Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H2AX UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
DZIP3 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RAD18 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TOLLIP ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PRRC2A ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
R3HDM2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBE2I ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
NCOR1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
UBE2V1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2E3 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PUM1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
BECN1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BECN1 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
UBE2I CARM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
DAZ1 DZIP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216016 12511597
SPTAN1 DZIP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MATR3 DZIP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DZIP3 SSRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18206970
PPP1CA HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17008050
UBE2D2 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBE2D4 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 TOLLIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 TRIM21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 UBE2E3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2N UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
RNF11 UB2D2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 14562029 32296183 15231748 19549727 19690564
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
H2AW SSRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DZIP3 TIAR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 32460013
BRCA1 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25184681 29656893 23901102
HNRNPF HNRNPH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
BRCA1 UBE2E2 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
BRCA1 UBE2E3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
BRCA1 UBE2E1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
TRIM21 UBE2D2 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ATX1 DZIP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24326307 32814053 16713569
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
BRCA1 UB2D2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21113135 19712108
HNRNPF HNRNPUL1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DZIP3 UB2D2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19549727 18206970
CCND1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9244350 16713569 17334399
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
BIRC2 UBE2D1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
BRCA1 UBE2D1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
DZIP3 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18206970
H2AX BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18344987 12419185 26095369 20681793 19805520 18001825 31501894 26121674 10959836 12485996 18001824 19766185 11927591 34321665 29499138
UBE2N H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17709392 18077395
BIRC3 UB2D2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12525502 11724934 22902369 25275296 29191979 21113135 21393245 18784070 16547522 11907583 23871895
UBE2E1 ATXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18439907 25641559
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
HDAC1 RUNX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18430739 22274925 18850007
UBE2N HERC5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16112642 16428300 16122702
UBE2D3 MEX3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UBE2N RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
UBE2V2 RAD18 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18719106 18316726 19723507
BRCA1 UBE2D3 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
H2AX SSRP1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 24981860 28514442 18406329 16522924
TRIM21 UBE2E1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
RNF11 UBE2D1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
TRIM21 UBE2N â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
RNF38 UBE2D2 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RNF11 UBE2D4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
BIRC2 UBE2D2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
BIRC3 UBE2D2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
BRCA1 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18001824 18001825 17145710 12419185
DZIP3 ATXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 32814053 16713569 24326307
PPP1CA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 25056273 12438214 17511879 17603999
UBE2D3 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 11927591 21531767 16713569 21756275 12732733 22863316 17349954 21113135 25355358 21532592 18369654 16818604 20351172 15905410 16628214 19712108 21965653 15886201 15367667 23246971 12438698 17283126
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
RUNX3 RUNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17488194 15688019 19403666
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
RAD18 UBE2N â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
RAD18 PPP1CA â—¼   KO_UP_REGULATES ✅ + 1.72 1.72 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368