Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TRAF2 PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GRN PRKAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ADAMTSL4 OTX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
OTX1 TNS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
OTX1 SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
OTX1 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 CHRD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
NUFIP2 CHRD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRB2 CHRD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FXR1 CHRD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ADAMTSL4 PLSCR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ADAMTSL4 SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ADAMTSL4 CTSB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16364318 5218155
FXR1 ADAMTSL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ADAMTSL4 CTSB â—¼   COLOCALIZATION 2.0 0.8 intact 16364318 5218155
KRTAP4-12 ADAMTSL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CATSPER1 ADAMTSL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ADAMTSL4 STK16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP4-12 AQP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MDFI AQP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SPRY2 BRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11698404 19690147
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
UBASH3B CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15159412
SPRY1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16893902 19915061
SRC CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17094785 7033811
NCK2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GRB2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CBLB â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SPRY2 CBLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11053437
CRMP1 FXR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SP1 CRMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18524846
ETS1 CTSB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10701774
FXR2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRAP2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
FXR1 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRB2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15834155 5217666
ITSN1 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15834155 5217666
DNM2 GRAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR PTPN1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 9355745 6671413
SH3KBP1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11894095
UBE2D2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
EGLN1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 0.8 0.8 mint 7987706 20840591
HIF1A EGLN1 â—¼   HYDROXYLATION ✅ 0.8 0.8 mint 5217229 15474027
EGLN1 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
HIF1A EGLN2 â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
EGLN3 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
KRTAP4-12 EIF4E2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SP1 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12706891 8247540
ETS1 SPRY2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14644509
HOXA1 FBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FRS2 PTPN11 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
FXR1 SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 SPRY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 MAPKBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 SPRY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 NCK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 MAPKBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SP1 FXR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16886907
GPRIN2 PLSCR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GPRIN2 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP4-12 GPRIN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SPRY2 GPRIN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP4-11 GRAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
KRTAP4-12 GRAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GRAP2 KRTAP4-11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SPRY1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6169676 16893902
PPP2CB GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
SNX3 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPP2R1A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 TFAP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
KIF1A GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LCE1B GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HOXA1 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SPRY4 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
HIF1A KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
PLSCR1 HOXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP4-12 HOXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MDFI HOXA1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 21653829 3002166
HOXA1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RASA1 HRAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221569 9219684
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
PTPN11 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
KDM1A SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A NR1H2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
ZNF417 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP4-12 SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP4-12 PLSCR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KRTAP4-12 ZBTB16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PLSCR1 LASP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LASP1 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MEOX2 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
NR1H2 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZNF417 MDFI â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SP1 MEOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7623821
MKNK1 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20927323 8288108
SPRY2 MKNK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16479008 19690147
PPP2CA MKNK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16479008 19690147
PPP2CB MKNK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16479008 19690147
PPP2R1A MKNK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16479008 19690147
PPP2CA MKNK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20927323
NCK2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17310244 11557983
NUFIP2 SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ZBTB16 PLSCR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SPRY2 PLSCR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SPRY2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16479008 19690147
PPP2CA PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PPP2CA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24382322
SPRY2 PPP2CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16479008 19690147
PPP2CB PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
SPRY2 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16479008 19690147
PPP2R1A PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PTPN1 SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6732073 9600099
SPRY2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
SNX3 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
UBASH3A SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
TRIM51 SPRY2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SPRY2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TFAP2A SPRY2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14644509
STK16 VHL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 17353931
TRAF2 ZBTB16 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HEXIM2 HOXA1 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
VPS25 VPS36 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
BAG3 SPRY2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
CATSPER1 KRTAP5-6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
LCE4A SPRY1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
HOXA1 LCE3C â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
HOXA1 LCE1C â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
LCE1C OTX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LCE1C SPRY2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
FRS3 STK16 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
KRTAP4-12 SPRY1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LCE3C SPRY1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
LCE1B LCE2D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
LCE1B LCE3C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
PRKAB2 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
NCK2 CBL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24287595
KRTAP4-12 LCE1C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
KRTAP9-2 SPRY1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
LCE2D SPRY1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
LCE1C SPRY1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
LCE1C LCE2D â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
RASA1 GRB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12441060 16189514 16713569
HOXA1 SPRY1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
VHL EGLN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22286099 17986458 26215701
ETS1 SRC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15788656 25117710
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
KRTAP4-11 LCE1C â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
SIAH2 TRAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12411493 16713569
KRTAP10-8 LCE1C â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
KRTAP5-6 LCE4A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
GRAP2 CBL â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25814554 12496419
SPRY2 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 16893902 6169676
EGLN3 SIAH2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16958618 25202994 15210114
KRTAP4-11 LCE3E â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
KRTAP5-9 LCE1C â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
SIAH2 UBE2D2 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
HRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 34591642
HRAS BRAF â—¼   PROXIMITY ✅ 0.87 0.87 mint 30194290
CBLB NCK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26871637 26186194 21516116 16713569 25416956 16189514
NEDD4 EGFR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
CATSPER1 KRTAP4-11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CATSPER1 KRTAP10-11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
EGFR SH3KBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
FRS3 GPRIN2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
KRTAP4-11 LCE3C â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
MEOX2 USP20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
EGFR UBASH3B â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
ETS1 FOXO1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HOXA1 SPRY2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PTPN1 SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
KRTAP5-6 LCE1C â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PLS1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12871937 16713569 12009895
HIF1A EGLN3 â—¼   HYDROXYLATION ✅ 0.88 0.88 mint 5217229 15474027
GPRIN2 KRTAP10-5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
LCE1B LCE1C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
LCE1C LCE4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
SRC RASA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11389730 16189514 16713569 1717825
FXR1 FXR2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
KRTAP4-11 LCE4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
KRTAP5-6 LCE3E â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CBL ITSN1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR NCK2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
GPRIN2 OTX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CATSPER1 KRTAP10-5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MB21D2 SPRY2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
FRS2 GRB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GPRIN2 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
FRS2 CBL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17944804 20038681 11997436
PTPRB EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8870675 19167335 28065597 31980649
LCE1B LCE4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KRTAP10-11 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
BAG3 MDFI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FRS3 HOXA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
DNM2 ITSN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
EGFR PTPN1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
EGFR RASA1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
FGF1 S100A13 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MDFI USP20 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FRS2 PTPN11 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
FRS3 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
RTF2 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SRC CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22203672 29899407 17141222 18996392 12941616 15135048 18273061 10829062 31120930 19861161 7782294 16713569 8635998 11994282 17094785 16636290
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
SPRY4 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18273061
CREB1 SPRY2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17599098 14644509
CRIP2 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SRC CRMP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CRMP1 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSTB SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SPRY2 CTSB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ZBTB16 DNM2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNM2 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PTPN1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 6671413 9355745
NCK2 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 22973453 9843575 16713569 25402006 1333047 10026169 9737977
PTPN1 EGFR â—¼   PHOSPHORYLATION ✅ 0.9 0.9 mint 6671413 9355745
PTPN1 EGFR â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 6732094 9050838
EGFR PTPN1 â—¼   COLOCALIZATION ✅ 0.9 0.9 mint 25796184
HIF1A EGLN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26611735 23413029 16511565 16155211 20812988 22946054 27563096 33550096 18264140 16407130 20840591 24681946 31763849 15474027 17069766 20724477 34007068 25974097 29279301 15721254 17442832 25361009 17353276 19604478 18063574
HIF1A EGLN3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 18264140 26972000 23345396 18063574 16511565 16155211 15721254 30067985 18402654 31239290 15474027 25416956 17353276 17069766
TFAP2A ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1945412 8247540
FAM219A SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FBN1 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FRS2 PTPN11 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 11447289 17673906 25772309
FXR2 FXR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21653829 24981860 7489725 29395067 8668200 24778252 28514442
RASA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12441060 16713569
KRTAP10-5 LCE3C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
NR1H2 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NUBP1 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RAF1 PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 502464200 8203796 16239230
SRC PPP2CA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
RAF1 PPP2CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 502464200 8203796 16239230
PPP2CA TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17188031
SRC PPP2CB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
PPP2R1A PPP2CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936019 16039140
PPP2CB TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17188031
PPP2CB PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11959144
SRC PPP2R1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
PTPN1 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17570831 15133032 11350745
PTPN11 SPRY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16481357 15031289
SRC RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7517401 8876196 17097642 16189514 10205168
SPRY4 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12717443
SDHB SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SP1 SPRY2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17599098 14644509
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
ZBTB16 SPRY2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SPRY2 UBR1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SPRY2 SRC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
CATSPER1 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CATSPER1 MDFI â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
DNM2 GRB2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
KRTAP10-5 LCE3E â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
EGLN2 HIF1A â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
KRTAP4-12 OTX1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CBLB SH3KBP1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
GRB2 SPRY2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KRTAP4-12 LCE2D â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP4-12 KRTAP5-6 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
KRTAP10-11 OTX1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP10-5 OTX1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP4-11 OTX1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP10-11 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
KRTAP10-11 LCE1B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CATSPER1 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HOXA1 LCE4A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CATSPER1 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
PPP2R1A PPP2CB â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217765 15936019
NEDD4 UBE2D2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
EGLN3 HIF1A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
KRTAP10-8 SPRY1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CATSPER1 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
HEXIM2 MEOX2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP10-11 MEOX2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP5-6 OTX1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP4-11 LCE1B â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CBL SH3KBP1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
KRTAP10-5 LCE1C â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP4-11 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP9-2 LCE3E â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
HOXA1 LCE2D â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP4-12 LCE3C â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
HOXA1 KRTAP10-5 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP4-12 LCE3E â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP4-12 LCE1B â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
MDFI SPRY1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
KRTAP10-8 STK16 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
LCE4A MDFI â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP5-9 OTX1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-11 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-12 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
KRTAP5-6 LCE1B â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
HOXA1 KRTAP10-11 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-5 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP5-9 SPRY1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
MEOX2 SPRY1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-8 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-12 MEOX2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP5-6 MEOX2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP5-9 MEOX2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
MDFI OTX1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
BRAF RAF1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
EGLN1 HIF1A â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
KRTAP4-12 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP5-6 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
HOXA1 MDFI â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP4-11 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP10-5 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
LCE3E MDFI â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
KRTAP9-2 LCE4A â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
SH3KBP1 CBLB â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6170278 12177062
SRC PTPN1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 6672195 16115959
SRC PTPN1 â—¼   PHOSPHORYLATION ✅ 0.94 0.94 mint 6732073 9600099
SRC PTPN1 â—¼   DEPHOSPHORYLATION ✅ 0.94 0.94 mint 11007774 6671922
PTPN1 SRC â—¼   DEPHOSPHORYLATION ✅ 0.94 0.94 mint 6764906 16537444
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HOXA1 KRTAP5-6 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
HOXA1 LCE1B â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
HOXA1 KRTAP4-11 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
HOXA1 KRTAP4-12 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-5 LCE1B â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
LCE3C MDFI â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-5 MEOX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-8 MEOX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-8 LCE3C â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP4-11 MEOX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP9-2 MEOX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-8 OTX1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP10-8 KRTAP4-11 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP5-9 LCE1B â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP9-2 OTX1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP5-9 LCE4A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP5-9 LCE2D â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP5-9 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
CBLB UBE2D2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
HOXA1 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
HOXA1 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
KRTAP4-12 LCE4A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
GRN HOXA1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 21653829 3002166
KRTAP10-8 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP5-9 LCE3C â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP5-9 LCE3E â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
HOXA1 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP10-8 KRTAP5-6 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP10-8 LCE4A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP10-8 LCE3E â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP10-8 KRTAP9-2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP10-8 LCE2D â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP10-8 LCE1B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
KRTAP9-2 LCE1B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
CBLC SRC â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BRAF HRAS â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CBLB EGFR â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
KRTAP5-6 KRTAP5-9 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
CBLB GRB2 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
RAF1 BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8396417 22510884
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
SH3KBP1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6170483 15090612
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
HRAS RASA1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CBL UBE2D2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
RAF1 HRAS â—¼   PROXIMITY ✅ 0.98 0.98 mint 18273062 6540139
HRAS RAF1 â—¼   PROXIMITY ✅ 0.98 0.98 mint 18273062 6540139
CBLC EGFR â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CBL SPRY2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
VPS25 VPS36 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CB PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
HRAS RAF1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SPRY4 TESK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17145710 12027893 17974561 15584898
HIF1A AQP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21612401 9537326
PRKCD BAG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23108398 25925243 28680391
GRB2 BRAF â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
GRB2 BRAF â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
HRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 7706312 14970219 18567582 12932319 8073291 1386920 23331499 8601312 9154803 18988627 8668348 21779497 19541618 19933846 17563371 18098337 16803888 26165597 24441586 16135787 12917261 15710605 10545207
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
SH3KBP1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 20130058 20711168 12618476 11894095 16407834 16713569 11071869 19268472 25472714 17306257 22262777 15456872 11152963 10679202 15962011 25036637 15107835 22833562 11067845 11894096 12177062 17675467 21830225 12135478 24167568 16228008 12874286 17072306 15090612 14596919
FRS2 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20038681 11997436
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
SPRY2 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 21596750 15004239 16479008 18273061 11053437 16893902 15962011 12593796 17974561 12234920 12593795 17255109 20461437 12815057 11983899 20877636 20124286 20622121 16246327
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBLB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17145710 19531499 11375397 10086340 12577067 10542134 17635922 10514377
CBLB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10022120 25416956 21706016 31467278 32814053 9614102 17635922 11375397 8626404 16189514 21900206 20936779 27107012 12577067 10514377 19531499 10086340 29997244
SRC CBLC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9988270 20525694 24425877 14661060 22888118
CBLC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10362357 22888118 17635922 10514377
CREB1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17526027 19155497 19750005
DYRK1A FOXO1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11980723 12138125 16511445 19685005
DYRK1A SPRY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 27308401 18678649 20804972
DYRK1A FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 19685005 16511445 26153519 22159921 12964950 11980723 24676346 28521392 11311120 12507516 19188143
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
TFAP2A EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16449191 8621697 14522076
PPP2CA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PRKCD EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 11447289 8321321 11313945 12040186 15302935 6321473 1860884 6090944 19568798 14585353 17496910 21386996 2984676 11940581 85012702 19615955 2987962 12845332 3379075 15567848 16488589 17956904
PRKD1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17081983 3138233 18220336 19369195 18691976 2987962 10523301 2984676 19413330 16083266 17192257 26465157 18669648 15302935
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 8647858 16273093 7991458 1850098 17570479 1633149 1385407
EGFR NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1333047 23331499 10026169 9737977 24658140 16713569 25402006 9843575 1333046
EGFR PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 25796184 31980649 8621392 12573287 18253097 11106648 11506178 24658140 7540771 9050838 9355745 15982634 25402006 10889023 7693694 8999839
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
UBE2D2 EGLN1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
HIF1A EGLN1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23487784 12839937 22075993 20574527 15563275 19628018 18072750 24558194 22451659 16157596
HIF1A EGLN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
EGLN1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19604478 20840591 16511565 23413029 12351678 15474027 22946054 15652751 16407130 25361009 31763849 32755251 16391536 15721254 20724477 24145445 17353276 18264140 26611735
HIF1A EGLN2 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 11.0 1.0 Reactome 11292861 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907
EGLN2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15652751 16391536 15721254 16511565 24990963 11292862 12351678 24145445 17353276 11292861 15474027
UBE2D2 EGLN3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
HIF1A EGLN3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19828020 15156561 20727020 15823097 22555025
HIF1A EGLN3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
EGLN3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17145710 15652751 26972000 15721254 16391536 16511565 24990963 12351678 31515488 24145445 17353276 15474027
FGF1 ETS1 â—¼   UP_REGULATES ✅ + 6.0 1.0 ACSN 14517404 16272825 16682805 21081489 26183471 9242465
ETS1 GP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15466856 11504709 10194443
HIF1A ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17615296 9157999 9278421 11708773 16716598 12080085 10403805 16887934 15181457 7539918 12490555 1823643 12829734 13130303 15451019 9746763 8943284 15111329 9159130 11566883 21041997
GRB2 FRS2 â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11777939 11997436 12040186 12175651 12640133 14585353 15173823 15567848 15574420 15863030 16102570 16488589 16582911 16887996 17496910 17673906 19449109 19568798 24027568 25772309 26552706 6321473 7510700 8551221
HRAS FRS2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 FRS2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11777939 11997436 12040186 12175651 12640133 14585353 15173823 15567848 15574420 15863030 16102570 16488589 16582911 16887996 17496910 17673906 19449109 19568798 24027568 25772309 26552706 6321473 7510700 8551221
SPRY2 FRS2 â—¼   DOWN_REGULATES ✅ - 4.0 1.0 ACSN 11447289 11997436 15173823 17496910
SPRY1 FRS2 â—¼   DOWN_REGULATES ✅ - 4.0 1.0 ACSN 11447289 11997436 15173823 17496910
GRB2 FRS2 â—¼   DOWN_REGULATES ✅ - 30.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11777939 11997436 12040186 12175651 12640133 14585353 15173823 15567848 15574420 15863030 16102570 16488589 16582911 16887996 17496910 17673906 19449109 19568798 24027568 25772309 26552706 6321473 7510700 8551221
FRS2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8780727 9182757 12974390 11997436 16189514 12402043
FRS2 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 23331499 10650943 9632781 11360177 11447289 29997244 12974390 16189514 25159185
FRS3 GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11353842 8780727 11447289 7559490 9182757
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 RAF1 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 RAF1 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
SPRY2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11447289 11997436 15173823 17496910
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
SPRY1 GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11447289 11997436 15173823 17496910
SPRY1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17496910 11447289 11997436 15031289 12402043 15173823 16893902
SPRY2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17496910 11447289 10940627 11997436 16189514 12402043 16339969 15173823 16893902
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
UBE2D2 HIF1A â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
RAF1 HRAS â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 HRAS â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 HRAS â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
SP1 HRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8106522 8208618 3012774 11559711 21931711 8027084 1776841
RASA1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10769036 11389730 23331499 18829532 7628625 9219684 10592173 8663024 16713569 26721396 8360177 8537347 1904555 10394594 2833817
SPRY2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17496910 11997436 15173823 11447289
SPRY1 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17496910 11997436 15173823 11447289
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
HRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 147.0 1.0 Omnipath 17145710 18273062 9523700 1639773 8601312 19595761 20133694 11032808 9154803 10882715 14654780 1996324 19222999 16301319 11948414 8530446 7969158 11313862 9150145 20080631 1990291 12750173 15031288 12932319 9665134 8805624 8340422 1386920 23331499 16916524 16041367 23180781 18988627 20178605 15688026 15664191 22169110 11733498 7862125 8180183 19063885 12391160 9144171 8035810 9020159 14724584 19696784 21779497 9261098 12173045 12620389 8628317 19914712 1708096 19933846 26721396 7730360 10205168 8332187 16803888 18775988 12917261 9099670 10545207 25684575 8670882 10783161 12379659 10887184 17569879 21071413 8332195 7523381 10531446 24929361 8503013 16093354 19541618 10369681 8911690 18073111 11136732 10922060 7760835 11134016
SRC LASP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 32872485 24913448 32075106 19718473 15138294 25622104
MKNK1 SPRY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16479008 19690147 19864419
PRKCD PLSCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10770950
SRC PLSCR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12871937 15212693 11390389
SP1 PPP2CA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19750005 19420015 12076969 21420382
SRC PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 25003662 10978272 21292165 23796501 24676687 22771321 24395787 17635907 26378614 16286244 27013170 23222956 25726524 24997451 31992581 12921784 1325671 17303700 23251465 20558158 21554241 23926298 25931585 22299660 18208556 21791414 23436320 32130916 17394530
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18039929 7604263 16680151 16239230 10995457 18042541 18588945
PPP2CA PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11959144
SRC PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 15851033 14970215 17569658 19366211 26876198 27203386 15961393 24211614 16982614 17570831 23329791 23329794 15541367 18550549 22689788 28637715 14715667 29422059 17658731 10319993 19138410 11927579 29452094 19632318 15337529
PRKCD PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15212693 11741879 11948398 23109817 21726532 10867018 15024053 15383279
SRC PRKD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12637538 28174535 28842658 17804414 12505989
PTPN1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 10698938 25585026 17092689 17974954 16537444 18332219 9600099 15866871 8647855 9261115 11346638 12857726 12468645 11007774 1646596 16115959
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
SRC RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7692235 12551923 7517401 17097642 15258589 9689060 16189514 16630891 10998357 11376654 29063113 8876196 10205168 28846113 12952943 22592532 11134016 15710605 16170185
SRC RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11389730 1717825 16713569
SPRY1 RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17496910 11997436 15173823 11447289
SPRY2 RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17496910 11997436 15173823 11447289
SRC SPRY2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18683950 15564375 12815057 15637081 16000370 15212693 12593795 18678649 16893902
VHL UBE2D2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499