Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CDK6 CCND3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CCND3 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16609025
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
CDK4 CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SKP2 SKP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CCND1 CDK1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
CDN1B CUL1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18805092 10559916 34237211 11961546 22959436
CDK1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 14681455 8565853 16009130 1628647 7799941
1433E CDN1B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16189514 12042314 15057270
1433E TSC2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 17979178 12438239 19608861
SPDYA CDK2 â—¼   RELOCALIZATION ✅ + 0.81 0.81 Signor 33015044
SKP2 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6540196 18239684
CUL1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21145461 9663463
CUL4A SKP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22474075 21145461
CSN5 CDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23926101 21145461
CKS2 CDN1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDK7 CDN1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GRB2 1433E â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
CKS1 CCNE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CKS1 CCNE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SKP2 AKT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19270694 23911321 19270695 21358672
AKT1 UCHL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25640309 16027165
CKS2 CCNE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDK2 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
CDK2 UCHL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21319273 23543736
CCNA2 CCNA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TSC2 CDN1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17470459 15355997
CDK5 CCND1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 23455922 33961781 21654808
CDK5 CCNE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 23455922 23602568 33961781
CCNE1 CDK7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDK1 CDK3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CCND3 CDK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CCND1 CUL1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AKT1 SKP2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CUL4A CDN1B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16537899 16467204 26613412 19056892
CDN1B RHOA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23333463 19470470
CKS2 CKS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 2227411
CCNB1 CDK7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 26186194 11113184
CCNE1 CDK4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9716181 28205554 28628118
CCNE1 CDK6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9716181 28205554 28628118
SPDYA CDK2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17671428 12839962 12972555 19622356 16951407 11980914
CCNA1 SKP2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
SKP1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 9858587 33422522 26496610 16209941
TSC2 CCND1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26977878 16357142
CCNA1 CDK1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CDK1 SKP2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CUL4A CUL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17079684 32235678 21145461
CUL1 CDK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23455922 21145461 26186194 9636170 28514442
CDN1B CCNB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 8756624 31822694 26496610
CDK5 CCNA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 23455922 33961781
CCND1 XPO1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21654808 12529437
CCNE2 CDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 9840943
CDK5 CDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 33961781 28514442
CDK3 SKP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 23602568 26186194
CCND2 CDK5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK2 SKP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CUL1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16209941 33422522 26496610 21145461
CSN5 SKP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31950832 21145461
CDN1B UCHL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12082530 16189514
CDN1B CDK3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 9811456 26186194 28514442 23602568
CDN1B 1433T â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18281517 12042314 18593906 16713569 17470459
1433E XPO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23472066 22863883
CKS1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 33422522 18471975 26496610 11907280 16209941 19483727 26186194 28514442
CDK5 CCNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 25852190 26186194 28514442 23602568 32707033
CCNB1 CDK3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27030811 28514442
CDK4 CDK6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 28205554 28628118
CDK5 CCND3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 23455922 32296183 26186194 28514442 23602568
CSN5 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12732143 26976604 33961781 16964240 21145461 19615732 32047038 27029275 25349427 18606781 23357576 17079684 26186194 22956996 28514442 19295130 18850735 22474075
CDN1B CSN5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15688030 12082530 17951406 15480426 18285702 28919423 16951171 19139918 24671224 18202760 22350412
CSN5 UCHL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12082530 16189514 16713569
CSN5 SKP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 34237211 21145461
CDK1 CDN1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 31822694 26186194 24358021 18615582 28514442 23602568 32707033 23543736
CDN1B SKP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16209941 23910095 10559916
CDN1B CDK6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 8822197 25241761 16782892 11360184 18615582 21439954 10022865
CCNE2 CDN1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 9840927 9840943 17254966 24358021 9858585
CCNE1 CDN1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 8978686 20837141 9218599 9891079 31822694 9716181 23910095 9192873 9632134 11940657 14691455 8756624 9660939 17254967 24632684 19470470 17293600 8891332 10393546 17254966 9311993 25241761 12529437 27175940
1433T 1433E â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 31980649 20936779 21988832 17085597 28514442 17979178 20618440
CKS1 CCNB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 30674583 18471975 26496610 28514442 19786724
AKT1 TSC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12167664 15342917 12438239 12150915
CDK1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 33961781 33422522 17679094 25852190 26496610 24302728 19483727 12853968 26186194 21308745 8463339 28514442 9053846 23602568 32707033
SKP2 CCNE1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11237742 22959436 10790373
CKS2 CDK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 25852190 18471975 26496610 26186194 32707033 28514442 23602568 19786724
CDK7 CDK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23455922 25852190 16191191 10393546 15282296 23064645 11113184 8647086 8692842 7629134 16327805 15530371
CDK3 CKS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CCND1 CDK2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CSN5 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34237211 21903097 26265931 29103612 21249194 27774986 25144743 19615732 22767593 24973710 22959436 22956996 18850735 31950832 19141280 21145461 22013077 29863914 22474075 16036220
CCNA1 CDN1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16774918 15583032 33961781 18692475 32814053 10022926 26264872 16189514 7478582 29997244
AKT1 CDN1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16780593 12042314 28919423 25241761 12244301
CDN1B CDK5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15890360 23455922 25852190 26186194 28514442 23602568 32707033 23543736
XPO1 CDN1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19139918 27175940 11889117 12529437
CKS1 CDN1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18805092 23910095 33961781 12140288 16209941 12813041 19584057 28514442
CDN1B GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11278754 16189514 19523899
SPDYA CDN1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12972555 17671428 32296183
SKP2 CDN1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21237244 20160477 12140288 11463388 15075339 23911321 22310285 21503567 19112177 33854235 16774918 23910095 24085301 10559916 15735731 15355997 29137415 12529174 16209941 22959436 12813041 15469821 32265224 18239684 16189514 11565034 26450989 18805092 20663873 12042314 27565346 19686743 20160482 22524983 22632967
CDN1B CCNA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18177895 26496610 27720894 31822694 9716181 12947099 8684460 20596027 16209941 28514442 9660939 12501191 15890360 33422522 24632684 17254966 9311993 26186194 9724724
TSC2 1433T â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15161933 17353931 12438239 16713569 28514442 20618440
SKP2 CKS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12140288 15980415 11463388 19786724 11231585 23589337 12529174 16979657 16209941 12813041 28514442 18239684 16189514 33422522 15772084 16338391 17409098 18519678
CKS1 CDK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26344197 25852190 18471975 22939629 9774639 26496610 26186194 32707033 25416956 23602568 19786724
SKP2 CCNA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20160477 33989513 9858587 33422522 24632684 15355997 7553852 26496610 16209941 27720894 31181401 26186194 10559858 28514442 18604603
SKP2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9858587 15355997 33989513
CCNA2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9858587 15355997 33989513
CDK6 CCND2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16189514 9178893 30217970 11360184 28205554 16713569 28628118 23602568 11358847 10022865
SKP2 CDK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20160477 23455922 26496610 22770219 23602568 7553852 9636170 9858587 15355997 25852190 10386600 16979657 28514442 16189514 18604603 33422522 19686743 19270695 26186194 10559858
CCNA2 SKP2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CCNA2 CKS2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CCND2 CDK2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CCND3 CDK2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CDK2 SKP2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CDK2 CKS2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CKS2 CCNB1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 30674583 18471975 26496610 28514442 19786724
CCNE1 CDK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CDK2 CDK7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CDN1B STMN1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 15652749 21423803
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CCND2 CDK6 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
CDK2 CDK3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 28514442 23455922 26186194 33961781
CCND2 CDK4 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
CKS1 CUL1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 28514442 19786724 21145461
CCND3 CDK6 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CCND2 CDN1B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 25910212 26186194 28514442 9325318 16189514 10022865
CDK2 CCNE1 â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 19561641
CCNE2 CDK2 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
CDN1B CCND3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 8978686 10342870 9716181 16782892 23718855 11360184 26186194 10597239 28514442 16189514
CDK6 CCND3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 16782892 11360184 21516116 8114739 26264872 23602568 14681455 32814053 9716181 16713569 32707033 33854235 27107012 32296183 17517622 15232106 30217970 28514442 25416956 16189514 26186194 29997244
CDN1B CCND1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12036906 8978686 33961781 26496610 17053782 11360184 33854239 7478582 21654808 16431923 9106657 19767775 11940657 10908655 28514442 25416956 17254966 9311993 19556892 15695403
CDK2 CDN1B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 8978686 23455922 17671428 16782892 26496610 17053782 9218599 12417722 33854239 23602568 21423803 31822694 17698606 12972555 10585280 11521189 9472014 9380407 8684460 15355997 25852190 9192873 9632134 11940657 15619620 18850315 16326706 19631451 10198259 16189514 9660939 26450989 28514442 15890360 17254967 17418410 9658399 10323868 24632684 33422522 18285702 10393546 17254966 9311993 25241761 12800980 19139918 27998760 26186194 24358021 12529437 27175940 18615582 9724724 21439954 15557281 15647383
CDN1B CDK4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 8978686 23455922 16782892 17053782 20837141 11360184 33854239 23602568 8822197 9106657 32707033 23543736 9632134 11940657 18850315 10198259 10908655 16326706 16189514 28514442 10022865 9464540 9658399 23707388 19470470 18285702 25241761 9311993 26186194 18615582 21439954 15695403
SKP1 CKS1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 15772084 16979657 16209941 12813041 23589337 27705803 19786724
CDK6 CCND1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 21654808 17420273 33961781 11739795 17517622 11160398 24855949 15232106 9178893 24953629 33854235 11360184 16713569 19075005 10580009 10022865
CKS2 CDK2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 23455922 25852190 26496610 26186194 28514442 19786724
SKP2 SKP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 20160477 16880511 19398581 18667692 17463251 34237211 27705803 23911321 22310285 15070733 19270694 27220724 26087183 9827542 22464731 31467278 18818696 24085301 10559916 30254149 29137415 23770852 30728155 10531035 12813041 15469821 20041211 18239684 16189514 28614300 29499133 12609982 9430629 33422522 34080260 16376880 11961546 32350066 23868976 11099048 22524983 10918611 10559858 15342634 23261596 15456869 26474281 22632967 16275325 29997244 15452136
CDK2 SPDYA â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
CDK4 CCND3 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 8153045 21516116
CDK3 CKS1 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 32296183 26186194 28514442 7809159 23602568
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CCNB1 CKS2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
CDK2 CKS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 8601310 23455922 33961781 12140288 26496610 7809159 23602568 19786724 26344197 31467278 25852190 16979657 28514442 16189514 15772084 9840943 26186194 17409098 29997244
CDK2 CCNE1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 8978686 23455922 15980415 24771265 15670215 15514162 26496610 20837141 25728284 9891079 33854239 10330164 8867812 23602568 14681455 11433299 16431923 9716181 20587660 28137908 14701826 14536078 17361108 33854235 10827081 8662825 9472014 25852190 16223725 9192873 11940657 12839982 11132966 10359664 7799941 21092281 8647086 8756624 19631451 28514442 21372285 9660939 17431037 17254967 29439025 19470470 21241890 9840943 17970072 1388288 18559665 12800980 15004009 26186194 24358021 23853094 12529437 15557281
CCND3 CDK4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDK1 CKS2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNE1 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCND3 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CCND3 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17517622 8114739 26186194 27107012 23602568 10477583 16782892 21516116 25416956 29997244 31515488 32814053 15232106 32296183 11360184 16713569 9716181
CCND3 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 11896535 25416956 16985050 34591612 21988832 14597415 17517622 16782892 10342870 21516116 23880157 15232106 16189514 11360184 26496610 25910212 26186194 27107012 10477583 19237555 32296183 14641107 9106657 9508775 31515488 9716181
CCNE2 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
CCNE1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
CUL1 CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
CUL1 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
CDK7 CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7533895 19847258 17386261 17884153 19667075 15703371 11959850 12648680 11900249 16697054 19809470
AKT1 TSC2 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 10722653 10949026 11715018 11756412 11923280 15169778 15808505 16697215 17052453 17680028 18372248 18570873 18636226 20138985 20214616 20398329 20832730 9812896
AKT1 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23807222 28446188 22733130 19270695 20160512 19549334 21963805
AKT1 TSC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 75.0 1.0 Omnipath 16873412 12820960 17018601 11756412 32308763 11923280 16697215 19690332 21893193 20398329 18372248 21177249 12438239 18466115 15808505 29042482 20138985 15342917 17597835 20214616 12271141 16702951 20837138 17570479 26844273 15169778 17386266 10949026 16288292 24590173 11715018 15661536 18636226 18411301 20028854 9812896 16636147 20169078 17680028 12172553 19664994 18707149 10722653 12150915 18570873 20832730 12364343 17052453 18283331 21666717 27451907
AKT1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18354084 29665367
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CCND1 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7533895 19847258 12814430 17386261 16782892 17884153 19667075 15703371 12648680 11900249 12459251 16697054 19809470
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
CCND2 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CCND2 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10477583 17517622 16713569
CCND2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 17517622 27107012 11896535 10477583 9325318 31515488 16189514 32296183
CCNE1 SKP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
SKP1 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
SKP2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 11237742 12648680 11900249 16697054 18931676 19809470 15459660
CDK2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 17145710 16223725 21092281 15004009 10962581 9840943 8643455 24358021 8861947 21372285 17570479 11237742 10330164 22558078 10652300 19561641 10477583 18691976 23853094 12144826 10500095 1388288 10827081 17970072 28137908 19470470 8756624 10809788 14536078 15364936
CCNE2 SKP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
CCNE2 SKP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
SKP2 CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
SKP1 CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
CDK7 CDK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
CDK7 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 85.0 1.0 Omnipath 16565220 18767875 11113184 33657372 27303922 19690332 19667075 15703371 10913154 14988404 1532335 29793495 20360007 7799941 19158392 19664995 33574676 19809470 8548828 7533895 17386261 34489572 26881937 17554681 20068231 18452278 21900495 18669648 12814430 16327805 18691976 15868411 8441405 21778139 25849598 27908669 12459251 1833185 19651622 22263797 19847258 19707596 17924679 20347419 29435156 18220336 34370741 19369195 22505032 21468563 17884153 12663041 22425727 7944411 12648680 11900249 8344251 16697054 31429764 24970150
CDK1 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 83.0 1.0 Omnipath 17081983 18767875 9731215 20230923 19690332 17693683 11135364 19413330 18187866 19664995 19415658 18578522 16083285 20068231 18452278 94064639 1737801 18491316 18669648 8245003 16427064 93315482 17287340 16094384 19651622 20058876 8376365 8325880 17924679 18220336 19664994 18707149 8125092 8325881 16964243 33839152 18212344
CDK7 CDK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
SPDYA CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11980914 33015044 19622356 16951407 12839962
SKP1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7553852 23602568 16979657 9636170 26496610 25852190
CDK7 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 18767875 11113184 25271736 7880532 19690332 19667075 15703371 14597612 20360007 21565702 19809470 15302935 8443411 7533895 10085115 15671017 17095507 10886368 17386261 20068231 18452278 9244189 8069918 11840777 1396589 17570665 16325401 16327805 25788262 11959850 15530371 11532001 19056339 9130709 14551212 17192257 19847258 22505032 17884153 20147522 12648680 11900249 16697054 93010995 8393783
CDK2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 7553852 20160477 23602568 25271736 18239684 28446188 23226679 10386600 19270695 26496610 16189514 25852190 26186194 25788262 9858587 22770219 15355997 10559858 23807222 22311674 16979657 9636170 19686743 19270694 18604603 23455922
CDK4 CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7533895 14597415 19847258 8139570 12814430 17386261 16327805 16782892 28368408 17884153 19667075 15703371 14754892 12648680 11900249 12459251 16697054 19809470
CDK5 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16925597 26944284 26708747 20630875
CDK7 CDK6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
SKP1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SKP1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258