Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GDF9 TRIB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GDF9 TDGF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAC3 XIAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22117219 8313544
SMURF2 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF2 SMAD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF2 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF2 FHL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18157088 6492033
SMURF2 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 14722617 15265520
MIR17HG BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19390056
ACVR2B ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
SMAD7 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10564272 23331499
ACVR2A ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9748228 8612709
BMP8B ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10504300
BMPR1B ACVR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
SMAD7 ACVR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMAD6 ACVR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMAD6 ACVR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
BMPR1B ACVR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
SMAD7 ACVR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
BMPR1A ACVR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7644468 7791754
ACVR2B BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16446785
ATF2 RHOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11160903 21565167
SMAD7 BMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMAD6 BMP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
GATA4 BMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23632743 24866243
SMAD1 BMP7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20375015 17127702
BMP8B BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10504300
SMAD7 BMPR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMAD6 BMPR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMURF1 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 17317136
SMAD7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10564272 23331499
SMAD6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10564272 23331499
NOG BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 12478285
BMPR1A BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10712517
BMPR1A SMAD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19620713 11792802
BMPR1B SMAD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
BMPR1B SMAD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19620713 11792802
SMAD6 BMPR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
SMAD7 BMPR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
NOG BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 12478285
SMURF1 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22298955 17317136
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
SP3 CD83 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12182451
CREB1 FST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15130492 17482756
CREB1 FST â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17482756
CREB1 SMAD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
NOG GDF5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21976273 19956691
PRKCB MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12917261 9891069
XIAP RAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22117219 8313544
ZFYVE16 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMURF1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
XIAP TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
XIAP TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12048196
GATA4 NKX2-5 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ACVR1 BMP7 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
SMAD6 SMURF1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ACVR1 BMPR2 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MRAP2 BMR1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRIQ1 BMR1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMAD7 BMR1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15148321 20663871
CD83 BMR1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRIQ1 BMPR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRIQ1 ACVR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MRAP2 ACVR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD83 BMPR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MRAP2 BMPR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
TAB1 MAP3K7 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5218828 16845370
MAP3K7 NLK â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
BMR1B SMAD6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15761153 11483516 9436979
BMPR2 BMP6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11401330 10504300
SMAD7 TAB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12589052 11737269
SMURF1 SMAD6 â—¼   RELOCALIZATION ✅ - 0.83 0.83 Signor 22298955
SMAD5 ACVR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10652350 10583507 9748228 16189514
CAV1 TRPC1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
BMR1B BMPR2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7791754 10712517
SMAD1 SMAD6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
BMR1A BMP6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11401330 18070108 10504300
BMR1A BMP7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 7791754 18070108 8006002 8605097 16189514
BMR1B BMP7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8006002 18070108 8605097
BMP7 ACVR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18070108 8006002 16189514
ACVR2B TGFBR1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
ACVR2B BMPR1A â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
BMR1A BMPR2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 7791754 10712517
SMAD7 SMAD6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26555259 9256479
ACVR2B BMP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SMURF2 SMAD7 â—¼   UBIQUITINATION ✅ - 0.87 0.87 Signor 18448069
SMAD7 SMURF2 â—¼   RELOCALIZATION ✅ + 0.87 0.87 Signor 19352540
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SMURF1 SMURF2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
TAB1 XIAP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
ACVR1 BMR1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 18436533 26186194
BMP4 BMPR2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BMPR2 BMP7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7644468 7791754
GDF5 BMPR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19229295 9525338
SMAD6 CTBP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24850914 14645520
BMP2 BMPR1B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ACVR2A INHBA â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
BMPR2 ACVR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7890683 7791754 28514442
BMPR2 BMP4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7644468 12045205 28126904 8702914 7673243
INHBA FST â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7887917 16198295
SMAD6 SMAD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9256479 12857866 9436979 11483516
SMURF2 TGFBR1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
BMPR1A GDF5 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
SMAD1 SMURF2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
ACVR2A BMPR1A â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
SMAD5 SMURF1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
SMURF1 SMAD7 â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 12519765
SMAD7 SMURF1 â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 19352540
TAB1 TAB2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
BMPR1B SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
ACVR2B SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
BMPR2 SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
ACVR2A SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
BMP2 SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
BMPR1A SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
BMR1A BMP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21054789 18070108 25938661 19804412 20860622 15064755 10881198 10880444 10712517 16672363 11263668 10692589
BMR1A BMP4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7644468 21054789 11241215 28126904 8006002 8702914 27684187 20860622 16189514
BMR1A GDF5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19229295 21543859 11282024 16127465 9525338
BMR1B GDF5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19229295 16127465 9525338 11282024
BMR1B BMP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18070108 19229295 15064755 10712517 7811286 9872992
SMAD6 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23455153 23331499 10564272
ACVR1 SMAD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10583507 16189514 11792802
ACVR2A ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12682303 9032295 8612709
ACVR2A ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
ACVR2A SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
ACVR2B SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
ACVR2B ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
ACVR2B BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 17295905 16446785
BMPR2 BMP2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25938661 7791754 10712517 10880444
BMP2 ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
BMP2 SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
NOG BMP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10657699 12700180 11706034
BMPR1A ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
BMPR1B GDF5 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BMPR1B ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
SMAD6 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10564272 23331499 15761153
SMAD7 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10564272 23331499 15761153
MAPK8 BMPR2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BMPR2 ZFYVE16 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17356069 8893010 9136927
TRPC1 CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19897728 19052258 10980191 12732636
SP3 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19197985 19011236 19994725
RHOC LIMK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11018042 16219803 10652353
LIMK1 RHOB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11018042 16219803 10652353
XIAP MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11865055 12048196
SMURF1 SMAD6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278251 22298955 29950561
TGFBR1 SMURF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15496141 11163210 11278251
ATF2 MAPK8 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
BMP4 BMPR1A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
BMP7 NOG â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
BMR1B BMP4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 8006002 8702914 7811286 11282024
ACVR2A BMP7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
FST INHBA â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ACVR2B INHBA â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ACVR2A BMP2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
BMPR1A BMP2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 19804412 7261592
SMAD7 SMURF2 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SMAD1 SMURF1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SMAD7 SMURF1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
BMP2 BMPR1A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
MAP3K7 TAB2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GDF9 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12135884 10712517
GDF9 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14684852 14514671 27252362
GDF9 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12135884
GDF9 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12135884
GDF9 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1213588412135880 12135884
BMP10 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16049014
BMP10 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
BMP10 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30246251 30246252 27252362 31127068
BMP10 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15621726 16049014
BMP10 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15621726 31127068 16049014
INHBB ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9202237
INHBB ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11266516 1246619011266510 12466190
INHBB ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11266516
INHBB ACVR2B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11117535 8196624 15123686 8622651 9032295
INHBB FST â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 7678220 8033815 12697670 1592877 16198295
INHBB ACVR1B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11117535 8196624 15123686 8622651 9032295
INHBB ACVR2A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11117535 8196624 15123686 8622651 9032295
INHBB ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11266516 15196700 12032389
BMP5 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11580864 16189514
SMAD7 SMURF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 26435193 22773947 15231748 23331499 22921829 16641086 17719543 21791611 26679521 11163210 27292644 20937913 15221015 18448069 22624557 32283253 23973329 16061177 14722617 19352540
SMURF2 SMAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20484049 15221015 22298955 15231748
SMURF2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 14701756 23331499 15221015 11016919 22298955 11158580 32296183 15231748 20937913
SMURF2 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11278251 15221015 22921829 22624557 9335505 21897371 22286770 14722617 9335507 17317136 15761153 12151385 11163210 9215638
GDF2 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 27252362 19996292
INHBA ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16189514 11266516
AMH ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14656470
BMP2 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8006002 28977600
BMP6 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12297674
BMP7 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11282024 8006002 31619522 122976748006002 16189514 12297674
BMPR2 ACVR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 21071413 16446785 7791754 7890683
ACVR1 SMAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9748228 23331499 10652350 10583507 16189514 11792802 10504300
ACVR1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 19651622 9748228 23331499 9335504 10085121 10652350 9136927 10583507 16189514 11792802 18988627
INHBA ACVR1B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11117535 8196624 15123686 8622651 9032295
GDF1 ACVR1B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
INHBA ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 81675688397373 8167568 8397373 16189514 9605406 7890768
ACVR2B ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 23180781 8622651 16446785 12364468 18988627
TDGF1 ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19874624 11909953
INHBA ACVR2A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11117535 8196624 15123686 8622651 9032295
ACVR2A GDF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
BMP2 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17483092 10880444 21702718 17295905 25938661 20959140
BMP6 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10504300
GDF5 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8702914
BMP7 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9748228 7790373 12667445
INHBA ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11266516 10746731 1646080 11266510 24018044 9605406 12466190
GDF2 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22622516 19996292
TDGF1 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12682303
GDF7 ACVR2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
INHBA ACVR2B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11117535 8196624 15123686 8622651 9032295
GDF1 ACVR2B â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
GDF2 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15851468 27252362 26047946
BMP7 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9748228 23331499 16446785
GDF5 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 8702914 16446785
INHBA ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 8622651 16446785 9202237
BMP2 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 20385559 16446785 28977600 15064755 18988627 17295905
BMP6 ACVR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 21071413 16446785 10504300
MAPK8 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 11279118 17081983 20506250 12958075 9162092 19255142 8654373 20028971 15105425 17626013 12788955 11566021 15550563 10777545 23331499 7535770 15068801 21071413 17875713 9317150 16393692 15304344 18988627 7737130 26538579 21444723 602896 11896587 12110590 7824938 11274345 12874243 11971971 9399639 19436832 16533805 9670022 9029150 11865055 9207092 12804775 7737129 15212693 9405416
BMP15 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15621726 12044914 12419820 1204491412419820
BMP15 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15621726 23331499 12419820 16446785
SMAD1 BMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14551209 11786386 21471203 19836350 11585340 22072987
NOG BMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10657699 12700180 19804412 15064755
BMP2 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10880440 23331499 11263668 23180781 18342887 16446785 10880444 10712517 7791754 17295905 25938661 24337809
BMP2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 17145710 17483092 10880444 10712517 26330344 21054789 16672363 10881198 11263668 20860622 15064755 18937504 25938661 15621726 12700180 10692589 19804412
BMP2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7811286 12700180 9872992 10712517 15064755 19229295
BMP4 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 8702914 26330344 20860622 21054789 11241215 8006002 16189514 7644468
BMP4 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7811286 8702914 11282024 8006002
BMP4 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8702914 23331499 21071413 16446785 12045205 8006002 7673243 7644468
BMP6 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 16446785 11401330 10504300
BMP6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11401330 12297674 10504300
BMP6 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11401330 10504300
NOG BMP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17145710 12478285
BMP7 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15621726 106311828605097 8605097 10631182
BMP7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16189514 7791754 12297674 8605097
BMP7 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18342887 16446785 7791754 7644468
CTDNEP1 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 17141153
GDF7 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
GDF5 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 21543859 9525338 11282024 16127465 19229295
BMPR2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18756288 7791754 10712517
GDF6 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9525338 160490149525338 16049014
BMPR1A SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11438941 24412244 19620713 9136927 16189514 11792802
GDF5 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8702914 15890363 9525338 11282024 16127465 15569154 19229295
BMPR2 BMPR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 21071413 16446785 18756288 10712517 7791754
BMPR1B SMAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 19620713 9766532 11792802
BMPR1B SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9748228 23331499 9335504 10085121 19620713 9766532 9136927 11792802 15212693
GDF2 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 28646109 15851468
GDF5 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8702914 23331499 9525338 23180781 18342887 16446785 19229295 87029149525338
GDF6 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 9525338 16446785 18988627 160490149525338 16049014
GDF7 BMPR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16049014
CAV1 TGFBR1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CAV1 TRPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14551243 10980191 16822931 19351713 18430726 19052258 12732636 19897728
MAPK8 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 28532298 14567915 17496919 19591900 21372320 19788416 15708980 8608010 16984892 20512932 20220133 21438496 20054826 19616017 23762064 15611655
TGFBR1 ENG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12015308 16785228 30761306 20042635 24319055
FST INHBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16198295 24627466 7887917 22037168
NKX2-5 GATA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19479054 15653675 16137232
TDGF1 GDF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15485907 21229555 21356369 15150278 15531507
HRAS MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11525649 8137421 16810318 16713569
KIT STAT3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
PRKCB KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 17570479 12040186 7693453 19568798 15567848 14585353
TAB2 MAP3K7 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TAB2 MAP3K7 â—¼   SHARES_COMPLEX 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TAB1 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16289117 18180283 10838074 24912525 23934659 10882101 19556242 11259596 19026643 14670075 17299140 23331499 22158122 12372426 21903422 17560374 21071413 23180781 19775907 14743216 17348859 20200282 26432169 18988627 10094049 8638164 11809792 10702308 25241761 19232515 14633987 18456659 10921914 20538596 15590691 16845370 27468689 12975377 12242293 17172402 22167179 12429732 12624112 12859960 16260783 11460167
SMAD7 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12589052
SMAD6 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11737269 10748100
TAB2 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 112.0 1.0 Omnipath 17145710 11477091 17301840 18180283 10838074 24912525 16251197 10882101 19556242 15125833 19955178 31250519 36130827 17363905 17158449 11259596 19026643 24699077 14670075 18641653 24061540 24403530 23331499 22158122 12372426 21903422 27426733 21071413 23180781 14743216 18021073 21133840 20200282 26432169 21232017 18264787 20194509 10391247 18988627 22081109 8638164 16799562 11809792 19232515 12620219 14633987 19161412 20538596 22941947 23681101 20932475 15590691 12609980 16845370 27468689 12242293 11280761 15082531 26192618 14660645 24958845 17172402 15327770 25642820 22167179 20164171 16603398 17384642 11460167 21041997
MAP3K7 MAPK8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15692051 17947236 11865055 17965022 17186025
MAP3K7 NLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 17145710 11071635 23331499 15082531 25241761 12482967 15764709 11404460 15640443 20194509 10391247 10823839 7693453 12709429 10377264
MAPK8 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 23255093 17502367 21702955 19413330 11335711 9343414 23331499 15465816 12576423 11350938 20068231 12763138 9872331 18491316 18669648 10521505 18691976 20058876 15979846 14551213 10446219
TAB2 NLK â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10391247 11274345 12620219 14660645 14960582 15082531 18264787 18855897 20194509 23070005
TAB1 NLK â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10391247 11274345 12620219 14660645 14960582 15082531 18264787 18855897 20194509 23070005
TAB1 NLK â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 10391247 11274345 12620219 14660645 14960582 15082531 18264787 18855897 20194509 23070005
TAB2 NLK â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 10391247 11274345 12620219 14660645 14960582 15082531 18264787 18855897 20194509 23070005
NLK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17563747 17145710 15764709 15004007
SMAD1 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10692396 17215250 22219353 22072987
SMAD6 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9256479 9335505 9436979 21071413 18988627 11483516 12857866
TGFBR1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19651622 9748228 9335504 10085121 9136927 15212693
SMURF1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 14701756 17676934 15221015 19914168 21708152 22298955 24828823 19917253 16611643 17510966 15761153 22670624 22152476 17289590 15231748 21685363 27447855
SMAD5 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10692396 16436528 22219353
SMURF1 SMAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17676934 20484049 11278251 15221015 19914168 22298955 18641638 22670624 15231748 12857866
SMAD6 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11737269
SMAD6 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11278251 23331499 22921829 9335505 21897371 22286770 20663871 9335507 15761153 12151385 11163210 9215638 9892110
SMAD7 TGFBR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11279127 15265520 22286770 23784029
SMAD7 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11279127 15265520 22286770 23784029
SMURF1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 22773947 12151385 23331499 22921829 21071413 18988627 11278251 12408818 12519765 22152476 27292644 20937913 15221015 24700460 14722617 16720724 23959799
SMAD7 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 9335505 21897371 9335507 17314099 12151385 9892110 23331499 22921829 21071413 21791611 18988627 11278251 16571110 14657019 18725536 15761153 11163210 15221015 30017632 22286770 15148321 20663871 14722617 9215638
SMAD7 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11737269
SMAD7 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 17384642
SMURF1 TGFBR1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 14657501 14722617 14744429 15265520 15761148 21572392 22949611
SMURF1 TGFBR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9335505 21897371 9335507 17317136 22949611 12151385 12857866 23331499 22921829 11278251 21572392 14657019 12519765 15761153 11163210 15221015 15761148 22286770 9215638
TAB2 TAB1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
TAB2 TAB1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
XIAP TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9878061 12048196 17560374 27107012 11865055 23818254