Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
CASP9 APPL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12011067 11248093
DCC APPL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12011067 11248093
AR APPL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12621049 20610535
APPL1 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12011067
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
AR EZR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 16873375
BCL11A MAP1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19616629 20534004
SRC CACNA1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17942635 12850569
CASP9 CASP3 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 0707715105 18723680
CASP3 CASP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 12011067 15573119
CASP3 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10672017
CASP3 EIF2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10734073
CASP3 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10432301 10734073
CASP3 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11248093
CASP3 EIF2S3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10672017
DCC CASP9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0901767106 19721007
E2F1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12389032 18319725
TRIO CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
TP53 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NTN1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
NCK1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
SRC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
DCC CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
CDC42 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
E2F1 CTSV â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23542171
RRBP1 DCC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NTN4 DCC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0901767106 19721007
WASL DCC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
DCC RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
SRC DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21849478 26323693
WASL DOCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
DOCK1 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DOCK1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NTN1 DSCAM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25754961 18585357
E2F1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18396012
MAPK3 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14967450 22802261
EIF2B1 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15054402 9446619
EIF2B1 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887689 15054402
EIF2B2 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887689 15054402
TP53 EIF2S2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EIF2S2 EIF3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EIF2S3 EIF3E â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
WASL FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11340081 16525419
FYN NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
TP53 MAP1B â—¼   COLOCALIZATION 2.0 0.8 intact 18656471 6700545
TP53 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10529175 9724739
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
NCK1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
NCK1 RPL13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RAC1 NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
NCK1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766742 16189514
WASL NTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
NTN1 UNC5C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804008105 18719102
NTN1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
WASL PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
RAC1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
SRC PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6672010 16291744
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
TRIO RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18212043 18066058
SLIT3 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19741192 30288875
RRBP1 RPL10A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPL13 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
TFAP2A SOX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14969394 12511599
WASL SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
TP53 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18980971 16636674
WASL TRIO â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15040784 10995436
RPS13 RPS24 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RPL5 RPS24 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RPS4X RPS6 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RPS23 RPS24 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RPL5 RPS4X â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL28 RPS24 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL10A RPL13 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPS24 RPS4X â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL28 RPS6 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EIF3E RPS6 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
NCK1 WASL â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
UNC5C NET1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12810718 18719102
EIF3E RPS24 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
EIF2S1 EIF3E â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
EIF3E RPS4X â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
RPS13 RPS6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EIF3E RPS13 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
EIF2B1 EIF2S1 â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 15054402
RPL28 RPS4X â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EIF2S3 RPS6 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
EIF2S3 RPS24 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
RPL13 RPS6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RPS23 RPS6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
TRIO DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
RPL5 RPS13 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
EIF2S3 RPS10 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
RPL10A RPS4X â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
EIF3E RPS23 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AR SRC â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
EIF2S1 RPS6 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
EIF2S2 RPS13 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
RAC1 TRIO â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
EIF2S1 RPS24 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
EIF2S1 RPS4X â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF2S1 RPS13 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF2S2 RPS24 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF2S2 RPS6 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF2S2 RPS4X â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF2S1 RPS10 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CASP9 CASP3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1067155 11242052 11230124 18723680 25241761 15941357 17437405 8900201 15507451
RPS24 RPS6 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EIF3E RPS10 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
APC CDC42 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17145773 21311754
RRBP1 DISC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29961565 31413325
DOCK1 SRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17474147 12615911
EIF2S3 RPS13 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
EIF2S3 RPS4X â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
RPL13 RPL5 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RPL13 RPL28 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PTK2 PTPN11 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
CASP3 CASP9 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SIAH1 SIAH2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EIF2S2 RPS23 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF2S2 RPS10 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EIF2S1 EIF2S3 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PTK2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
NCK1 FAK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8879209 11950595
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
SRC RASA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11389730 16189514 16713569 1717825
SLIT2 ROBO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10102268 17848514
EIF2B4 EIF2S1 â—¼   GTPASE_REACTION ✅ + 0.88 0.88 Signor 15054402
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RPL10A RPL5 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
CASP9 DCC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16537496 11248093 19721007
SIAH1 DCC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31413325 9858595 16713569
MAZ DCC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11527412 12509857
DOCK1 RAC1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
SRC FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16966330 31980649 28514442 19711372 9169421
RPL28 RPS13 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
DRAXIN NTN1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
RPL28 RPL5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RPS13 RPS4X â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
SIAH1 APC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11389840 25241761 16713569
APC CASP3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 10200466 17297457 9973322
AR CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22038727 20610535 23554843
FYN DCC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
SRC DCC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
NET1 DCC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19721007 12810718 26190107 9950216 20434207
E2F1 DCC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12629508
TP53 DCC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15843459
MYO10 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21642953 17237772
DCC MYO10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21642953 17237772
E2F1 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20187294 18627426
EIF2S1 EIF1AX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 641056 592399 429297
EIF2S3 EIF1AX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 641056 592399 429297
EIF2S2 EIF1AX â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 641056 592399 429297
EIF2A EIF2S2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EIF2B1 EIF2B2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10805739 21795329 9446619
EIF2B4 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16288713 8887689 15054402
EZR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11468295 16189514
FBP1 PTK2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NTN1 FYN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK1 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK1 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
MAPK3 RAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17202194 15657136 21419341
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
NCK1 RASA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16189514 10508618 21664272 9233798
NTN1 SRC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
RPL10A RPS13 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
RPL10A RPL28 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
EIF1AX EIF2S3 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
EIF2S3 RPS23 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ROBO1 SLIT3 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
PTK2 SRC â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
EIF1AX RPS10 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
EIF1AX RPS4X â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
EIF2S1 RPS23 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EIF1AX EIF2S2 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EIF2B1 EIF2S3 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
EIF2B2 EIF2S2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
EIF1AX EIF2S1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
FAK1 DCC â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 20434207 28701345 15494733
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
RPL28 RPS10 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
EIF1AX EIF3E â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
FAK1 FYN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11278857 31413325 12558988 16713569 32707033
SRC FAK1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11927607 22402981 7997267 12387730 12558988 23242524 26264872 8941336 16291744 15987550 32814053 9822703 16713569 9507031 17525734 21855630 7529876 11119718 16966330 23065768 8816475 25814554 16189514 11104793 10085298 10931187 8054685 25241761 12615911 21034468 11980671
WASL CDC42 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 31871319 16293614 9422512 10781580 20936779 21311754 10724160 11943145 11331876 15834156
ROBO1 SLIT2 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
EIF1AX RPS6 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CDC42 WASL â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
EIF1AX RPS24 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
EIF1AX RPS23 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
EIF1AX RPS13 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RPL38 RPS10 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RPL23 RPS10 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPS10 RPS24 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
MAP2K2 MAPK1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL10A RPS10 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL13 RPS10 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL5 RPS10 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS10 RPS23 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS10 RPS6 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
EIF2B2 EIF2S3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPL10A RPL28 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL13 RPS24 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL28 RPS4X â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL28 RPS24 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL28 RPS13 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL38 RPS24 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
DCC NTN1 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
EIF2B1 EIF2S2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
WASL NCK1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 16595635 26496610 11340081 26871637 17474147
RPL5 RPS24 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EIF2B1 EIF2S1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL10A RPS24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPS24 RPS4X â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPS10 RPS4X â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPS10 RPS13 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPL13 RPL28 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPS24 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPL28 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPL38 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL38 RPS23 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL38 RPS4X â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPS23 RPS24 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF2B2 EIF2B4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF2B2 EIF2S1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL10A RPL38 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13 RPL38 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPS23 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPL38 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL28 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL38 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL38 RPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPS4X â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPS13 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS13 RPS24 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPS24 RPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL10A RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPL23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL13 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL5 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS13 RPS23 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL23 RPL5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL38 RPS13 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL5 RPS23 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS13 RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS23 RPS4X â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS23 RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS4X RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
E2F1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21966451 17178887 22508987 21099110 21099103
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19305643 10454563 18687691 17108144 17079466
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
CASP3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8626669 9535906 16713569 9208847
SRC AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 28144231 15062576 20570899 25133482 21318111 11032808 25950519 21512132 17525795 12933816 20383201 24728074 24948875 24868554 25547388 19117998 21956655 17045208 15027889 24859991 15466214 26829214 21886458
TP53 CASP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 22154326 22178888 23677569 15578696 17363498 24098340 18064040 23527225 10893263 21859835
CASP3 DCC â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 11248093 16158190 15310786 9796814
E2F1 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18660752 12389032 18319725
CASP9 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10708865 9390557 10508159 11230124 18723680 15657060 16977332 15507451 1067155 9708736 25241761 8900201 11242052 9765224 17437405 19788417 9812896 12620238 15941357 12181739 19465923 12792650 15725726
CASP3 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10224094 9463408
MAP2K1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12792650 18669648
MAP2K2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12792650 18669648
MAPK1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 44.0 1.0 Omnipath 15547943 20080742 12040186 18083711 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 16888006 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
MAPK3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 15547943 20080742 29416675 12040186 15173823 12697810 11940578 19081073 19586613 16227978 12738796 16039586 17466630 17255949 18669648 15187187 19016842 19541618 19091303 19565474 17052211 18039929 18775330 10601235 12792650 11431469
CDC42 DOCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15710388 15247287 12134158 17196961 17027967
SRC CDC42 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
SRC CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14506284 26816343 9626657
CDC42 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17145710 10559936 11331876 10940259 9422512 11943145 10511705 15020669 8625410 11340065 10219243 15003621 15834156 16293614 20936779 10934474 11413130 15713627 11950587 10724160 10467124 10781580 11248548 18719708 10613909 10461188
TRIO DCC â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NTN1 DCC â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11248093 11989976 17613518 17959595 19543238 19931333 20173780 20495383 22920895 26618107 9765224
DCC DOCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NTN1 DCC â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11248093 11989976 17613518 17959595 19543238 19931333 20173780 20495383 22920895 26618107 9765224
NTN4 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19721007 17174565
FYN DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15557120 21849478
NTN1 DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19721007 8861902 26190107 9950216 11239160 25881791 10399920 12810718
DCC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15494733 29479476 20434207 15494734
FYN DOCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NTN1 DOCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NCK1 DOCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
DOCK1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 15723800 15247908 9808620 25533347 10592173 12134158
TP53 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21715977 20805247 8557038 11795482 17210690 22952705
E2F1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22241525 8557038 15706352 21441950 12675512 23954287 12625370
E2F1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22480684 11739724 12625370
EIF4E EIF1AX â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S1 EIF2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2B1 EIF2B2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2B1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2B1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2B1 EIF2B2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2B1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2B1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2B2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2B2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2B2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2B2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2B4 EIF2B2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25910212 10805739 31515488 16189514 32296183 9446619
EIF2B4 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16288713 15054402 16189514 9446619
EIF2S1 EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF4E â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S1 EIF2S2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S3 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF4E EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
EIF2S2 EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2S3 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF4E EIF2S3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
SRC EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16438931 22397367 14504278 25231728 21818323 24339867 15623525 18701134 22262457 24385580 18078820 28306714 15647376
TRIO FYN â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
FYN PTPN11 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
NCK1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10212213 11157475 16713569
FYN PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11369622 12558988 15494733 20151426 12590707 16293639 7505391 15728464 11278857 16713569 10753828 15494732 10085136 15494734
RAC1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
MAPK1 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
RAC1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17496910 18000759 15574420 19151919 11777939 18855897 21614932 12738796 11274345 12040186 19568798 14585353
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
MAP2K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 21675959 11704645 9694850 17081983 7565670 12750173 19690332 12932319 11823456 18799465 15592455 11337027 18083107 21365009 12788955 11134045 19219045 17389395 9447970 15342917 23331499 19534553 17569879 7559390 23047924 8226933 8223433 17272394 15851026 15811950 19494114 18988627 18669648 11549292 23519423 19541618 18691976 1381507 16293107 17906627 11986622 19933846 8376945 19053285 16094384 11971971 17192257 11136732 11948414 8388392 7898932 9731057 11730323 18039929 11118451 19369195 12920017 15951569 15466214 10746662
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 MAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11809795
TRIO NCK1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NCK1 WASL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11340081 26496610 17474147
TRIO NTN1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
NTN1 UNC5B â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12598906 17703233 18582460 19543238 20173780 20495383 21172653 22920895
NTN1 UNC5A â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 16829956 18582460 19543238 20173780 20495383 21172653 22920895
NTN1 UNC5B â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 12598906 17703233 18582460 19543238 20173780 20495383 21172653 22920895
NTN1 UNC5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10399920 12810718
NTN1 UNC5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23599441 26840727 9126742
NTN4 UNC5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12598531 17174565
TRIO PTK2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262
SRC PTK2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11476890 12531888 16919435 17496910 17517963 20027185 25572304 26552706 27216177 8892616
TP53 PTK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24809783 20515733 21355845 21071137 21269258 18493017 17999388 17725966
SRC PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 216.0 1.0 Omnipath 27351421 23242524 16254240 12370821 21940449 26142360 17525734 10593973 14604860 17389395 19171305 22402981 19339212 22353809 9748249 8941336 17570479 12464388 25226367 15611085 15817476 25241761 26393679 27978555 26833789 11927607 17828307 25913180 26866924 15247219 10085298 12387730 19055942 9507031 21454698 10973994 32814053 21057587 27931517 27438371 18793427 19695571 15735019 18560762 10592173 25319025 24389213 21852560 26689988 14984767 7505391 19568240 20103658 20822514 25868388 23275294 28423510 23764511 19625610 15561106 17192257 19138410 19369195 17088251 12753909 28701735 29190494 17016520 15598735 18814847 11821402 11418135 15728464 16291744 25067788 11602246 16713569 22287273 9032297 7997267 12960434 11369622 20616959 26079101 19534553 10931187 22710722 20068231 25866790 21347260 9822703 28202937 16153436 11980671 21855630 19826415 18464795 7529876 20621036 9330873 21473875 9425168 28956212 12615911 15951569 25814554 12876384 17438336 15212693 16966330 20705914 20847951 23729178 20407018 12558988 25127991 25918719 12590707 16360410 8054685 18814027 11696015 22800863 17117420 12495636 11278488 9864370 21776383 18083107 22814579 22194915 20515733 11119718 9148935 10428489 15743500 20655298 23065768 28213315 26923073 24015220 17289681 12110680 22006118 24164353 23109003 18935208 10753828 18233957 8816475 25118939 19664994 25530216 16760434 9330875 21266176 21034468
TP53 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18431400 25241761 15855171 18206965 19857493
PTPN11 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23335101 7589239 10082579 21726809 14572662 15561106 8986614 16189514 10655584 19698715 16920701 15598735
PTK2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 22163037 26816343 29036929 34252134
PTK2 TRIO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12551902
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
TRIO RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9464532 8643598 10798395 32203420 10847683 11595749 21422296
SRC RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22163037 17991704 21798346 26816343 29036929
SRC RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11389730 1717825 16713569
SLIT2 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17848514 10102268 31217826 1010226810102260
SLIT1 ROBO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21600986 10433822 16713569 14761655 1043382210433820
TP53 SIAH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20181957 20421190 14985507 11852084
TP53 SIAH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12077306 12438652 14985507 15326481
TRIO SRC â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15788770 11817894 18212043 18066058 12149262