Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PPARG CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15741503 17237441
IRF3 JUN â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
IRF3 CXCL14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11991981 9891032
IRF3 CXCL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12354379
IRF3 CCL5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11991981
CCL11 DPP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
DPP4 CCL11 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
CCR2 CCL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12554737 9276730
CCR3 CCL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12554737 9276730
CCL21 CCR7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8383238 7851893
IRF2 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11413310 15860458
STAT3 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17510282 20038813
DPP4 CCL5 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
STAT1 CCR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16628196
CXCL11 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22633458 15178708
PPARG CX3CR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19850645 16908772
CXCL10 DPP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
CXCL10 DPP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
JUN CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19299558 23250032
CXCL10 DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
DPP4 CXCL11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6491341 18275857
IRF2 CXCL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19299558 17202361
CXCL11 DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
STAT3 CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25453873 28072604
CXCL12 DPP4 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
CXCR4 CXCL14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23669361 8427967
CXCL14 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32239134 28360196
RELA CXCL9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12403783 19157479
DPP4 CXCL9 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 21314817 8090457
PPARG CXCR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18292390
STAT3 CXCR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20185584 23024284
PF4V1 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22633458 28859966
NFKB1 CXCR5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21677778 21469117
STAT1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19129475
PPARG IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19160541 15187132
KLF4 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22653776 17719562
IRF1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12817009 28166218
IL10 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12773629
IL10 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12773629
IL1B IRAK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12538665 17507369
STAT3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17386941 31886314
IRF2 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9625761 18802049
STAT1 IRF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15778351
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
STAT3 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17129668
STAT1 LY96 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21572044
STAT3 MYD88 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7567467 12244150
TNF PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22078880 20651683
RELA REL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211837 10498867
RELA STAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
RELA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
DPP4 CCL5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 21314817 11390394 9516414
MYD88 IRF5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15665823
DPP4 CCL11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21314817 18275857 11390394
DPP4 CXCL9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21314817 18275857 11390394
CCR5 STAT3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14674010 11350939
RELA STAT3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HDAC3 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
STAT3 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730629 8662591
CCR4 CCL5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12270118 8573157
CCL5 CCR3 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
IRF5 IRF3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11303025 16189514 12138184
CCR1 CCL5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9336350 9115216 9289016 12270118 11449371 10910894 7545673 7622448 11116158 8530354 14637022
CCR3 CCL5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8642344 9289016 11449371 7622448 10733106
CXCL9 CXCR3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12782716 9625760 11259614 9660793
HDAC3 RELA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IRF1 STAT1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
IRF7 IRF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11162841 18641315
STAT1 IRF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16512786 10764778
JUN STAT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
STAT1 STAT3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
JUN DDIT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23661758 10523647
REL RELA â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
IRF3 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20483755 15367631 15664995
CCR3 CCL11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8642344 8676064 8609214 25450766 9712872 10733106 23597562 9207005 9169459
CCL13 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10699158 23846739
CCR10 CCL28 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10781587 10725696 10725697
CCR5 CCL5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9289016 11449371 10488147 8663314 11116158 10477718 9334377 9207005 14637022
PPARG CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909507 20663893 11932328
IRF5 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18332133 20483755 12138184
CCR5 CXCR4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12429730 18632580 15660419
RELA CCR5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19469019 9840284 12745546
NFKB1 CCR7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19164127 11830455 22158872
JUN CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21465475 17550983 21312239
RELA CXCL14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16825293 8530498 19929594
CXCR1 CXCL6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1840701 3260265 9164944
NFKB1 CXCL9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12403783 17274000 19157479
JUN DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19299913 22622069 12069855
HDAC3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12150997 15811852 15494311
STAT3 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20568122 19129475
NFKB1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19752329 8016102
IFNG STAT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12040185 7796299 8156998
IFNG STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10707961 11960596 28264935
JUN IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15699140 25567680 28100679
IRF5 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22025054 24453413 21240265
IL1B MYD88 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17507369 17890055 9430229
IRF5 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26315890 21240265 25565375
STAT1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17386941 23922745
IRF7 IRAK4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15361868 15767370 15492225
RELA IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12077266 18694960 21200019
TIRAP MYD88 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17583698 20048342 24316379 33961781 11544529 28483816 21334391 16189514 17258210 18221795
STAT1 MYD88 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18024894 7567467
NCOR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22395773 20462215
NFKB1 STAT3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25241761 12057007 16713569
PPARG TNF â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 10432118 17681149 23390297
STAT1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16481475
XCR1 XCL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7875320 8849694 7602097
NFKB1 REL â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
MYD88 IRF7 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 16484229 15361868
IRAK2 IRAK4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CCL5 CCR5 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CCL11 CCR3 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
IRAK2 MYD88 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NCOR1 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
IRAK4 MYD88 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
IRAK4 CD14 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK2 CD14 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
LY96 CD14 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 CD14 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IRF7 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14517278 15210742 14703513 9566918 17823124 17157040
CD14 IRF3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14517278 15210742 14703513 9566918 17823124 17157040
CD14 IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 TIRAP â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IRAK4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19592493 20485341 11960013 18829464 12297423 19498957
CD14 LY96 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 22078883 16467847 22158869 18233961 18297073 14517279
LY96 CD14 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 CD14 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 CD14 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 TIRAP â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CD14 CXCL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRF3 LY96 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14517278 15210742 14703513 9566918 17823124 17157040
IRF3 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16253303 19541850 23405030 20483755 18691624 16490936 12821121 24257594
NFKB1 CCL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16604092 11076795 15972682 10586089 14660485
RELA CCL11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 22254182 18714023 15531761 16604092 11076795 15972682 10586089 14660485 16428072
CCL11 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 15207250 9276730 9115216 9195948 11264152 22633458 12554737 12149192
CCL11 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9660793 96607939660793 22633458
CCL11 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10477718 9468473 10699158 9790730 11264152 22633458 12964882
CCL11 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 10488147 10699158 22633458 12218106 23597562 25450766 12149192 16102831 8642344 9169459 9005985 16339911 8676064 9276730 9207005 24702154 9712872 10733106 10706854 12761559 8609214 10854442
CCL13 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9660793
CCL13 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9276730 10733106 9005985 10699158 16339911 22633458 12149192
CCL13 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10477718 9790730
CCL13 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9276730 10699158 24890717 9195948 22633458 12554737 12149192
CCL21 CCR7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11970971 10488147 9507024 10699158 16713569 22633458 22221265 9585422
CCL21 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26888559 11907075
CCL26 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15207250 12689946 22633458
CCL26 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22633458 29637711 15039444
CCL26 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22633458 15039444
CCL26 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 16102831 10488147 15207250 10699158 16339911 22633458
CCL26 CX3CR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22633458 20974991 29637711
CCL28 CCR10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10975800 10781587 22633458
CCL28 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10975800 22633458 12964882
RELA CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 12820969 11478739 17510282 19786024 12050170 21138578 12122011 19828633 18367595 22030901 18502824 16707500 10926836 11413310 20663893 22388040 15144466 9120310 12603855 26096887 11259372 21189258 12388374 15972972 11389171 25523420 18525004
NFKB1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12820969 11413310 11478739 12122011 17065335 17510282 11700023 15144466 19786024 16707500 21189258 12388374 15972972 9120310 11389171 12050170 11259372
REL CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12820969 17705131 11259372 9120310 20058312 16707500
IRF1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10385645 11413310 22292067 17565659 10713367 20861350 15860458 16707500 12388374 12165487 10926836
JUN CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11413310 10760799 19828633 10075858 20862675 26096887 7513046
CCL5 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 16298345 10488147 28381538 10699158 22633458 9289016 12213786 8663314 11449371 10318947 12964882 25923671 9207005 23480650 11116158 10477718 14637022 9334377 9790730
CCL5 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10734056 7622448 8642344 22633458 10733106 10699158 9289016
CCL5 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9660793
CCL5 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10734056 7622448 14637022 22633458 9115216 9624164 10699158 11116158 12270118 7545673 9289016 9336350 10910894 8530354
CCL5 CCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8573157 12270118
CCL8 CCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9115216 10699158 9195948 22633458 12554737 12149192
CCL8 CCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10699158 22633458 9115216
CCL8 CCR5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10477718 9468473 10699158 9790730 22633458 12964882
CCL8 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10699158 9005985
TNF CCR2 â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10623817 10925299 11112697 11438547 11875494 12646658 12811837 1431106 14607933 14625680 15099563 15699106 16713974 17916596 18633355 19411070 20038811 20184663 20435894 21133840 21411734 21826665 22595692 22955274 23170255 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 8910423
CXCL11 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458 15178708
CXCL9 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458
CXCL10 CCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11110785 22633458
CXCL10 CXCR3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 18514095 18922917 22798340 23567181
TIRAP CXCL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 CXCL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LY96 CXCL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK2 CXCL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 CXCL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TBL1X CXCL10 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG CXCL10 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
TBL1XR1 CXCL10 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 CXCL10 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 CXCL10 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
IRF7 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23405030 20483755 16253303 24701034
IRF1 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16253303 19342664 19880820 17167270 24130180 19929594 9858321 24127910 27551049 19541350 9794404
RELA CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23932714 20164184 15226358 16253303 25199798 16982926 19342664 10756005 23740952 17449583 16818736 19929594 22030901 19479051 24257594 21249144 24701034 20833730
NFKB1 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20164184 16253303 17274000 20579762 16982926 19342664 10756005 16818736 19929594 19479051 21249144 24701034
STAT1 CXCL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15006601 25199798 22022583 23153456 23740952 9690917 9858321 24127910 12754213 19479051 20585034 20833730 17558387 19136629 28262979
CXCL10 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 9660793 12571234 10233762 9625760 15761110 12750173 10699158 9064356 16189514 12884299
CXCL11 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 15273303 9625760 15761110 12750173 10699158 16189514 11259614 12884299
CXCL12 CXCR4 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 15261139 15882617 17035340 20535745 20644254 21521526 22025564 23034983 23402812 23567181 24277834
CXCL12 CXCR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24023874 10233851 10699158 11859124 22633458 18648536 18448868 8752280 30476826 12714578 16725153 9712844 8752281 9551924 21757744 19837984 25495026 26582643 16626895
CXCL12 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9660793
CXCL6 CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8702798 10699158 9485196 16189514 9692902 22633458 12964882 10593335
CXCL6 CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 8702798 9485196 16189514 9692902 22633458 12964882 10593335
STAT1 CXCL9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9680354 12403783 20585034 19136629
CXCL9 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9660793 12782716 15761110 9625760 12750173 10699158 11259614 12884299
PPBP CXCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8702798 1427896 8195702 8137938 24335961 16189514 22633458
PPBP CXCR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 8702798 9126332 1427896 8195702 24335961 8550564 10699158 16189514 22633458
PF4 CXCR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21655676 12782716 10699158
STAT3 CXCR4 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
RELA CXCR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20068066 12690099 16267013 20157762
HDAC3 NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 PPARG â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1X â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 PPARG â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
HDAC3 TBL1X â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11509652 11013263 16195251 11931768 16469706 21258344 17694085 10860984 16917504 10944117 23752268 16713569 14527417 11466315 11804585 12628926 15601853
HDAC3 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17015477 16189514 12479814
HDAC3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11533489 16189514 12419806
HMOX1 TNF â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17689680 22461508 23390297 6357187 8871614
JUN HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8774698 24755082 8872603 20486760 20833713 18689604
STAT3 IFNG â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 10347215 12223527 14607900 14670306 15218058 15356132 15573129 16418395 18776941 19380816 20093776 20237412 20406969 20581311 21115385 21840487 23124025 23454751 23953057 24857661 27216177 28186502 7543512
IFNG RELA â—¼   ENZYMATIC_REACTION ✅ 48.0 1.0 ACSN 10485906 10679398 11489965 11579131 11777960 11870632 11964313 12133954 12413632 12759422 12818165 14607900 14668329 15079071 15536066 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17145890 17404308 17550372 17559085 1825141 18272812 19171876 19833085 20038811 20138012 20819927 21149606 21224476 21411734 23430059 24658051 26755705 2965306 6425450 8383323 8580069 8641346 9743347 9834059 9864217
IFNG IL10 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IFNG MYD88 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IFNG STAT1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11489965 11579131 11777960 11830590 11870632 11875494 11964313 12193701 12223527 12413632 12433365 12796776 12811837 12818165 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15634932 15644117 15699106 15778339 15811952 15814715 16127449 16286920 16424049 16713974 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 1825141 18272812 18345002 19833085 19879327 20038811 20819927 21097505 21149606 21263073 21411734 21930765 23390297 24658051 25960930 26755705 2965306 6357187 6425450 7594497 8683106 8871614 9834059 9864217
IFNG LY96 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
IFNG STAT1 â—¼   DOWN_REGULATES ✅ - 69.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11489965 11579131 11777960 11830590 11870632 11875494 11964313 12193701 12223527 12413632 12433365 12796776 12811837 12818165 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15634932 15644117 15699106 15778339 15811952 15814715 16127449 16286920 16424049 16713974 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 1825141 18272812 18345002 19833085 19879327 20038811 20819927 21097505 21149606 21263073 21411734 21930765 23390297 24658051 25960930 26755705 2965306 6357187 6425450 7594497 8683106 8871614 9834059 9864217
IRF2 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12479817 18281489 10859338 10454342
JUN IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20006311 22123848 14734615 15187132 11943142 20304822 17556653 1314139 17105733 22413812 19265145 11801649 16713974 7759501 12836278 15522880 12626576 9558063 8756632 18641343 22351517
REL IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9374532 16481345 23195252 1542667 17012234 7957928
STAT1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 12759422 14735146 26170288 8823363 1833631 8647290 7619083 11416037 12130529 16162660 21178011 9218597 12493643 17283162 15217838 10830295 24200694 7957928 19476491 9271410 19262492 7565811 9880553 17878383 9748323 21039465 17016440 10881178 21530491 17270146 12052885 15055356 10201928 18616672 13678429 19124156 9491997 24478085 8509377 8990168 12893768 16380218 23740952 17105733 16195385 23419754 19935876 7796811 17558024 19929594 10713330 23645984 9548487 11390994 12223098 15931263 17689680 18802113 18787082 10440232 20004484 10373559 10585866 10707961 12403783 23582260 10982806 9059994 16785492 22767256
RELA IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17035338 12759422 12105194 21243522 9374532 10227974 20643337 19929594 19732956 21224476 23195252 23667107 12842891 14662860 12757742 18690006 17407192 10075983
NFKB1 IFNG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12759422 21642544 21243522 9374532 10227974 16481345 17556653 19732956 21224476 14662860 12757742 18690006 17407192
IFNG STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 29796172 23285134 18566411 28430601 28143527 24366643 24608040 17947699 25950470 19846878 27378243 18950705 27570112 15051500 17986321 26467650 23657944 20087684 9649436 22823229 14517275 22178447 22425562 23352233 23562842 28445952 11960596 17997851 24443556 26934444 24777831 11972023 12725866 26113305 22162832 29925830 10707961 23840250 25753288 9454765
MYD88 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LY96 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TIRAP IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK2 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IL10 STAT3 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10433356 10542212 10623821 11207245 11875494 12818165 14607900 14610620 15282297 15579430 16200688 16424049 16713974 17404308 19833085 20184663 21115385 21191065 21220452 21840487 26755705 7512720 7521688 7543512 9834059
IRF5 IL10 â—¼   DOWN_REGULATES ✅ - 9.0 1.0 ACSN 15749884 16243976 16413922 16713974 17404308 17485448 20547845 21240265 23390297
NFKB1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15465827 9310124 19124729 19766270 16835236
STAT3 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21398617 18403020 10903771 25108026 24315995 21157434 12857749 28011648 31886314 18765795 19124156 18848473 12817009 16606674 21385272 21041726 28713870 22378047 15034082 17404037 15972681
STAT1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18292493 19703987 21398617 19124156 20709027 12817009 21041726
RELA IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18760861 9310124 19124729 19122653 18077329 22070873 27324129
IL10 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24513872 20681025 29682323 25512602 19890111 25762897
STAT3 IL17F â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26750311 24412612 16698929 20493732
STAT3 IL1B â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
REL IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8413223 20975042 23195252 19690169 19122653 8910763 14670622 17082635
NFKB1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8413223 17707233 11058167 12686724 16433741 18285351 8021507 9878621 14960579 10963848 9058643 15543947 20696864 8679226 11035101 15972680 20336759 18772363 10080875 17082635
RELA IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 26596471 27338466 11114294 8413223 20975042 17707233 23383347 11058167 12686724 16433741 23667107 15382119 19122653 24009751 27211851 18566416 15292915 20617571 23056550 12517972 18285351 19843519 22267743 15812237 25161822 22388040 8021507 9878621 14960579 10963848 23195252 11395507 27534992 9058643 15543947 19846753 20696864 8679226 24908318 28389361 27371733 15972680 20336759 10080875 17082635
IRF1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11359842 19843519 9754830 20617571 19929594 12759449 26206900
JUN IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11306276 18566416 7935377 10226077 14686613 16365456 11145674 17283046 20463008 23608488 8133045 8798756 18789903 16729332
IL1B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25606026 26999213 22240205 23666959 19197368 25306394 24009751
IRAK4 IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TIRAP IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LY96 IRAK2 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK2 LY96 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 21606490 11544529 17890055 19679662 20485341 17878161 16024789 19224918 20400509
LY96 IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
TIRAP IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 IRAK2 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 IRAK4 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 10679398 11274345 11592085 11964313 12620219 12682231 12907458 14504095 14607900 14660645 14662834 15099563 15749884 15749903 15802534 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 18977329 19161412 20547845 21372296 21826665 23508573 23681101 23811849 26885855 27048821 27066895 9469432 9743347
IRAK4 LY96 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 TIRAP â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 IRAK4 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 10679398 11274345 11592085 11964313 12620219 12682231 12907458 14504095 14607900 14660645 14662834 15099563 15749884 15749903 15802534 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 18977329 19161412 20547845 21372296 21826665 23508573 23681101 23811849 26885855 27048821 27066895 9469432 9743347
IRAK4 TIRAP â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
IRAK4 LY96 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 IRAK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 20485341 15084582 19167362 12150927 17486091 26871637 25502805 24316379 16189514 18221795 15905496 25910212 12538665 16410796 22011580 12860405 12297423 32296183 17507369 11960013 24735611 20966070 17548806 31515488
TNF IRF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
STAT1 IRF1 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT3 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10068671 8647845 9325164 8168491 21723864
STAT1 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 10528163 9218597 10068671 18694960 11752148 17270146 12077266 20825659 24478085 11694349 9307237 8621447 18401423 9806359 22002246 10764778 16140971 19122651 18497060 7678055 8647845 10666420 8168491 9259325 21200019 17558387
NFKB1 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12077266 18694960 17274000 12595462
IRF1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18802049 17725714 23811275 24012417 19805480 10404391 12165487 16931033 26206900
IRF1 IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7630638 7507207 9054665 8152803 15560761 10321737 12493643 1431317
STAT1 IRF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24012417 16512786 10764778 17918184
STAT1 IRF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22951020
IRF5 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18332133 15665823 21240265 20237317 20935208
IRF7 LY96 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14517278 15210742 14703513 9566918 17823124 17157040
NFKB1 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15265881 16982926 11877397
STAT1 IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22951020 11877397 16628196 22252317 12768031 15767254 15664995
RELA IRF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15265881 16982926 11877397
JUN TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 12759366 11087751 7935377 21059644 16881863 24548427 12509451 9826775 10318823 8998076 18408586 15546613 20164416 7896795 9211933 10952728 9566900 23583459 10748079 24009130 10954918 10754326 9813054 10837498 9988757 11739517 16365438 19285436 16199883 8816436 10551799 8552071 9160673 11490006 21098092 16483936 10688670 10913190 16888805 9030359 25567680 9760243
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
KLF4 PPARG â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
TIRAP LY96 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
MYD88 LY96 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LY96 TIRAP â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 LY96 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
LY96 TIRAP â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 MAP2K6 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
MYD88 TIRAP â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
MYD88 TIRAP â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16267105 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
STAT1 MYD88 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
TIRAP MYD88 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 22673208 19506249 11544529 20048342 16410796 21334391 17258210 24316379 25948473 24265315 18221795 12888566 16189514 21873236 11526399 28483816 17583698
PPARG NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1X â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1X â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 TBL1XR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17620012 15060155 15601853 14980219
NCOR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15175761 11877444 15604093 16127449 11903058 22078880 23703729 9121466 21775429 17468099
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17513725 12058956 24337575 12657243 17704137 12471036 17707233 7624137 11259437 12686724 16433741 26114754 20237317 7876168 16707469 12117498 14976218 10485496 15465827 8622636 15812247 21138578 18990758 10748079 15013838 15749903 16916598 17646159 10754326 16040075 10837498 18285351 11675405 11739517 15743782 20066113 20617556 17085785 8530146 8805669 10919279 14960579 1740105 10963848 16055086 9742085 17292554 10553096 11312646 15543947 17442180 16285952 10079106 11297551 10551799 10201927 12907458 8679226 9281604 22782967 8219230 11749970 9916895 11094063 11490006 7895918 1618817 16483936 18057724 20722069 16569682 9452482 17407192 17082635
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
STAT3 OSM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8918689 8559663 16909117 10391682 19404962
PPARG TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG TBL1X â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG TBL1X â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20376096 11009565 14646597 20473515 11124825 17532302 17464333 19031802 14656714
REL TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10201927 17513725 18990758 16997280 7624137 23195252 17012234 11350953 17082635
RELA TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 136.0 1.0 Omnipath 26596471 17707233 20817730 12686724 27075886 21765477 21537341 19530226 17390058 18077329 15064230 20617556 8805669 17351769 23335080 21573233 17292554 16285952 9916895 11749970 7895918 17496784 12628924 23857586 12657243 15857826 12471036 11259437 16433741 9831247 20237317 15465827 26023919 22661093 10748079 15013838 17350185 10754326 15470505 11827962 20139176 26408955 22901690 18772140 21108432 22742857 23195252 18362169 24012417 11312646 17442180 9281604 10079106 11297551 15081318 22718766 24908318 8219230 26004152 11094063 11490006 9916692 16483936 18057724 16569682 22138107 18467438 20547752 22723832 19846753 17407192 20221401 19854828 20534538 7876168 16707469 12117498 20544543 23178569 15812247 21138578 12610112 25888873 16916598 16040075 28039105 14749357 20066113 19285436 25161822 22388040 14960579 20195282 16199883 15543947 23971673 10551799 11290773 22798670 22021035 20722069 20221720 27338466 19385047 12058956 26997758 25690886 7624137 20686703 26114754 14976218 10485496 17607667 8622636 11007957 18285351 10837498 11739517 18719026 17268554 17085785 17142966 10963848 9742085 23042817 27534992 10553096 26516703 20696864 10201927 16850160 8679226 21098092 20097764 9129150 17082635
TNF RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 15192014 27329558 22240205 15833743 19351843 28187781 15841081 28107185 28373828 26999213 24386331 24957606 26179215 21572963 18258304 28317833 29441018 10722927 19596989 28423685 12881425 25118327 24036851 28089769 21904602 24141032 10938077 30201812 20691659 24166907 19789307 19393267 22768286 26310932 19411070 23789107 28790310 29708974 20507904
STAT3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19345327 12057007 23335796 16713569 18448488
STAT1 TNF â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 STAT3 â—¼   DOWN_REGULATES ✅ - 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19122651 17558387 22693070
STAT3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25609649 8662591 12070153 31462771 25241761 11722592 8710878 9794795 23268184 15284024 16189514 9535918 11594781
TBL1X TBL1XR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
TBL1X TBL1XR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
XCL1 XCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 25497737 10699158 10518929 19556286 22633458 11446740 9632725