Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 SVIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ARPC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
CHFR PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18172500 23268447
PFN2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GRB2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TP53 DLST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17916908 21191025
SPRED1 DTX3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TRAF4 FAM90A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GRB2 FLNB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
FLNB UBE2L6 â—¼   COLOCALIZATION 2.0 0.8 intact 19270716 7288582
FLNC GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 SPTBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SLC25A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPS8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPS13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RPL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUFM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HNRNPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
NOTCH1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330899 22363130
UBE2L3 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24979766 26216882
XIAP RAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22117219 8313544
SPRED1 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 TRAF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788948 16969126
TP53 TRAF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788948
CHFR UBE2D2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
FAM90A1 SPRED1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
RPL4 RPS13 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA1 HNRNPH1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DTX3 GUAD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DTX3 NDUS6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DTX3 SYFB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
PRKDC MK09 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22366412 11749722
DTX3 RN114 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DTX3 NDUF5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33403043 26186194
DTX3 NMD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DTX3 ITSN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DTX3 NARFL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RPL7 RPS8 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
TRIM21 UBE2D2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
GRB2 MK09 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7642542 9019171
PRKDC PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20085707 16794079 21575865 9398855
GRB2 FLNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21706016 17474147 12577067
RPL4 RPL7 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
SVIL FLNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 20309963
FLNB FLNC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22863883 19293945
RPS13 RPS8 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
DTX3 MK09 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 26186194 32296183
CHFR DTX3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22493164 26186194
UBE2D1 XIAP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
NMD3 RPL7 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
NMD3 RPL4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CHFR PARP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
FLNA FLNB â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
UBE2D2 XIAP â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
RPL7A RPS13 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RPL7A RPS8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
RPL4 RPS8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
UBE2L6 FLNB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19270716 12582176 16009940
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ITSN1 UBE2K â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
UBE2L6 UBE2E1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16112642 16428300 16122702
RPL7 RPS13 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ATP5A1 ATP5B â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
RPL4 RPL7A â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HNRNPA1 HNRNPH1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
TRIM21 UBE2E1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
RPL7 RPL7A â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
RNF38 UBE2D2 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
NMD3 RPL7A â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
FLOT2 SVIL â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
FLNB FLNA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12393796 22939629 26496610 26344197
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EEF2 RPS13 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 GNB2L1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPS8 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
GNB2L1 RPS13 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
EEF2 RPL4 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPL12 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPL7A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPL7 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
GNB2L1 RPL4 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
GNB2L1 RPS8 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
GNB2L1 RPL12 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
GNB2L1 RPL7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GNB2L1 RPL7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL7 RPS13 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL12 RPL4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL12 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7 RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7 RPL7A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS13 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL7A RPS8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS13 RPS8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATP5A1 ATP5B â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 10838049 11410595 11744738 12110673 14701807 14757859 18953340 22841746
ATP5A1 ATP5B â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 10838049 11410595 11744738 12110673 14701807 14757859 18953340 22841746
PRKDC HNRNPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27303920 25986610 19351595 25030905 19844162
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
MAPK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 12356735 14665630 26158765 18778462 12969974 12861053 15254178 17135248 18669630 12384533 17363488 17698850 11283254 10706102 21454683 18931691 11551930 11397945 14612532 15064747 15963507 11175334 11423984 27147566 29234486 24657168 10581258 14517211 17353187 10673500 22030623 14527925 22728651 17525747 15629715 9393873 11447225 15671037 22285752 17245430 15140942 28673515 23871434 11078726 20041275 11896587 16731759 17121812 33514736 11861384 25431954 12810724 17967874 12955074 21832239 16818520 12756247 23798621 11526498 20009884 16713569 10202145 11850826 11896572 10710310 10570149 12959929 15269203 11583595 21148320
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
TP53 FLNC â—¼   KO_UP_REGULATES ✅ + 1.04 1.04 PKG 28854368
PARP1 CHFR â—¼   KO_UP_REGULATES ✅ + 1.19 1.19 PKG 28854368
TP53 NOTCH2 â—¼   KO_DOWN_REGULATES ✅ - -1.32 1.31 PKG 28854368
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368