Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EZR DNAAF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VPS11 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21148287
GIT1 ARHGEF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218539 16628223
ACTN4 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
APC SCRIB â—¼   COLOCALIZATION 2.0 0.8 intact 16611247 6549797
ARHGEF7 PAK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
C5AR2 SCRIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CADM1 SCRIB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15811952 22285893
CADM1 CRTAM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15811952 22285893
CD4 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
PRKACA CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 CDH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CDH1 SCRIB â—¼   COLOCALIZATION 2.0 0.8 intact 21701506 8203421
CDH1 PHLPP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21701506 8203421
CTNND2 CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14610055 9971746
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8383887 22234184
CTNNB1 PKP4 â—¼   COLOCALIZATION 2.0 0.8 intact 5215447 12047349
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
PRKACA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12840026
SCRIB FZD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21983142 16687519
FZD3 VANGL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21983142 16687519
PRKCA HDAC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8307255 21952047
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
HSPA8 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SCRIB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MCC MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1CC MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAPK1 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
RPS6KA1 MAPK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPK3 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
SCRIB MCC â—¼   COLOCALIZATION 2.0 0.8 intact 7210514 19555689
SCRIB PHLPP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21701506 8203421
PRKCA RPS6KA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
RALBP1 PRKCA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217884 16087181
UBE3A SCRIB â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 11027293 5213066
TRIP6 SCRIB â—¼   COLOCALIZATION 2.0 0.8 intact 5217933 16137684
TSHR SCRIB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15775968
ARHGEF6 PAK1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
ACTN1 ACTN2 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
LATS1 YAP1 â—¼   PHOSPHORYLATION ✅ - 0.81 0.81 Signor 22658639
ZN263 VPS11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB ZO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
ESR2 PP1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 29509190
VCAM1 PP1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
IGF1R CTNB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22261717 27684187
SCRIB ARHG6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26617989
ZN263 SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZBT44 SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
LRC27 SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ARHGG SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30126976 32203420
RHOB CPNE8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
VCAM1 ACTN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CNPY3 LRIG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
RHOB EPHA7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
IL1R2 SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRIG1 SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SCRIB MCC â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 7210514 19555689
MCC SCRIB â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 7210514 19555689
MCC SCRIB â—¼   COLOCALIZATION ✅ 0.82 0.82 mint 7210514 19555689
RHOB PKP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
RHOB SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
VCAM1 SCRIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ACTN2 ACTN4 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
TRIP6 WTIP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PP1G SHOC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 27880917 26186194 24366813 28514442
PP1A SCRIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 27880917
PP1A SHOC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 27880917 31980649 26186194 28514442
CTNB1 MET â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11929826 11254878
CTNB1 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15572674 32603375 26657156 15060161 12408825 11050151 33190089 26123998 30836930 30986748 33742100 15806138
S6A12 SCRIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24550280 21525870
CL18A SCRIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ESR2 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21182203 25604459 29509190
CNPY3 SCRIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DTNA SNTB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 12206805 16713569 24981860
ESR2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18765668 11500849
ESR2 UBE3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33456993 25408199 17962381
RBM23 SCRIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MAPK3 RPS6KA2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ADRA1D UTRN â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ADRA1D DTNA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MED4 GIT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25281560
MED4 ARHG7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25281560
ACTN4 CTNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16204054 25241761
FGFR1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 18302981 11401320
HDAC6 CTNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18356165 23084749
CTNB1 SCRIB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24550280 34079125
CTNB1 PKP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12047349 33961781 27684187 34079125
VCAM1 TLN1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22623428 19738201
ADA1D DTNA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27382054 21115837 18468998 26617989
PHLPP1 SCRIB â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
ARHGEF6 GIT1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ADRA1D SNTA1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
YAP1 ZO2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24255178 34079125
ADA1D SNTA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16533813 15123239 26617989 18468998 27382054
WWTR1 LATS1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22078877 21555462 29787761 20412773 27847303 26116754
LRIG1 MET â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24828152 17178829
PP1G SCRIB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27880917 30344098 26617989 26186194 24366813 28514442
YAP1 PP1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25751139 25796446 24255178 27684187 24366813
SCRIB GCYA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30126976 24550280
ADA1D SCRIB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24550280 27382054 26617989
SCRIB PKP4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30126976 24550280
ARHGEF7 SCRIB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
DTNA SNTA1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
ARHG6 ARHG7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32203420 28514442 15306850 12499396
YAP1 CTNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24976009 23245941 27173435 27684187 33643786 21376238 29789528
CLK3 SCRIB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 23602568 32707033
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
TGS1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11912212 12754253
PAK1 SCRIB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 31980649
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SCRIB GIT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15975580 19041750 26617989
ADA1D SNTB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16533813 26617989 27382054 18468998 21115837
SCRIB MK12 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30126976 24550280
PHLP1 SCRIB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 21701506 33961781 24145035
LATS1 WWTR1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ACTN3 ACTN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16713569 10656685 9675099
SCRIB ILL22 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
CRTAM ILL22 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
PP1G PP1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 30344098 28330616 26496610 26186194 24366813 28514442
KS6A2 SCRIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29144123 30126976 31678930
SCRIB ZO2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15975580 34079125
SCRIB ARHG7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21132015 33961781 24550280 15182672 19555689 26617989 15975580 19041750
CRCM SCRIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29144123 30126976 19555689 33961781
PAK1 ARHGEF6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SCRIB ARHGEF7 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 15975580 5217786
SCRIB ARHGEF7 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 24550280
CRTAM SCRIB â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 15811952 22285893 26694968
CRTAM IFNG â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
CRTAM IL22 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
CRTAM TLN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
ESR2 VANGL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
SCRIB IFNG â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
SCRIB IL22 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
PRKACA KCNJ4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11749379 8893032 19635485
YAP1 LATS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27325643 29891922 28416659 27847303 32292505 17889669 30472188 33141042 18413746 22641346 26933062 18640976 24255178 27684187 22863277 24107629 30266805 31619268 21041411 21383157 30461308 24366813 20841485 28754671 25751139 25796446 27886176 25283809 18158288 34079125
MAPK3 MAP3K3 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
MAP3K3 MAPK1 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
MAPK3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14993270
PHLPP1 PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18162466
SCRIB TLN1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15811952 22285893 26694968
MAPK1 RPS6KA2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ARHGEF7 GIT1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CADM1 CRTAM â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CTNNB1 EP300 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PAK1 ARHGEF7 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218539 16628223
ACTN1 ACTN4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PAK1 GIT1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 25852190 16628223 31980649 23455922
GIT1 ARHG6 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32203420 10896954 21900206 28514442 10428811
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CD4 LCK â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
PAK1 ARHG6 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 23455922 9659915 31980649 32203420 15688026 21900206 28514442
LATS1 YAP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MAPK1 RPS6KA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ARHGEF7 PAK1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
APC CTNB1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 11251183 29045831 21664290 15327768 26496610 22682247 12628243 11972058 11533658 16510874 8259519 9707618 27902311 27684187 17318191 15327769 10773885 22056988 9482734 33858476 32533114 17510365 16212417 9286858 15525529 12000790 15355978 10545404 11707392 23840886 25241761 8638126 11712088 11166179 19576224 7890674 34079125
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDH1 CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
GIT1 ARHG7 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 16787945 25742295 32203420 17467235 10896954 15082779 16628223 12473661 28514442 21295525 10428811
ARHGEF6 GIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10428811 10896954 10592173 16373173 21900206
ARHGEF7 GIT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10428811 21295525 12473661 10896954 16628223 16787945 10592173 12695502
ARHG7 PAK1 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 23455922 16101281 31980649 32814053 32203420 20936779 16628223 16492808 26264872 10330411 28514442 11157752 29997244 16407834
PRKACA APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11050185 11166179 15649893 11689703
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
ARHGEF6 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23455922 11157752 9659915 10592173 15688026 21900206
PAK1 ARHGEF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 20936779 16101281 11096073 10330411 11157752 16628223 9726964 16492808 9659915 10592173 16407834 17392278 29997244 32814053 25472536 23455922
PRKACA ATP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 19651622 2548572 17081983 20068231 9824678 18669648
PRKCA ATP2B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9824678 11779484 1827443
LCK CD4 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 CRTAM â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 SCRIB â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16888650 8104794 11854499 8246987 3262426 12601806 17653867 23109003 12007789 16189514 17005671 15489916 15047060
CDH1 IFNG â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
MET CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17496910 17336101 22558232 16909210 12040186 19568798 14585353
CDH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 91.0 1.0 Omnipath 17145710 7542250 11348595 9512503 10652321 19016843 16909210 9233779 17220478 16219695 27177845 25344754 11245482 22752307 16983094 16212417 16574648 18593713 9535896 9819408 12830000 10772923 11801604 23180380 8227214 16546130 10085258 22056988 9700170 12640114 24424122 10381631 17087658 24798214 11226248 12875984 9405455 11712088 12061792 17909039 22158051 11960376 14706341 11254878 15023525 12169098 21255999 16125672 22850631 16126725 11113628 25468996 9326449 17524503 17057644 7876318 11401320 22715382 7954478 18593907 21152425 22375065
LCK CRTAM â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
MET CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17496910 25163657 24511551 22558232 11929826 16909210 24342833 12040186 26654598 19568798 14585353 23083465
EP300 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11050151 18987336 15806138 15060161 17410209
PAK1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 28007610 28423670 23543898 25639486 26547035 22369945 23162742 25472536 21822311 25225063 27713506 27910850
PRKACA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 33914026 16199882 22173096 21303971 33815677 22094462 17287208 26068882 26884171 33605402 21506126 24117889 12297048 21822311 16476742
IGF1R CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17496910 22558232 12040186 19568798 14585353
IFNG EP300 â—¼   ENZYMATIC_REACTION ✅ 31.0 1.0 ACSN 10485906 11489965 11579131 11777960 11870632 11964313 12413632 12818165 14607900 15634932 15778339 15811952 15814715 16286920 16424049 16713974 17016554 17559085 1825141 18272812 19833085 20038811 20819927 21149606 21411734 24658051 26755705 2965306 6425450 9834059 9864217
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
PRKCA EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 14504278 15531580 10970850 11387207 21899702 15843435 9516463 15647376
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
MAPK3 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27342992 23405013 18411303
FGFR4 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
FGFR4 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
PRKCA GRIN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12147342 11306676 8940188
MAPK3 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24089523
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
PRKACA KCNJ12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11181181
PRKACA KCNJ12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11181181
LATS1 WWTR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23026745 22078877 20412773 22658639 33086783 24550007 21808241 29787761 34022224 20594350
LATS1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 22863277 24366813 35044719 20048001 18413746 17889669 15302935 21383157 23752589 17974916 18640976 22641346 23027127 20841485 18369314 29179447 18669648 24255178 18565851 21909427 21170084 25283809 29487715 18158288 29496737 18220336 22658639 35210364 27325643 19141641 21041411 25180175 27322327 27847303
LCK SCRIB â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
MAPK1 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 8506364 7499846 8618896 15967991 8226850 8626561
MAPK3 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 8506364 8618896 8226850 7597029
PRKCA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8939914 12832467 9915826 17906627 32296183 19282669
MAPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17081983 32814053 20385094 11532940 7601337 23331499 15342917 8939914 21071413 23047924 20068231 11335727 9687510 12618428 18988627 18669648 23519423 23109003 18691976 12594221 9915826 17906627 8202512 9430688 19651622 12832467 11500364 14966081 29997244 25730857 8387505 10411321 18212344
MAPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19604315 15542607 16964243 15212693 11604394
MAPK12 SNTA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17081983 18669648 20068231 19413330 10212242
PRKCA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11704645 12598525 19074803 8903320 9160888
MAPK3 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 15342917 18039929 12832467 23109003 8387505 14966081 9915826 21071413 17906627 9430688 11335727 18988627 11532940 10411321
MAPK3 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 23602568 8939914 12832467 17906627
PRKCA MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 17496910 11940581 21386996 15075332 11447289 19615955 8294430 16488589 6321473 8321321 12845332 11313945 17570479 94124523 12040186 19568798 15567848 14585353
PAK1 NET1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18509476 15684429
PRKACA UBE3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 26255772 28559284 28835500
PRKCA RALBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16087181 17706599 21411502
SCRIB VANGL2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 21983142 12724779 23140627 16687519
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338