Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PLCB3 EZR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213905 11285285
PLCB2 PLCB3 â—¼   PHOSPHOLIPASE ✅ 2.0 0.8 Reactome 11015615 2841328
CFTR PDZK1 â—¼   COLOCALIZATION 2.0 0.8 intact 5213120 11051556
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CTNNA1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23949920 23431053
CTNNB1 WWTR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8383887 22234184
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
CTNNB1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16219695
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC PDGFRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15226411 18697203
MYC PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19602047 11509615
PTEN PDGFRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16456542 5218301
PDGFRB PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 8702949
PDPK1 PRKCA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PTEN PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11943559 23331499
SIAH1 SLC9A3R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12421809 5215881
YAP1 SLC9A3R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217948 16166090
SRY SLC9A3R2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9054412 5221357
WWTR1 SLC9A3R2 â—¼   COLOCALIZATION 2.0 0.8 intact 5213315 11118213
SLC9A3R2 SRY â—¼   COLOCALIZATION 2.0 0.8 intact 5217948 16166090
YAP1 TP63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213829 11278685
TRAF4 WWP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PDGFRB PTEN â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
MYC ANXA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 30081903
ESR1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23403292 31527615 19805454 21182205
CTNNB1 SIAH1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
CFTR SLC9A3R2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ACTN4 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21078666
CFTR PDZK1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
RDX SLC9A3R2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
YAP1 CTNNB1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 22234184 8383887
PTEN WWP2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CTNNB1 YAP1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SLC9A3R2 PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10748023
YAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23607968 22234184 23245941
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9259327 10409727 23874500 11014206 15604093 12554772 16282588 9427757 11113179 18451880 9121466 10598586 16713569 11165056 14715875 11376110 9774463 10760302 20608937 9192892 11003650 26487511 11867769 10454579 12574227 17363140 9773983 10731636 11358671 11250900 11682626 23975195 17627277 16606617 12630920 12714702 9192902 12738788 16957778 15140878
LPAR2 TRIP6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16624523 19293149 14688263 16713569 16189514
MYC NRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SLC9A3R2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PDGFRB PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
TP63 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278685 35044719
PDPK1 SGK1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
PDGFRB PIK3R1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
SLC9A3R2 CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 12369822 5215811
PIK3R1 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7536927 6730373
ACTN1 ACTN4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PRKCA PLCB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11278298 9660757 15302935 10893237
PRKCA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 92316961 15212693 26888287 1377674
CTNNB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21533051 19778454 16510874 12095419 17360646 18852287 15576399 19561604 20300972 19662654 15579438 17724465 9727977 24447505 18679417 12907606
SIAH1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 28481365 11389840 32671611
PRKD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26895471 19141652 29108267
CTNNB1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10477752 25241761 16219695 11716761
CTNNB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19751508 7542250 11967263 22290435 19623618 16574648 23343194 11955436 22270359 22761862 16039586 15810077 17143292 12051714 8666229 22943793 15576399 21151179 16940750 17306568 17666529 21285352 19619488
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
RPS6KA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10949034 15528270 19925796 15461668 25336146 11139588 12118371 30034315 15059947 16076840 7491495 12093745 11432835 10411321 11507039 9528769 7838153
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
ESR1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11029009 11689445 16169518 23065768 16713569
PRKCA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 14504278 15531580 10970850 11387207 21899702 15843435 9516463 15647376
SGK1 KCNJ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8621594 12878206 12684516 17570479 29352074
PDPK1 KRAS â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
KRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
PRKCA KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20802526 34333552 23331499 25713064 27791178 18458061 9922370 18182391 16483930
LPAR2 TRIP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15988003 14688263 19293149 16713569 16624523
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
PDPK1 NRAS â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
NRAS PIK3R1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
NRAS PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8052307 7820549 9150145 8665852 21779497
PDGFRB PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 10752619 8564419 1372092 7486683 7692233 7536927 16713569 11710529 8382612 8086421 11896612 8670861 8388538 9153411 1330535 17496910 1314164 16135792 7680644 19864249 10697503 15377662
PDPK1 SGK1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11500365 11687500 11747822 12670391 15802604 16286006 17680028 18802401 19109239 19122654 20932932
PDPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20058876 18767875 10480933 7642538 17906627 27028868 9430688
PDPK1 PRKCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15209375 11078882 10698939 9889098
PDPK1 SGK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 16286006 25384981 18802401 12387817 17916563 23331499 11807089 16189514 12023960 10191262 22042038 10357815 24760523 11500365 23317821 20932932 12912918 15209375 24864229 17680028
PTEN PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PTEN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PRKCA PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15212693 18337243 11741879 11948398 17570479 34010649 10197446 10867018 15024053 15383279
YAP1 WWTR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 12807903 18280240 18617895 21666501 23708000 25502501 26711338 7782338