Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GPATCH8 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 NUMBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
MDM2 BHLHE40 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17347673 5219751
CDK5 NUMBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EGFR NUMBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
IGF1R YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RIPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10880512 5212735
NOTCH1 ITCH â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8313469 19567869
NUMBL ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16508312
MAGED1 RBFOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
NOTCH1 NOTCH4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330899 22363130
RBFOX1 NUMBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ITCH TRAF6 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
EPCAM LAD1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
1433G TAB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G GRIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F NUMBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F TAB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F GRIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KBTB7 NUMBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
K1107 NUMBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29262337 26496610
EAA3 FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EAA3 NUMBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UN5CL IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UN5CL NUMBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EGFR LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24797263 31980649
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
TRAF5 NUMBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 22593207
1433B GRIP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178
TULP3 KBTB7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
ESR1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23403292 31527615 19805454 21182205
RIPK1 TRAF5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29955050 11479302
BHLHE40 ROR2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
1433G NUMBL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 15324660
RIPK1 TAB2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ESR1 GRIP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17545996 9773983 17932106
TRAF6 NUMBL â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28974699 21988832 20079715 22593207
EGFR 1433B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
1433B NUMBL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
TRAF6 TRAF5 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8153045 21516116
TRAF5 TRAF6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27107012 32296183 29176576 21516116 25416956 22493164 33539883
IGF1R MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
1433G 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15324660 26344197 26496610 28514442 22863883 17979178
1433G IGF1R â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15324660 27684187 17353931
MDM2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17545634 10766163 11178989 16713569 31012223
NUMBL TAB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21988832 18299187
1433B IGF1R â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14651979 9581554 15629149 17353931
NOTCH1 ASCL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9102301 9133387 11306509
ESR1 NOTCH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
PRKCI EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18270268
TAB2 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 23986494 17626013
IKBKG RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
TAB2 TRAF6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
1433G 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 15324660 24981860 26344197 24255178 17085597 28514442
1433F 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 26496610 24255178 28514442 17979178
CDK5 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12769842 16510591
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
RIPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11116146
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1382070 31980649 24658140 12560083 9230083 15212693 10377409 15647376
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
ESR1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12897156 17166846 12750288 8324731 22787161 21169420 19578757
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
MDM2 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 25241761 28092675 12821780 18632619 17303558 19165858 36042202 20195357
IGF1R YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12767520 10826997 12444011 21540285 17145710 17353931 19030972 16931767 15324660 12175651
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
TAB2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
RIPK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
RIPK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10880512 21383699 21458669 14653779 10980203 17702576 9927690 16603398 16547522 16965765 10755617
ITCH RIPK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 19131965 20068034 21107885 21383157
ITCH NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12682059 10940313 23331499 16713569
ROR2 MAGED1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 16713569 12754255
NUMBL NOTCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9169836
NUMBL TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21988832 20079715 28974699 22593207
RIPK1 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15327770 16603398
ROR2 TAB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 TAB2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
ROR2 TAB2 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 23070005
TRAF6 TAB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 15492226 19675569 15932500 18180283 16251197 10882101 18299187 11259596 1551980 24061540 21988832 19112497 22924441 11518704 11809792 15836773 14633987 14751757 25290089 12496252 12609980 12242293 24735611 14982987 15327770 17720800