Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H1-2 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-2 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TBP H1-2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17978101 12842912
PARP1 H1-2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18250087
ATF7IP FLT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PARP1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16647857
BUB1B CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11285280 10679238
PBK CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 10779557 5212518
XRCC1 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15367657 5217189
ESR1 HEXIM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18757415 21423213
POLA2 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FGFR3 HAUS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMC2 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
SMC4 NCAPH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
SMC4 SMC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17268547 5219584
NDC80 SPC25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
AURKB NDC80 â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 20471944
ESR1 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 21182205 20348541
DPEP1 SMC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 SMC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26166704 31527615
NDC80 SPC24 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
FLT1 FLT4 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
SPC24 SPC25 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CEP19 VCP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
ZWINT SPC24 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 20360068 15824131 24981860 26496610 26186194 28514442
ZWINT SPC25 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 20360068 24981860 26496610 26186194 28514442
BUB1B ZWINT â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SPC25 ZWINT â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
NCAPD2 SMC2 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
SPC24 ZWINT â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
NCAPG SMC2 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
TBP ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11595744 31527615 16713569 9259327
NDC80 ZWINT â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
NCAPG SMC4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
NCAPD2 SMC4 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
AURKB ZWINT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21775627
AURKB SKA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22371557
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
POLA2 POLE3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 10882098 10757793 12045100
SPC24 SPC25 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
NDC80 SPC24 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
SMC2 SMC4 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
NCAPD2 NCAPG â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
SPC25 NDC80 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14699129 14681455 20360068 28514442 15961401 33961781 24981860 22939629 26186194 25416956 34079125
NCAPD2 NCAPG â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NCAPD2 SMC4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCAPD2 NCAPH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NDC80 SPC25 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
NCAPD2 SMC2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPH SMC4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPG SMC2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPG SMC4 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPG NCAPH â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
NCAPH SMC2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SMC2 SMC4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
AURKB NDC80 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23569217 20471944 14602875
CDK1 BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20016069 23637705 29971233 23345399 23079597 26259146 17785528 20633640 19015317 33207204
CDK1 DDX3X â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16280325 17379183
CDK1 KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26615533 19007248 16565220 19691289 19001501 28487562 19664994 20068231 16455663 25660025 19690332 8548803 21522128 19413330 9235942 20068230
CDK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7592773 30392930 18691976 19387552 20068231 96029687 16371510 1400350 19941816
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
CSNK2A1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18971944 20507565 19118383 21576760 18583988 15066279 20471329 18452278 21592330 15367657 21118972 20533398
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
CSNK2A2 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18971944 28416484 20507565 19118383 21576760 18583988 15066279 20471329 18452278 25477519 21592330 15367657 21118972 20533398
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
POLE3 POLE3 â—¼   KO_DOWN_REGULATES ✅ - -2.96 2.95 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368