Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PRKACA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APPBP2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SYK APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GAPDH CDC73 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CUL3 TNFAIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19782033 25416956
DDX58 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
DDX58 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
DDX58 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
PRKACA GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HIF1A SUMO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7941484 19680224
HIF1A PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18340011 19648120
MAVS UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MAVS TGFBR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAVS UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PRKACA USP25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF2 RAD23A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RAD23B SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23751493 26151477
RAD23B SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23751493 26151477
RAD23B SUMO3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23751493 26151477
SUMO3 SENP1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 22878415 8402547
SENP1 SUMO1 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 22878415 8402547
UBE2I SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
USP25 SKIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SUMO3 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11451954 17938407
TGFBR2 USP25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TRAF3 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
KLHL13 KLHL9 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
CUL3 BTBD9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33130828 21145461
CUL4B UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28225217 21145461
NEDD8 SYK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24654937 18274552
MYO6 UBB â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
UBB USP28 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
USP25 SYK â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
CUL3 KLHL13 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
MAVS TRAF5 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
NEDD8 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
TRAF5 TRAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32296183 9718306 21903422
SYK USP25 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
SUMO1 SUMO3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 25027693 17938407 21098080 15576338
HIF1A CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23401859 27320910 18323857 17439941 17132228 19940151
KCTD10 KCTD13 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SUMO1 SENP1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8402547 22878415
SUMO1 SENP1 â—¼   CLEAVAGE ✅ 0.87 0.87 mint 8402547 22878415
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
KCTD10 TNFAIP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RAD23B UBB â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAVS TRAF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TRAF3 TRAF5 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
KCTD13 TNFAIP1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
TRAF6 TRAF5 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8153045 21516116
TRAF5 TRAF6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27107012 32296183 29176576 21516116 25416956 22493164 33539883
CUL3 KCTD10 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CUL3 KCTD13 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
UBC USP25 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MAVS DDX58 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17190814 19454348 30193849 20007272 20406818 20434986 30558248 21292167 28594325 20080758 16177806 18200010 29053956 22301138 22022264 16153868 29263274 26494172 26061460 33372174 16585524 31433974 21844353 19164550 30267576 22623778 33976430 20071582 16127453 21903422 20554965 34544279 21102435 24478431 33649232 32612200 22114345 19193793 17709747
DDX58 UBC â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
HIF1A UBC â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
GAPDH ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
APP GAPDH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21832049 16713569 8473906
CUL3 KCTD10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21145461 19782033 32296183
CUL3 KCTD13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19782033 32296183 25416956
DDX58 TRAF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF6 MAVS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31390091 21903422 32511263 20080758 30527812 26221961 31806368 23545497 22908223 29125880 26385923 16153868 27348524
SUMO1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18093978
SENP1 SUMO3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MAVS TRAF3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
NEDD8 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
RAD23A UBB â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RAD23B UBC â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SUMO1 HIF1A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 20661221 24434214 20026589 17938407 15465032 15876874
TRAF3 MAVS â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 22792062 26221961 23545497 22908223 19893624 20080758 30527812 24622840 29125880 22022264 22079989 31390091 33411856 16858409 30267576 22901541 21200404 32324863 33608556 19419966 32511263 31806368 26519536 27980081 32366851 33582548 27348524
UBE2I SUMO1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5219915 17491593
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
SUMO3 UBE2I â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MYO6 UBC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
UBC USP28 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAVS TRAF6 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
DDX58 MAVS â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
SENP1 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RAD23A UBC â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SUMO1 UBE2I â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SENP1 SUMO2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
SUMO2 UBE2I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL2 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
DDX58 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 20554965 16127453 33372174 20007272 35075101 21419663 16585524 20406818 19052324 17020950 21903422 19164550 24478431 17190814 16713980 18200010 18948594 19193793 16177806 34544279 16153868 23843640 16785313 16301520 21844353 16125763 19036819 18977754 21102435 33976430 22301138 17709747 21200404 29263274 26494172 23499489 18207245 19881509 22844514 20080758
DDX58 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17020950 16306936 16858409 21844353
HIF1A GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19828020 12193088 15967517 21338575 11955624 15132953
MAVS TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22901541 19893624 17020950 18818105 21200404 16306936 18207245 19546225 22844514 22792062 19193783 34610835 16858409
SUMO2 SENP1 â—¼   CLEAVAGE ✅ 9.0 1.0 Reactome 16253240 16608850 15487983 16738315 16738331 12192048 11896061 17591783 14563852
UBE2I SUMO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 21212807 25416956 16713569 18691969 17938407 11735126 25502805 15931224 26496610 16732283 24352468 17353931 18359863 10666456 21174150 8921390 9353268 12924945 21949651 32296183 16524884 17956732 18264111 12764129 10961991 14673145 19684601 17698038 16494873 31515488 23871147 17491593
TGFBR2 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFBR2 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 12717440 19050695 11133108 14557817 19920116 22710166 19114990 12767520 22703233 23331499 11013220 20060931 17934056 21614932 17673906 20644162 24132110 18922473 9865696 22943793 20519943 21900405 12154066 7594497 18758450 15548370 24336330 21278795 12724770 19010789 15265520 16474430 26192618 12809600 19109155