHR1 CFH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8663389 16189514 27814381 19528535
CREB1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11313407 12370343 17548609 12626549 15993752 12432566 8670878 8814256 11238674
NR3C1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20203101 16713569 8449898 7621901
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
HNF4A PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11981036 15912134 19933841 17022998
NCOA1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11698662 10731636 9626662 12163133 21775429 15888456 9407140
NCOA1 NR1H3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20682316 25962847 15604093
NR1H3 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 24713062 21071413 16189514 14960721 8621574