Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAD51C GEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
XRCC3 GEN1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24076221 24831703
RAD51C TOP3A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
XRCC3 TOP3A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 24509834 23509288
GEN1 PCYT1B â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
GEN1 UAP1L1 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
GEN1 DCD â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
GEN1 LGALS1 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
GEN1 PEX16 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
GEN1 ZNRF2 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
GEN1 HERC5 â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
RAD51C XRCC3 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
FANCM MSH6 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
FANCM LGALS1 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
FANCM TOP3A â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
FANCM TOP3A â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 12535671 12972610 16697054 18550849 18931676 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
GEN1 CADPS â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
GEN1 ANK1 â—¼   KO_DOWN_REGULATES ✅ - -1.1 1.09 PKG 28854368
GEN1 DPP7 â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
MSH6 DPP7 â—¼   KO_UP_REGULATES ✅ + 1.35 1.35 PKG 28854368
GEN1 ANXA1 â—¼   KO_DOWN_REGULATES ✅ - -1.42 1.41 PKG 28854368
FANCM SERPINB9 â—¼   KO_DOWN_REGULATES ✅ - -1.64 1.63 PKG 28854368
FANCM DPP7 â—¼   KO_DOWN_REGULATES ✅ - -1.65 1.64 PKG 28854368
GEN1 SERPINB9 â—¼   KO_DOWN_REGULATES ✅ - -2.1 2.09 PKG 28854368
MSH6 MSH6 â—¼   KO_DOWN_REGULATES ✅ - -5.12 5.11 PKG 28854368