Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
NEK7 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BMI1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6948569 19233177
CDH1 EPCAM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESRRG ESRRA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17157980 15821111
MYC HERC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
UBC IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRIM29 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
USP2 UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
MYC MFAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC SETX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
SUMO3 UBA2 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
SUMO2 SETX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19471022 21252943 16524884 21693764
PARK2 PARK7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
TRAF6 USP7 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CDH1 EPCAM â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
SUMO2 SAE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19471022 25027693 32786267 26496610 16620772
SUMO1 SUMO3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 17938407 21098080 15576338
SAE1 SUMO3 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
NAE1 NEDD8 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
NAE1 UBA3 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
MFAP1 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
MYC MFAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
VCP DERL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 15215856
UBE2I PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11477070 15976810 18339323
SUMO1 PARK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11477070 15976810 18339323
SUMO1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18093978
SAE1 UBA2 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
VCP DERL1 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 15215856
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
NEDD8 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
UBC VCP â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
SUMO1 SAE1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 15660128 12941704 9920803 12924945 19246003 20164921
SAE1 SUMO2 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SUMO3 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
UBA3 NEDD8 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24654937 14690597 21145461 16503656 9694792 27182664 18652489 10207026 16620772
SAE1 UBE2I â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
DERL1 VCP â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
SUMO1 UBA2 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
SAE1 SUMO1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBC USP2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NAE1 UBA3 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SAE1 UBA2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBA2 UBE2I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GSK3A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11018017 17081983 2663470 11877389 14563837 8247524 16023596 15150404
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
MYC CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9632747 19176757 23364919 10523846
NEDD8 UBA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16620772 21145461 16503656 14690597 10207026
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368