Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PLG PLAT â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2318848 7199524
PLG PLAT â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 2496749 2962641
PLAT PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11928826 1447176
SERPINE1 PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11113116 16713569
ANXA2 PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10077593
PRKCE APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CALR APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HMGB1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP PLAU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 ATF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
ATF2 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22643046 17258390
ATF4 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18729081 20101207
HIF1A BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17558861 19211554
MAPK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
CREB1 IL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
DNMT1 PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21437359 24117907
DNMT1 RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21868513 14528273
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
F10 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25769543 35114109
SP1 F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12911579
SP3 F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12911579
SERPINA5 F2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12878585 18362344
F2 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10996659 8428004
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 21454812
TP53 HMGB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547598 9472015
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
JUN RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9377582
KLF5 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16102021 10865841
TP53 KRT8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8615594
TP53 KRT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
PRKCE MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11350735
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
PRKCE MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16810323 16461926
MMP1 MMP9 â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 7780967 1371271
THBS1 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11606713 10900205
SP1 PDGFC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15247255
SP1 PDGFD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189269 18258854
SERPINA5 PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 2551064 16189514
PLAU PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721771 16189514
RARA PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10361124
SP1 PRKCE â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24825907 18249093
TP53 PRNP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24339999 19064990
SP1 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19064990
TP53 SERPINE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SP1 TGM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10886517 21248772
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
SP3 SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12414801 11517158 10825178 16734381 9329821 23825960 12200149 15247906
TP53 UBE2A â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
RARA KLF5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16224062 18466769 21383775 16102021 12101409
APP CALR â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
APP PRNP â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
RARA RARB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 22022577
HIF1A JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
JUN SP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
JUN MAPK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MAPK1 TP53 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
UBA1 UBE2A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
SP1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25879517 16478997 17215518 16713569 33572115 10506225
RARA SP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10361124 19401466 16713569 18270252
SP1 RXRA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10361124 10393239 16713569 18270252
SERPINE1 PLG â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11021826 20027185 25502501
PLG PLAU â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 2521625 2935528 1829461
PLAU PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 3920216 2829380 4226004
THBS1 PLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 6438154 2522013
ANXA2 PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 12468550 11978811
SP1 ATF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2145272 12760745
ATF2 PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8647095 11179965
CREB1 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11450946 16205321 18830594
SP3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22334592 20435036
CREB1 RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath
SP1 F10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8567696
HIF1A MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20631454 19285046 19950212
HIF1A MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17335808 18588890 20102637
PLAU HRG â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 2521625 2935528 1829461
MAPK1 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
MAPK3 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
RARA MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15246741 10415749 1682056
RXRA PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19538480
RARB PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19538480
SERPINE1 PLAU â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11021826 20027185 25502501
SP1 SERPINE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8268720 21436258 8764573
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
THBS1 TGFB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22943793 8349738 21900405
F2 SERPINA5 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PLAT SERPINE1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
HMGB1 TP53 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RARB RXRA â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
F2 FGA â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PLAU SERPINE1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
TP53 SERPINE2 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
BCL2L1 TP53 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
PLAU PLG â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 18633355 20027185 22470492 27216177
JUN APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8063812 11677255 8015372
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
ATF2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9990041 10915780 11850817 11410592 11739785 15691880 16405968 10464245 10500157 15314161 10066798
ATF2 TGFB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8119953 1400310 26225425
ATF2 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21479385 8335091 10471826 8703044 9151819
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
MAPK1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10777545 17081983 21098032 9430721 12110590 20068231 19690332 15304344 19413330 10878576 15192015 7737129 18669648 19647037
MAPK3 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10777545 12110590 20068231 15304344 15192015 19647037
PRKCE ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24727247 22304920 24357804 25545367 26645581 25728676
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
ATF4 CREB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17669268 17434604 18441292 15240803 15888447 16121183
SP1 ATP2A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12818568 8621466 17597815 14613864
TP53 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22869582 9582400 9989972 11713584 18172861 23519249 12705879 9000137 11713302
TP53 BCL2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 24814347 12667443 16151013 26556313 14963330 16713569 20837658 24474649 21900206
BCL2L1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 24814347 12667443 16151013 26556313 14963330 16713569 20837658 24474649 21900206
BCL2L1 VDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12767928 17209561 16189514 10365962 10737788
CALR LRP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759 25351513
TP53 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 24189068 8702807 10669755 22270849 12808109 17942917 19086036 20731879 16061648 20554748 24460719 11798189 10082575 15205322 18769160 19800042
JUN CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16393119 21135252 8917510 17166846 19622016 11402335 20220142 22853846 17670745 10567390 17496887 19499154 9878062 21474819 17278098 15282324 15467760 15994313 14672732 15574422 22550166 10066798 17637753 20482821 15574764 11745411 11410592 18084253 20037604 12794082 10790372 16860316 24190040 17501623 17477349 19435822 10500157 11432833
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
HIF1A CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23455892 20360945 20179204 15991006
SP1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10497251 22911796 19850937 9236224 17617380 9407106 15870300 22415074 10850422 9584162 10908361 22734486 16267018 9637785 19755513 11410592 11024050 15922873 12794082 20435036 22334592
JUN CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18813803 19219074 16406505 16880536 16054035 19190345 17000779 17439715 8545107 16396903 11274345 20107231
CREB1 PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 7543410 8647095 11179965
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
CREB1 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18471910 20136501 17721610
CREB1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 2170405 22357921 8648265 15908479 1845987 8803927 2542772 15608673 1404598 1320003 12372774
CREB1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11313407 12370343 17548609 12626549 15993752 12432566 8670878 8814256 11238674
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
F2 FGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25241761 2133223 2742826 1587268
FGA PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 3088041 11170397
SP1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15908479 16341057 9671487 1845987 8803927 2542772 7565693 15608673 9566920 1404598 2170405 10421838
JUN FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24342046 21479385 11052809 9756884 23744703 10325245 11896591 10421838
THBS1 FN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19542224 11773026 18042364 18226512
HIF1A SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19828020 10590062 11877282 17570486 18381294 9427542 14708599 17721610 15968405 16778202 17197388 19132225 20216986 21132271 14567996 14978738 20136501 17384280 12393531 19490965 8672239 11313255 20351105
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
MAPK1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16954218 10551817 18519666 18687685 26784107
MAPK3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10551817 18519666 24099156
TP53 HMGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9472015 23063560 11748221 16713569 11106654
HMGB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9472015 23063560 11748221 16713569 11106654
JUN IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 20557936 12370343 10700231 12884855 8436291 9541574 8397339 1737937 9605137 8683110 21832163 9590239 7989759 9774418 16116194 8473495 8114694 10878360 10320367 9233628 7642615 17097050 7565732 8468462 8660843 7739550 8051409 1740667 19181930
SP1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10656874 12560487 9175624 9756940 8814256
SP1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20148354 8355696 8892460 1406636 19437621 9054614 17502875
JUN PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16515541 18982462 8647095 3135941 1963081 12960165 1331936 9851700 1903195
JUN SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11440364 12390531 19887897 19288028 15069077 22926518 10591684 11223948 12905745 14592829 16105028 17890327 21969564 8917435 8342330 19088796 20351105
JUN MMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 22437631 10913304 20463008 20225236 10206959 16707434 20648623 9178763 15027120 19708869 10914841 15090544 14550555 9923649 11156425 9334186 8798622 16317516 19028685 11259586 16380175 12871225 15467742 10995748 21640141 16569638
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
JUN MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 16798740 16554298 11774399 15949416 11429784 15777790 16014933 10935492 11326313 18809380 21474819 21963718 19455716 9136992 17572495 23176293 15708369
MAPK1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8072547 11313929 15378002 12531896 12853483 23720779 9662434 1496019 17570479 1922387 11278277 11739718 16023596 20086174 25557171 7737130 26755651 8224842 14676207 17920329 25201974 9022811 22327296 18650425 8137421 18443042 12881422 18572021 17001009 33767435 7744008 23616010 26745678 14617628 11432833 16819515 22606284 12040039
PLAT LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 25879083 10632583 1502153 11560943
PLAU LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11560943
MMP9 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11279011
SERPINE1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 1500157915001570 15001579 16713569
SERPINE2 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14596620
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10377179 17604322 12048211
MAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 14965474 9765199 15116093 21675959 23443559 10781582 25241761 10446957 10958792 11409876 11709713 21147777 10673501 11551930 15867353 11875057 12091386
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 10383391 12048211 10377179 15688020 18003614 27852823 17604322 11606411 20432439 16551633 12824162 15212693 17900311
SP1 MMP9 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
TP53 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17311279 15899818 17077165 18635530
SP1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8226872 24755270 18028425 9514098 9520415 23799155 20529870 21840940 7860222 17049831 21963718 18357389 9150367 11060311 19616522 11830485 9748266 20638438
SP1 PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10452548 21437359 2172788 18419748 9851700
SP3 PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10452548 21437359
RARA PLAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7556191 19538480 12935977
SERPINE1 PLAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 2110366 16713569 8607113 3090045
SP1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23978400 10361124 21567400 21076612
SERPINB2 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 2161846 2166055 8388810 16189514
SERPINA5 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9365930 2752144 16189514
SERPINE1 PLAU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22449964 2544876 2161846 21199867 3090045 9184208
POT1 TERF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
POT1 TERF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
RARA RARB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10929206 16613989 7969156 8388240 2164682 1316240 8001825 1650576 16832676 16782888 10629053 2153268 9108446 1318502 10629091 11839811 11497266 9184230 14528273
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
RARB RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20102612 12576329 23331499 7565739 1310351 23180781
SP1 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15178441 23235480 12105191 10880342 1634545 11423472 17890327 8342330 9525928 15039136 11251188
TP53 SERPINE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 23665346 23063463 7479001 11470783 20947822
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
TP53 THBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12609716 10719731 10101800 24195060 10029407 16406676 19826414 9833779 12719977 9017002 22028325 10224095 9849855 7521539
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368