Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CCP110 CETN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16760425
PARP1 CETN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
DYNC1I1 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNC1LI2 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNLL2 DYNC1I1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DYNC1I1 DYNLL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNC1LI2 DYNC1I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNLL1 DYNC1I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNLL2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNC1LI2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNC1LI2 DYNLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
DYNC1LI2 DYNLL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18535146 10491388
HSP90AA1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
HSP90AB1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
VIM GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSPA8 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
LAMP2 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9038169 9151685
HSP90AB1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
HSP90AA1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
PARK7 KIF1B â—¼   CLEAVAGE ✅ 2.0 0.8 intact 23831022 8433088
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CETN1 SGSM1 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CETN2 POC5 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CETN1 H2AX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
H2AX CETN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
H2AX PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 MYCB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZFAN5 CETN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 CCHCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 MCM3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 SH3B4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 ZN295 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CALM CETN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16760425 18694559
CETN1 TWST1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
XPC SP16H â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 SP16H â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 TYDP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 DYXC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 BCKD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 DYH14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 FBX16 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 DEFM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF1B DEFM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 VIP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 RABP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 EFC11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 K1407 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 LDB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 TTF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 CUL7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 LHX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 SGSM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 SPRY3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 CETN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 KIF1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 KIF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 XPC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 PKN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 CTU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CETN1 CETN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
XPC PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CCP110 CEP290 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
PCM1 CCHCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27107012 32296183 34079125
DYH14 CETN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CETN2 SGSM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 32296183
XPC CETN3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 30251372
CETN3 SGSM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 32296183
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
KIF1B KIF1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32814053 28514442 33961781
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MCM3AP PCID2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PARP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 34079125 26831064 25252691
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
BCKD CETN3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 32707033
BCKD CETN2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 32707033
CETN1 POC5 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
H2AX CALM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20000738 16522924
PARP2 VIM â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
XPC H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 28242625 19805520
XPC PARP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125 28760956
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRCA1 TUBG1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CETN2 SFI1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CETN3 POC5 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PARP2 PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12217960 11948190 19629035
DYNC1I1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
DYNC1H1 DYNC1I1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DYNC1I1 DYNLL1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
DYNLL1 DYNLL2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
H2AX PARP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28796254 28242625 16377563 27728808 18406329 28514442 20000738 20085707 16522924
PCNT CALM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10823944 33961781 12221128 18694559
CEP290 CCP110 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 22441691 8392017
FBXW8 CUL7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21572988 12481031 18498745 23029530 31343991 23045529 17998335 17332328 16142236 10531037 21946088 17205132
CUL7 FBXW8 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
LHX4 LDB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 35140242 32296183 24981860 26186194 28514442
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
LDB1 LHX4 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
HSF1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
H2AX BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18344987 12419185 26095369 20681793 19805520 18001825 31501894 26121674 10959836 12485996 18001824 19766185 11927591 34321665 29499138
UBE2N H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17709392 18077395
HSPA8 ARL13B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 CETN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
SFI1 CETN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16956364 16189514 14504268
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
DYNC1I2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
PCNT HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
PLIN3 HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
RNASE1 HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
VIM HSPA8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 IFT88 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 PLIN2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
PCNT PCM1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 26638075 24816561 11171385 34079125
PCM1 PCNT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12403812 24816561 11171385
H2AX SP16H â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 24981860 28242625 28514442 18406329 16522924
DYNC1I2 DYNLL1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
DYNC1H1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CETN3 MCM3AP â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CETN2 XPC â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
DYNC1I2 DYNC1LI2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DYNC1H1 DYNC1LI2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DYNC1H1 DYNC1I2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
PRKN CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20418918 12628165 15194120
BRCA1 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18001824 18001825 17145710 12419185
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 PARP2 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 PARP2 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 XPC â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
CCP110 CALM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 26638075 16760425 18694559 17719545 27173435
XPC CETN2 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
XPC CETN2 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11900249 12648680 15703371 16697054 17884153 18199748 19809470 19847258 20211143 20457011 22615860
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
HSF1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9880553 21932106 10440232 19818013 20045681 20668218 15706094 17965413
HSF1 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21932106 24384723 15221402 20185824 20817212
PARP1 PARP2 â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 18835851 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21037379 21060331 21076181 21270334 21337561 21376743 21818122 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368