Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
KSR2 BRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22510884 8396417
M3K8 MP2K1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16291755 8631303 12832462
MYC 1433B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
1433G KSR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RASK 1433Z â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 34079125
RASK 1433E â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 34079125
RASK MP2K1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 31980649
MYC 1433E â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
ARAF HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29777862 31980649
MP2K1 HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17979178 27684187
MYC HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC 1433T â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
1433T HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25277244 20618440
1433T FIBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433T KSR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FIBB MP2K1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MP2K1 HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 31980649
RNAS9 MP2K1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MP2K1 LTOR3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 9733512 11266467
BRAF HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 31980649
HSP7C MP2K2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31980649
NUFP1 MP2K1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HSP7C 1433T â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15324660 27684187
MYC MP2K1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26496610 7957875
MYC HSPB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
MP2K2 1433F â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
MP2K2 1433T â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
MP2K1 1433T â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
BRAF M3K1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16888650 16810323
PPARG MP2K1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21690289 17101779
MK03 MYC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9155018 15210690
1433B MP2K2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10409742 24255178 32707033 31980649
1433B ARAF â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31980649 25852190 24255178 32707033 29777862
KSR2 1433G â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27086506 32707033 33961781
1433G MP2K1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033 31980649
KSR2 MP2K2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27086506 32707033 33961781
KSR2 1433E â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27086506 32707033 33961781
1433F MP2K1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033 31980649
RAF1 HSP7C â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16093354 20039095 31980649
ARAF 1433T â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25852190 32707033 29777862 31980649
MP2K1 1433E â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17979178 31980649
YAP1 MP2K1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24211253 27684187
YAP1 1433B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17974916 31501420 25796446 24255178 27684187 24366813 20048001 30472188 28514442 19439659
MP2K1 1433Z â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17979178 27684187 31980649
1433F KSR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 17979178
BRAF HSP7C â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17979178 27684187 31980649
MP2K1 M3K1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 14500727 10969079 17110930
ARAF RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 34017080 20130576 31980649
ARAF BRAF â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MP2K1 1433B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31980649 24255178 10409742 17979178 32707033
1433Z HSPB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15161933 25277244 20618440
JIP3 RAF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10523642 11044439
MP2K1 MP2K2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 10409742 32707033
BRAF 1433E â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 31980649 27684187 27034005 28514442 17979178 32707033
YAP1 1433E â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26933062 25751139 25796446 24255178 27684187 24366813 30472188
1433E ARAF â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25852190 29777862 19608861 20936779 17979178 32707033
BRAF 1433F â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 31980649 27034005 28514442 17979178 32707033
MYC MK01 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7957875 31638140 29467282 15210690 9207092
1433B KSR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 24255178
1433G 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15324660 26344197 26496610 28514442 22863883 17979178
1433G 1433T â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15324660 17085597 28514442 22863883 20618440
1433F 1433Z â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 26496610 28514442 22863883 17979178 20618440
1433Z 1433T â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 28514442 22863883 20618440
BRAF MP2K2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 31980649 24746704 27034005 28514442 17979178 32707033 25600339
BRAF RASK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 31980649 30194290 27684187 27034005 28205554 28628118 28514442 34079125
1433T 1433E â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 31980649 20936779 21988832 17085597 28514442 17979178 20618440
1433E 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31536960 33961781 26344197 31980649 26496610 7615088 20936779 28514442 22863883 17979178 12507503
1433E M3K1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9452471 14743216
RAF1 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16093354 31980649 25852190 10620507 26496610 11969417 11697890 8702721 16041367 28514442 17979178 32707033
YAP1 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25751139 26933062 25796446 24255178 27684187 24366813 30472188 28514442
1433F ARAF â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25852190 26496610 29777862 11969417 28514442 17979178 32707033
1433F 1433T â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 28514442 22863883 17979178 20618440
PEBP4 MP2K1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15302887 19197339
KSR2 MP2K1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27086506 12975377 32707033 33961781
PEBP4 RAF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15302887 19197339
1433B BRAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15324660 31980649 17353931 24255178 27684187 12620389 27034005 10931830 28514442 32707033
1433B RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16093354 7644510 11697890 24255178 8085158 16041367 32707033 7882972 19595761 25852190 10620507 12620389 8702721 7935795 28514442 16189514 12360521 31980649 10848612
YAP1 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15324660 17353931 25796446 24255178 27684187 28205554 28628118 24366813 28514442
1433E 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26344197 31980649 20936779 21988832 17085597 28514442 31536960 17979178 12507503
1433Z 1433G â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31536960 33961781 26344197 26496610 28205554 28628118 28514442 22863883 20618440
1433G BRAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15324660 31980649 17353931 27684187 27034005 28205554 28628118 28514442 17979178 32707033
1433G RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 10433554 16093354 31980649 17353931 25852190 10620507 11697890 28205554 28628118 8702721 16041367 28514442 32707033 16189514
1433G ARAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15324660 31980649 17353931 25852190 28205554 28628118 28514442 32707033 29777862
1433Z ARAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25266655 19933840 31980649 25852190 20052757 20936779 28205554 28628118 32707033 29777862
1433Z YAP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 15161933 33961781 29069755 25670079 24255178 27684187 28205554 28628118 30472188 26578655
1433Z BRAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15161933 15324660 31980649 17353931 26496610 27684187 27034005 28205554 28628118 28514442 17979178 32707033
1433Z RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14688280 16093354 16306228 10887173 9153224 9261098 11697890 15664191 7628630 20052757 10611249 8085158 28628118 7939632 16041367 17979178 12861023 32707033 25852190 10620507 7935795 8601312 9632690 31980649 20679480 19049963 28205554 22222486
MP2K2 ARAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11909642 32296183 31980649 25852190 24746704 21988832 32707033 16189514
1433E RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16093354 15459208 31980649 25852190 7644510 19608861 11697890 8702721 16041367 17979178 16189514 32707033
YAP1 1433T â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15161933 31619268 31501420 25796446 24255178 27684187 22863277 12535517 16713569 24366813 28514442
1433T BRAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18332145 31015455 15324660 31980649 17353931 27684187 27034005 28514442 17979178 32707033
1433T RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8663231 7760835 16093354 31980649 17353931 25852190 10620507 7479742 15618521 11697890 10757792 16041367 28514442 32707033
BRAF MP2K1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25155755 26496610 25600339 20212043 18332145 27684187 32707033 17979178 9733801 19371126 16888650 28514442 23934108 31015455 16810323 31980649 24746704 27034005 25437913
ARAF MP2K1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24114843 8621729 8157000 31980649 26496610 24746704 8394352 17979178 7731720 32707033
BRAF ARAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 31980649 25241761 20130576 28205554 28628118 28514442 34017080 17979178
MYC RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 17314511 28628118 9315742
MK01 M3K1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 14500727 14581471 10969079 24135036
KSR1 1433Z â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 33961781 28514442 9115393 9858547
MK01 RAF1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 16093354 10958680 19058874 11409918 15664191
MK03 RAF1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 9446616 19058874 11409918
BRAF RAF1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
JIP3 MP2K1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11044439 10523642
RAF1 MP2K2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11909642 8157000 31980649 8393135 24746704 16364241 19058874 21988832 9671314 16189514 32707033 9808624
KSR1 MP2K2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 27086506 11909642 32707033 31980649
KSR1 MP2K1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 18332145 15520859 11741534 31980649 27086506 11940661 26496610 15090600 17979178 32707033
MK03 MK01 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 31980649 23397142 16424009 19058874 23602568 32707033
MP2K2 MK03 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8626767 7687743 9006895 8226933
1433G 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 15324660 24981860 26344197 24255178 17085597 28514442
1433F 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 26496610 24255178 28514442 17979178
1433T 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24255178 17085597 28514442 22863883 20618440
1433Z 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 26496610 24255178 28514442 31536960 20618440
1433B 1433E â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 31980649 24255178 30135474 20936779 17085597 28514442 31536960 17979178 12507503
1433Z 1433E â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19766566 31536960 33961781 26344197 31980649 22939629 26496610 20936779 21988832 28514442 22863883 17979178 20618440 16376338
RAF1 BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8396417 22510884
MK03 MP2K1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8626767 8226933 10748187 19197339 9733512 19058874 34497368 9006895
RAF1 MP2K1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11604401 16093354 15485920 8621729 25155755 26496610 34407391 8394352 20212043 9311917 17724343 8157000 18556463 1326789 17979178 32707033 9733801 10757792 7731720 23934108 21336309 31980649 27703006 19197339 24746704 10958680 19058874 7527398 34017080 15866172
MP2K2 MK01 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12788955 11134045 23519423 21675959 11823456
ARAF RASK â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 25852190 30194290 28205554 28628118 25416956 34079125
RAF1 RASK â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 16093354 20080631 9564038 23153539 10783161 9446616 30194290 27684187 28628118 16041367 8307946 26721396 20802526 25852190 34526658 10882715 15192046 19029954 31980649 10958680 28205554 34079125
MK01 MP2K1 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 21336309 12788955 11266467 23241949 11352917 12697810 8157000 12594221 11134045 11279118 17255949 24623782 21675959 27884160 19058874 11823456 10757792 11741894
KSR1 BRAF â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
KSR1 BRAF â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
KSR1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19541618 8601312 19933846 12932319 17613518 18332145 15710605
RAF1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
KSR1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 7477354 12932319 9665134 9094715 19766101 23331499 8601312 19595761 11478855 8332195 15520859 8503013 16093354 19541618 19933846 10205168 7760835 18775988 18789263 11134016 8180183 1990291
KSR2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12975377 23331499
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513