Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AURKA HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17604723
CASC3 SNRPA1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CASC3 SNW1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CASC3 PPIL1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CDH13 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DNMT3B CDH13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17631504 16537533
SP1 CDH13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18182775 7933089
HTT CREB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10775268
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HIF1A ITGB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 23640055
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19132225 20001745
PSMD4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNW1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
INO80E HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NHP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
INSIG1 SERBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18786561
SP1 MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18173747
PPIL1 RBM42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PPIL1 PPP1R8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SF3A2 PPP1R8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219711 17332742
UBAP2L PRRC2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14667819 5216829
RBM42 SNRPA1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RBM42 SF3A2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RBM8A SNRPA1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RBM8A SNW1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SP3 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9677424 9325332
PPIL1 RBM8A â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
SF3A2 SNW1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SP3 SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12414801 11517158 10825178 16734381 9329821 23825960 12200149 15247906
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
WIBG CASC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PPIL1 SF3A2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
BUD13 PPIL1 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
INO80E NFRKB â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SF3A2 SMNDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
APBB1 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HIF1A TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18178340 21176881
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
SP1 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9677424 9325332 8955122
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
PPIL1 SNW1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
SF3A2 SNW1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BUD13 SNW1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
BUD13 SNRPA1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BUD13 SF3A2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
PPIL1 SNRPA1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL23 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RBM8A WIBG â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SNRPA1 SNW1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CASC3 RBM8A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SF3A2 SNRPA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
HIF1A AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18562694 19828020
RAC1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19751508 28626389 26403202 19417647 22270359 16212495 16940750 12480336 11152757 29497040 30650643 19020303 15377999
SP1 ZNF143 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 11856838 9705341 8668525 1829677 9009278 9153304 1535687 1739980 12414730
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
MDC1 ANXA1 â—¼   KO_UP_REGULATES ✅ + 3.97 3.97 PKG 28854368