Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CCNA1 CDKN1A â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CDK2 RBBP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25558984 22231403
SOX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
PPARG CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15041706
DDAH2 TRIP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
E2F1 TK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
E2F1 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
RBBP8 PIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDKN1A CCNE1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 16765349 5218735
FANCM PRKAB2 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
E41L2 ICLN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
E41L3 E41L1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 24366813
E41L2 E41L1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOX2 DDAH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CCNA2 CCNA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDAH2 ICLN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
E41L3 E41L2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24366813
DDAH2 E41L3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDAH2 E41L1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDAH2 E41L2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDAH2 OGT1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDAH2 DDAH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDAH2 HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CCNE1 CDK4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9716181 28205554 28628118
CDK2 TFDP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 33961781 9199321
HCFC1 E2F1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20622854 17612494
XRCC4 TK1 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
E41L3 ICLN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16368544 24366813
CCNA1 E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16774918 10022926
E2F1 CDK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11245432 7969176 8458319 1530885 9199321
CCNA2 E2F1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CCND1 CDK2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
DDAH2 MAP3K20 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
OGT1 HCFC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21285374 20200153 12670868 22939629 21295698 32994395 27705803
ANXA7 CDK4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA7 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ATP1B1 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
E2F1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 7969176 8458319 9724724 12501191
CCND1 TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
SOX2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18456656 25482558
CCNE1 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12006580 11420722 9315635
CDC73 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDK2 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12006580 11420722 9315635
CDK4 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDK4 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDK4 TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
CDKN1A DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
TFDP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10029406 10702805 9191053
RPS6KA1 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TNFSF11 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RAP1B DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNAJB11 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TSC22D1 DDAH2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 MKNK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 PIN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 TAF1D â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 STK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 RPS6KA5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 GADD45G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DDAH2 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HCFC1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17612494 19763085 23629655
E2F1 TNFSF11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18381203
E2F1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15711575 12110166 18319725
CCNA2 CDKN1A â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
XRCC4 DDAH2 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
CCNA1 CDKN1A â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
TFDP1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
CDK2 CDKN1A â—¼   PHOSPHORYLATION ✅ - 0.95 0.95 Signor 15964852
CDK2 CCNE1 â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 19561641
CCNE1 CDKN1A â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
HCFC1 OGT â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
CDKN1A CDK2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16765349 5218735
CCND1 CDKN1A â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CDK4 CDKN1A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
E2F1 TFDP1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CDK2 CCNE1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 8978686 23455922 15980415 24771265 15670215 15514162 26496610 20837141 25728284 9891079 33854239 10330164 8867812 23602568 14681455 11433299 16431923 9716181 20587660 28137908 14701826 14536078 17361108 33854235 10827081 8662825 9472014 25852190 16223725 9192873 11940657 12839982 11132966 10359664 7799941 21092281 8647086 8756624 19631451 28514442 21372285 9660939 17431037 17254967 29439025 19470470 21241890 9840943 17970072 1388288 18559665 12800980 15004009 26186194 24358021 23853094 12529437 15557281
FANCL FANCM â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK2 CDKN1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNE1 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDKN1A CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12383116 25241761 8756624 29997244 16982699 7478582 10022926 32814053 15232106 16009130 16189514
CCNA1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17660363 15840440 16135794 18590585 7575488 17303408 9736735 15133492 15558010 15123636 9556498 10022926 16213134 11980909 16123593 11739724 15279786
E2F1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7623816 11264255 9178900 20580656 14681231 10594784 24335704
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CDKN1A CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 23443559 26186194 21308745 9660939 8756624 15890360 9380407 8242751 8662825 12947099 9632134 17679094 26496610
CCNA2 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15840440 16135794 9736735 15133492 15558010 15123636 9556498 16213134 11980909 16123593
CCNA2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15840440 16135794 9736735 15133492 15558010 15123636 9556498 12501191 16213134 11980909 16123593
E2F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10504464 7929342 22768064 19876926 20220142 9584162 17998543 20655656 8618861 8137237 23078099 23543735 10594784
PPARG CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23455892 18927468 14764597 15486348 11287611 20651819 15041706 19075513 15193259
CDKN1A CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 26203195 23443559 17145710 25416956 7478582 9837900 21988832 21516116 7777546 15232106 16082198 27107012 15695403 8657154 8242751 23007395 9106657 12383116 17556661 8756624 8662825 31515488
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CCND1 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
E2F1 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 21653699 19564413 20220142 23518498 8668155 7623816 1059478 14618416 20410059 12565705 17471231 23543735 10594784 24335704 22185819 21454377 11526499 10504464 8618861 8649818
TFDP1 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18687693 14618416 12029633 10756032 24335704
CDKN1A CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 23443559 31831640 21988832 9472014 17293600 11438644 9380407 12839982 16765349 9632134 25241761 8891332 9660939 8242751 9218599 11477082 8756624 8662825 8637717 9716181 13678583
CDK2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 17145710 16223725 21092281 15004009 10962581 9840943 8643455 24358021 8861947 21372285 17570479 11237742 10330164 22558078 10652300 19561641 10477583 18691976 23853094 12144826 10500095 1388288 10827081 17970072 28137908 19470470 8756624 10809788 14536078 15364936
CCNE1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7575488 18590585 18687693 9315635 17303408 17660363 12006580 11420722 15279786
CDK2 E2F1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12086603 14536078 14988723 15136767 15147722 15175241 15279786 15798197 16713580 16805667 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18469862 18590585 18636226 18995830 19282663 19342888 19622404 19793801 20051983 7575488
CDK2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 7575488 18590585 9315635 17303408 17570479 25101673 16213134 17660363 12006580 11420722 15279786
CDK2 TK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 25003822 12435275 14697231 9575153
CDK2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 94.0 1.0 Omnipath 23443559 23455922 10878006 20100570 23602568 15964852 20839231 25416956 23737759 9840943 18850315 11302688 20519948 24358021 19440234 15557281 9472014 9658399 16962592 9736735 12949733 8641969 10022118 15890360 12839982 16765349 17418410 15647383 10874474 15232106 17570479 17698606 12361598 26496610 9632134 24419005 12417722 16189514 26186194 20587660 25241761 8622677 9660939 25483090 12800980 20102411 10918595 12058028 12144826 8242751 9464540 9858587 29899857 23007395 11477082 9218599 12383116 25463440 12730199 8756624 9284049 9380407 9546435 24218572 16964243 15212693 13678583
CDK2 RBBP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23623683 33097710 27308383 24236237 19202191 24982848 25956864 22743550
CDKN1A CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 23443559 15169570 18850315 9658399 16962592 15232106 9632134 16189514 8622677 15695403 20102411 8242751 9464540 23007395 7626805 9106657 12383116 30193583 17556661 23543736 8756624
CDK4 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
CDK4 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
E2F1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9748148 9191053 16923815 17008321 10030670 10702805 15048076 17167174
PPARG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19551868 19103521 19208833 16985067 18509005 15041706 15345676 16091736
CDKN1A E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CDKN1A TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
CHEK2 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 22558186 27679857 15140942 12717439 23219173 19473886 20860841 15838517 20603083
E2F1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15711575 12110166 20971808
E2F1 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 20211142 15133492 22327218 7892279 16360038 9199321 8405995 9704927 8816798 9780002 8657117 9464260 22629304 7739537 27705803 25368385 9501179 8816502 8832394
FANCM FANCL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM FANCL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
RAD18 DDAH2 â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
RAD18 ACTN3 â—¼   KO_UP_REGULATES ✅ + 1.08 1.08 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368