Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
ELOC CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5219492 17183367
CRX PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19850845 18172122
POLR2B CTDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15670829
NFE2L2 CUL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21793854 20452971
UBB DAZAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
GTF2F1 GTF2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218897 16878124
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
NFE2L2 KEAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19560419 23850759
KEAP1 SKP1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NFE2L2 KEAP1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19560419 23850759
MED31 SUPT5H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RBX1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15572695 19560419
VCP NSFL1C â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
NSFL1C VCP â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PSMD2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
POLR2B SETD2 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
POLR2I SUPT6H â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RBX1 UBC â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RBX1 UBB â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
PLAA UBXN7 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
POLR2B RPAP1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
NPLOC4 UFD1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 20414249 7903886
AMFR UBB â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
CUL3 KLHL22 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
MED14 POLR2I â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
MED7 POLR2D â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
POLR2I POLR2M â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
UBXN7 CUL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
CUL1 DDB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22474075 21145461
UBXN7 CUL4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
CUL4A WDR26 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17041588 32235678
CUL4A SKP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22474075 21145461
RBX1 ELOC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33504946 12149480
UBXN7 ELOC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22537386 18775313
CUL3 TERA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 21145461
RN111 UBXN7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBXN7 KLH12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
UBXN7 KLDC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
UBXN7 UFD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
UBXN1 BIRC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25681446 18775313
DDB1 BRWD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 16964240
UBXN7 BRWD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
UBXN7 BRWD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
UBXN7 CUL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
CUL3 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 21145461
CUL4B UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 21145461
WDR26 DDB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29911972 17041588
TRAF6 DDB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25499913 17353931
UBXN7 HIF1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22537386 18775313
MED10 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 15175163
MED10 POLR2B â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
NUAK2 UBXN7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBXN7 RBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22537386 18775313
SOX2 UBR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30894683 23667531
SOX2 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26186194 23667531
UBXN7 WDR11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26389662 18775313
TCEB1 TCEB2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
POLR2B SUPT6H â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
MED21 POLR2I â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
UBB UBR5 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
NPLOC4 UFD1L â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
UBXN1 CUL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34237211 28152074 18775313
CUL4A BRWD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31973889 16964240 21145461
UBXN7 TOPRS â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26389662 18775313
KLDC3 ELOB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18187417 31253590 21145461
RBX1 ELOB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33504946 12048197 31253590 12149480
NEDD8 ELOB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31253590 21145461 16503656 18247557
KLDC2 ELOB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 18187417 31253590 33961781
NEDD8 ELOC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21145461 16503656 18247557
KLDC2 ELOC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 18187417 33961781
KCNKG NPL4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
UBXN7 KLDC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26389662 18775313
KLDC3 NEDD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 21145461
KCNKG UBXN7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
UBXN7 CUL4B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22466964 31973889 18775313
MED21 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
VPRBP NEDD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33355139 17609381 21145461
SKP1 UBB â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
MED6 POLR2B â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CUL3 KLHL13 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CUL1 UBB â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TCEB1 UBXN7 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
UBXN7 NPL4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26389662 18775313
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
BIRC2 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
NEDD8 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PLAA VCP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
POLR2D SUPT6H â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CUL1 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
PSMD2 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
VPRBP CUL4A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17609381 30166453 21145461 30590706 25532805 33355139 20870715 18606781 17630831 16949367 17079684 19295130 31973889
CUL4B BRWD3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31973889 26496610 31753913
MED7 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
MED6 MED14 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9734358 24981860 26344197
UBXN7 NEDD8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22466964 24076655 22537386
TRAF6 UBXN7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
CUL2 UBXN7 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MED6 POLR2D â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NEDD8 VHL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CLEC19A UBXN7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
MED7 POLR2I â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
UBC UBQLN2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
MED21 POLR2D â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
UBXN1 CUL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21145461 18775313
ELOC CUL3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21988832 21145461
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
TRAF6 PSMD2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
SOX2 WDR26 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23667531 28794006
GTF2F1 GTF2F2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MED31 POLR2D â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
MED10 POLR2D â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
NEDD8 TCEB1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CUL4A CUL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17079684 32235678 21145461
HIF1A CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23401859 27320910 18323857 17439941 17132228 19940151
TERA CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22466964 21145461 18775313
KLDC3 CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 18187417 26186194 28514442
KLDC2 CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 18187417 33961781 21145461
KLDC3 ELOC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 18187417 21145461
MED7 MED31 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 20211142 24981860 26186194 28514442
VHL NEDD8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11024059 17353931 18323857 16503656 15060148
SKP1 UBC â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBXN7 VCP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
KEAP1 RBX1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED31 POLR2B â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
MED31 POLR2I â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
UBXN7 CUL2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21145461 22466964 22537386 26389662 18775313
ERCC8 CUL4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12732143 29225035 21145461 26826127 29531219 16751180 16949367 31973889 22902626
CUL4A ERCC8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TRAF6 TERA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14743216 17353931
ERCC8 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 21145461 29531219 26496610 16949367 31973889 22902626
VPRBP CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21145461 22038470 26496610 33355139 16949367 28416635 31973889
MED21 MED14 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9734358 33961781 24981860 22939629 28514442
NSFL1C PLAA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRX UBXN7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CUL3 KLHL12 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
NSFL1C UBC â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
TERA CUL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22466964 26112410 28443643 18775313
VHL CUL2 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6542648 18323857
KLH12 CUL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17543862 16547521 32296183 21145461 29999490 18303015 27716508 30190310 25416956 19295130
ERCC8 DDB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12732143 22232169 26826127 29531219 17392787 16751180 16949367 31970402 28416769 22902626
MED7 MED21 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 24882805 26186194 28514442
NEDD8 RBX1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HIF1A UBC â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CUL2 ELOB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11384984 9122164 30166453 24981860 21145461 12048197 19327355 24076655 15601820 18173839 31253590 25661653 15966899 12149480
HIF1A ELOB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23401859 12050673 18323857 12004076 19940151 31253590 17353276
ELOB VHL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 7660122 17986458 24981860 14636579 26735018 12604794 10205047 22286099 18323857 10635329 17922844 18173839 15935760 31253590 17339318 28775317 7660130 22234250 32328410 12048197 9751722 16503656 10823831 27517496 9122164 17353931 18187417 20871634 15601820 15060148 25500545 26751167 28514442 30890701 10449727 12050673 10587522 20049704 12697815 12004076 19030229 24469044 21942715 25661653
HIF1A ELOC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17965024 12050673 17558023 18323857 12004076 19940151 17244529 17353276 21658608
ELOC VHL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 7660122 17986458 24981860 14636579 26735018 12604794 10205047 33137104 18323857 29401731 17922844 10635329 15935760 30267325 20300531 28775317 7660130 8674032 22234250 32328410 29121446 9751722 16503656 10823831 27517496 11739384 9122164 17353931 18187417 20871634 18305400 15601820 15060148 25500545 26751167 28514442 10421634 21685897 30890701 10449727 17558023 10587522 12697815 12004076 19030229 24469044 15611064 21942715 17244529 25661653
UBXN7 TERA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32296183 29599191 28274878 22466964 26389662 29540532 18775313
KEAP1 CUL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15367669 28186440 15572695 20864537 25742418 33130828 20534351 20027226 30765703 32854194 23727018 25628777 26757824 17439941 16449638 16790436 21357422 19818716 32341456 20421418 22245129 26219975 22558124 32296183 24896564 15983046 30383469 18251510 24127568 22911784 33391509 15282312 20865015 24322982 21145461 20599909 17822677 22448038 18417180 30273379 15601839
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28446751 34026424 29499938 22038470 19250909 26496610 31973889 12481031 30349055 24292684 30945288 33969670 27113764 32140073 33504946 12609982 25189618 23238014
MED31 DAZAP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VCP NPLOC4 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 20414249 7903886
CTDP1 GTF2B â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL4A VPRBP â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
TRIM8 UBXN7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ERCC3 GTF2F1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
ERCC3 POLR2B â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERCC3 POLR2I â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ERCC3 POLR2D â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2E2 POLR2I â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GTF2E2 POLR2D â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
UBB UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
MED6 POLR2I â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
NEDD8 SKP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
NEDD8 TCEB2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PLAA UBB â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KLHDC3 TCEB2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
UBQLN2 UBXN7 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
CUL1 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
NEDD8 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
VHL ELOB â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 6542648 18323857
MED14 POLR2B â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AMFR VCP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ELOF1 POLR2B â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ELOF1 SUPT5H â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ELOF1 POLR2D â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
UBC VCP â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
ELOF1 SUPT4H1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
GTF2B POLR2I â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
UBC UBR5 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
NPLOC4 UBC â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PSMD2 UBB â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ERCC3 GTF2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
MED14 POLR2D â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
CTDP1 POLR2B â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
GTF2B POLR2D â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
SUPT4H1 SUPT6H â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
GTF2B GTF2E2 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
MED7 POLR2B â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
MED14 MED31 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
POLR2I SUPT4H1 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
SUPT5H SUPT4H1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
MED31 MED6 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
CTDP1 GTF2F2 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
POLR2I SUPT5H â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
UBC UBQLN1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
GTF2E2 POLR2B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
POLR2D SUPT4H1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PSMD2 UBC â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
UBXN1 TERA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 29685906 26389662 15362974 21135095 27785701 25416956 29540532 18775313
ERCC3 GTF2F2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
VCP NSFL1C â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 20414249 7903886
GTF2F2 POLR2D â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
GTF2E2 GTF2F2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
GTF2E2 GTF2F1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
BIRC2 UBC â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
CUL2 ELOC â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11384984 9122164 10449727 31444342 30166453 21145461 23563313 26735018 24981860 19327355 24076655 29991678 15601820 19339690 17183367 9447969 25661653 15966899
ELOC ELOB â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 20211142 29401731 30166453 24981860 10205047 17997974 22939629 17922844 21516116 21822215 22863883 31253590 9447969 7660129 23333304 26344197 16675548 23988114 11739384 12149480 32296183 24402281 25416956 19159283 16189514 10224134 10449727 12050673 31444342 10587522 12004076
NPL4 TERA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 20414249 30344098 27913212 34262183 16234241 30335548 32814053 27762274 28320958 26389662 26549226 23293021 29599191 21645854 27226613 15371428 29540532 31623962 23333620 28443643 17872946 22232657 18586029 34739333 18775313
TERA UFD1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 20414249 26712280 27913212 18199748 23443559 16234241 28320958 26389662 26549226 31477623 29599191 27226613 15371428 19275885 29540532 23333620 28443643 24248593 27684549 17872946 22232657 34739333 16822850 16525503 18775313
HIF1A TCEB2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HIF1A TCEB1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
UBXN1 VCP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MED21 MED31 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
PLAA UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GTF2F1 POLR2D â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
POLR2D SUPT5H â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
GTF2F2 POLR2I â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
AMFR UBC â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CUL2 TCEB2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
GTF2F1 POLR2I â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
DDB1 ERCC8 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
GTF2B GTF2F2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
GTF2B POLR2B â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
POLR2B SUPT4H1 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
GTF2F1 POLR2B â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
MED14 MED6 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
MED10 MED21 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED10 MED31 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED14 MED21 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED14 MED7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED21 MED7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED21 MED6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MED6 MED7 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CUL2 RBX1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CTDP1 GTF2F1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ERCC3 GTF2E2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MED10 MED14 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MED31 MED7 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
GTF2B GTF2F1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
KEAP1 NFE2L2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MED10 MED7 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
MED10 MED6 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SUPT5H SUPT6H â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
UFD1L VCP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GTF2F2 POLR2B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NSFL1C VCP â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2B SUPT5H â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
POLR2D POLR2I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NPLOC4 UFD1L â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
SUPT4H1 SUPT5H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
TCEB1 TCEB2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
GTF2F1 GTF2F2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NPLOC4 VCP â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2D â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
POLR2B POLR2I â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CUL1 RBX1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RBX1 CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 154.0 1.0 Omnipath 17053147 12684064 20638939 11967263 19797085 19258535 26540345 18826954 15071497 15448697 21765416 25730849 10230406 23343194 21169563 22270359 19250909 23732914 11359933 12051714 20006983 15361859 10748083 19352404 22682247 18787170 12504025 18636226 16469695 15459660 20211143 10535940 15001769 26725323 19411070 11861641 26159692 16697054 1570337 19751508 22822056 11348595 7542250 7641885 19849719 16759355 12820959 17452440 19622404 15703371 10648623 19245792 23331499 9694792 19150432 23180781 19597341 16189514 22474075 18988627 22767593 17143292 24949976 10713156 23770852 22405651 19942853 18196958 20399188 16713974 26192618 11027288 17884153 19933270 22730322 21411632 11961546 17936032 19809470 15147722 19270156 19576224 11483504 20976471 12504026 24023259 12840033 15340381 12904573 20558317 11900249 14536078 19686080 12565873 18805092 15489953 19557001 26885856 17652783 12481031 20843316 11955436 21071413 16039586 11956208 20705860 8666229 17928543 10023660 19836308 16940750 12706828 19143635 15688063 10671552 16123592 19366350 19847258 12417738 11245432 20832730 12648680 12609982 19619488 10230407 18931676
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
RBX1 CUL2 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB2 CUL2 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
CUL2 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 CUL2 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB2 CUL2 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
CUL2 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
CUL2 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
CUL2 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
ELOC HIF1A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 11292861 9122164 10878807 12821933 12101228 11292862 10823831 11504942 11454738 10944113 11358837 11024059
NPL4 UFD1 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 32296183 11574150 20414249 24248593 17202270 26344197 21645854 22939629 18586029 28320958 15371428 26389662 16322459 18775313
CUL3 UFD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
RBX1 UFD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
KEAP1 UFD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
NFE2L2 UFD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
VCP UFD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23443559 16234241 26389662 16525503 18775313 26712280 27913212 15371428 20414249 26549226 16822850 18199748 23333620 17872946 19275885 24248593 20442859 27226613
NPLOC4 UFD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16322459 18775313 18586029 15371428 20414249 26389662 36087575 32296183 17202270 24248593 20442859 11574150
AMFR VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 20126661 22328510 16407162 16987818 17681147 26712280 16275660 21636303 17872946 18835813 19828134 22119785 23333620 23383273 26424800 21343306 21914798 16186510 15331598 17311810
SUPT4H1 CTDP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12653964 10757782 9857195 9450929
SUPT5H CTDP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12653964 10757782 9857195 9450929
GTF2F1 CTDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12732728 12591939 9765293
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
CUL3 NPLOC4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
CUL3 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
CUL3 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
CUL3 NFE2L2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
KEAP1 CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20534351 30273379 15983046 24896564 15282312 17439941 32341456 26219975 32296183 26757824
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
GTF2F2 ERCC3 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2E2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2B â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
ERCC3 GTF2F1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 Reactome 7151173 1310361 8490964 9405375 8156590 10723029 10024882 8946909
RBX1 ERCC8 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 22466611 24127601 23973375 22466612 20541997 22466610 23906714 16751180 22902626
GTF2F2 GTF2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7854423 11278533 31467278 11183778 8441635 16189514 8662660 7827505
RBX1 HIF1A â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 11292861 9122164 10878807 12821933 12101228 11292862 10823831 11504942 11454738 10944113 11358837 11024059
TCEB2 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
TCEB1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
RBX1 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
UBXN7 KEAP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
VCP KEAP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
KEAP1 NPLOC4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
RBX1 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
KEAP1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 104.0 1.0 Omnipath 30122040 17020408 31257023 35380342 16449638 22245129 18417180 28939422 15475350 24130096 20421418 12145307 32057361 17462537 23727018 24704364 34894983 23857982 19920073 31262713 20599909 36038548 24997453 17015834 23722832 21988832 30778200 24322982 36333711 20486933 30465941 22448038 30576774 21262351 23645672 16888629 31169361 11909699 26078718 25582950 19706542 20463144 16006525 18694732 11439354 15985429 15572695 34815381 28186440 23066931 19560419 15601839 23986495 25628777 27212020 22302998 30793592 16790436 26536456 24512214 17822677 20027226 28533375 22215675 29423025 14517290 32911434 20484052 14585973 18387606 23382044 21383067 32159343 18757741 27091842 24011591 9887101 31941496 22558124 36165926
RBX1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
UBXN7 NFE2L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
RBX1 NFE2L2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16790436 32284348 24366543 15601839 19321346 17081101 23986495 15367669 15572695 9887101 17785452 15282312
VCP NFE2L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
NFE2L2 NPLOC4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
RBX1 NFE2L2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
RBX1 NPLOC4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
VCP NPLOC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 34262183 31623962 20442859 32814053
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
VCP RBX1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
RBX1 TCEB2 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 SKP1 â—¼   PHYSICAL_INTERACTION 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 SKP1 â—¼   SHARES_COMPLEX 24.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
RBX1 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
RBX1 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
RBX1 TCEB2 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB2 TCEB1 â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB1 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
TCEB2 TCEB1 â—¼   SHARES_COMPLEX 21.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18420585 18931676 18985005 19622404 19622774 19686080 19809470 19847258
TCEB1 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
TCEB2 VHL â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
TCEB2 VHL â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258