Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SRP54 SRPRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30649417 12913112
RPL10 SRP68 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SRP72 SRP68 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30649417 8388879
SRPRA RUSC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EGFR NRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR KRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
ERBB3 FGFR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB3 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
ESR1 PRSS23 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22291950 18414489
IGF1R INSRR â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
EGFR TUBA1A â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CANX RPN1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
SRP19 SRP72 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
SRP54 SRP68 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL10 SRP14 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CANX RPN2 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
ESR1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
RUSC2 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
EGFR LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24780295 26320552
CANX DDOST â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
FLT1 FLT4 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
RPL10 SRP19 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
IGF1R INS â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
INSRR INSR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 8916919
RAD18 SRPRB â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
RPL10 SRP54 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
INSR INSRR â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
DDOST RPN1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
RPN1 RPN2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
RPL10 RPL10A â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
INS IGF1R â—¼   PHYSICAL_INTERACTION ✅ + 0.88 0.88 Signor 1851182
SRP68 SRP19 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 24700861
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
SRP19 SRP54 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30649418 12244299 16189514
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23436906 10527633 27756321 21278786 18803307 17148612 22439932 25315821 10572067 24189400 23866081
ESR1 RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21737465 21947652 22878616
SRP68 SRP72 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
DDOST RPN2 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
SRP14 SRP72 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
SRP14 SRP19 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
SRP54 SRP72 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
SRP14 SRP54 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
RAD18 SRPRA â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
INS INSR â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SRP19 SRP54 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SRP14 SRP68 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL10 RPL10A â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPN2 STT3B â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SRP19 SRP68 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPN1 STT3B â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SRP72 SRP68 â—¼   PHYSICAL_INTERACTION ✅ + 0.99 0.99 Signor 30649417
DDOST STT3B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SRP54 SRP68 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DDOST RPN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPN1 RPN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
DDOST RPN1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
SRP68 SRP72 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
NRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
KRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
HRAS ERBB3 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17170218 20021813 16087727 19250214 10982795 24281069 18414489 15595626
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
NRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
INS IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 1851182 18988627
INS INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8393875 21743783 21317886 24296476 26374090 29069585 26245346 16956584 19902173 20332342 23363978 23331499 18988627 23302862 22832498 2550426 15870194 11278498 19752148 29512653 23304064 24633815 17227660 22521887 23223021 30197476
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368