Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
YWHAG ARHGEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
TP53 BHLHE40 â—¼   COLOCALIZATION 2.0 0.8 intact 17347673 5219751
TP53 BRCA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003689107 20421506
FOXM1 BRCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20068070 17101782
FOXM1 BRCA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17101782
XPO1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19940019 18573912
CTNNB1 NANOG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 32448362 25921273
GLI1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19329935 19930158
DDX58 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
DDX58 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
IFIH1 DHX58 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0606699104 17190814
FOXO3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20439537 20467422
FOXP3 SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18008005 24155921
GLI1 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20581804
GLI2 NANOG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20581804
IFIH1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
YWHAG MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MPP1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TCF7 NANOG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 32448362 25921273
UCHL1 RPS27A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 20439756
UBC SNAI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7718905 20385133
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
UCHL1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
XPO1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17268548 17891139
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBA52 USP21 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UCHL1 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2D1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22842904 21857666
UBC YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
MARK3 YWHAH â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
DDX58 RPS27A â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
CUL3 RBM45 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25939382 21145461
DHX58 DDX58 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17190814 31237466
SKP2 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HIST2H2AA3 RPS27A â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST2H2AA3 UBA52 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
HIST2H2AA3 UBC â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
HIST2H2AA3 UBB â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
RPS27A UBE2S â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
UBB UBE2D1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
KCTD6 CUL3 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27152988
TRAF6 UCHL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23717208 32814053 17353931
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBB UCHL1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
UBA52 UBE2S â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
NANOG USP21 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
TP53 UBE2D1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
UBB USP21 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
TP53 XPO1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MARK2 YWHAH â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
CTNNB1 TCF7 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CDC34 SKP2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CUL3 KCTD6 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MARK2 MARK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 32707033
UBA52 UBE2D1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RPS27A USP21 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
UCHL1 UBC â—¼   CLEAVAGE ✅ + 0.87 0.87 Signor 9521656
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CUL3 KCTD9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 21145461 25416956 26334369 33130828 28514442
CDC34 UBB â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
DDX58 UBC â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
RAD51 TP53 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MARK2 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22072711
CTNNB1 TCF7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15473860 17724465 10489374
DHX58 IFIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17020950
MAPK3 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19282669
GATA3 FOXP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21965331 21131965 18162042
FOXP3 USP21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20554955 23395819
TP53 NANOG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18371449 20631301 15619621
YWHAH MARK2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 19553522 8009002 0803887
UPF3B RBM8A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 12718880 5216341
RPS27A UBE2D1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
RPS27A TRAF6 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
UBB UBE2S â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
UBA52 UCHL1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
RPS27A UCHL1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
UBC UBE2D1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
UBC UBE2S â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RAD51 BRCA2 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219969 17541404
UBC USP21 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
CDC34 UBC â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
UBC UCHL1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RPS27A TP53 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RBM8A UPF3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
STUB1 UBE2D1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TP53 MAP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10521394 10446979 19411072 10990460 8956998
MARK1 MAP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 19651622 19415658 20058876 17081983 20166139 18767875 20068231 18707149 18452278 17693683 8631898 18212344 10542369 18669648
MAPK3 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 28096473 24043311 18211802 19261619
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
TP53 BHLHE40 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22723347 17347673
BRCA2 RAD51 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
BRCA2 RAD51 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 10858305 10931916 11571269 11756412 11850621 11877377 11927554 12239151 12551922 12607003 12947387 14624239 14726013 15220350 15459660 15590677 15650050 15703371 16337602 16697054 17303408 17349954 18082604 18082605 18085520 18087292 18584027 18660752 18809224 18931676 19075014 19217432 19264559 19473888 19525936 19622404 19686080 1974050 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 21376743 21574959 22021614 22101340 22505525 22743550 22751496 22771115 23414611 23444773 24050180 9488723
TP53 BRCA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9619832 11295099 18765668 12591928
BRCA2 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 87.0 1.0 Omnipath 17145710 21601571 15937124 17541404 11313963 16914443 26145171 21670257 18264088 19303847 25585578 12815053 16793542 21789034 25282148 17515904 9126738 20729859 15703751 21076401 15065660 22293751 19875419 12606939 22116401 12619154 23935068 15800615 33476590 15800651 15671039 11477095 16513631 9811893 10551859 20729832 9523196 14636569 17515903 12442171 9405383 26833090 21399666 19628690 9560268 10373512 14580352
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
CTNNB1 TCF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 25678599 19358846 16442529 15735151 17143293 9065401
CTNNB1 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 15905404 21071413 17254970
GLI2 CUL3 â—¼   PHYSICAL_INTERACTION 18.0 1.0 Reactome 15198976 19852954 20360384 21878643 19684112 9874371 16651542 15115751 19955409 20154143 20487519 20014402 20956384 19818708 16740475 24072710 14528312 23955340
DHX58 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17190814 16116171 17020950 16210631
FOXM1 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16585184 16314512
GLI1 SNAI1 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11001584 11960000 12138125 14555646 15087129 15520176 16054035 16158046 16328026 16396903 16406505 16571352 16880536 17000779 17035233 17638910 18754008 18813803 19081070 19190345 19219074 19736394 20107231 21059263 21442356 22354771 23031257
GLI2 GLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16571352 15175043 12165851 9636069
GLI2 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18813803 16880536 19190345 18698484 15087129 17845852 19049965 11001584 20107231 20712011 15520176 16406505 17000779 16413481 16571352 16396903 9609833 18497536 14555646 9216996 20581804 11493558 15140221 16054035 20143239
GLI1 SNAI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16158046 18813803 19219074 16880536 21059263 11960000 19190345 15087129 21442356 16328026 19736394 11001584 12138125 20107231 15520176 16406505 17000779 16571352 16396903 14555646 17035233 16054035
MAPK3 MARK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MARK2 UTRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19945424
TP53 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513613 16322760 20802511 16398215 18769160
TP53 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 8617246 11002423 16713569 16322760 16983346 9380510
UBE2D1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
TP53 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18172499 18695251 24667498 22056774 17290220 17592138 12421820 18413597 20173098 19556538 21857681 17470788 18359851 19805293 19196987 12640129
UCHL1 UBC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23801757 22284438 20622874 16169070 20439756 9521656 2532544 27066941