Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PAX8 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8521821
FOXI1 PAX8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12702667
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
ERG AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8388477 22531786
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
GATA2 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24423874
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
AR HOXC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21047772 20610535
ASH2L SMAD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ETS2 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7731694
FLI1 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
GATA3 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21536859
ETS1 ERG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7731694
ERG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25277175 20820186
ETV4 ETS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8247540
ETS2 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9334186 16189514
FOS ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8557686
ETS2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8649821 10510472
ETS2 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19829305
NFIA ETV5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIX ETV5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
NFIB ETV5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 31838646
ETV6 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17606295 19829305
MYC FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20638938 19366810
SMAD9 FLI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
KLF15 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
RB1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1909121 7680889
FOS SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9988737
RB1 GATA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000123 19513100
GATA3 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22446486 12027437
SRF GATA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11003651 11158291
HOXA1 TBR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HOXA10 PHGDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19778996
HOXA5 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXA7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19918835
HOXA7 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC4 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
IRF4 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22446486 16272311
NCOA6 KDM6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810100105 19047629
KDM6A SMAD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
YY1 KDM6A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
KDM6A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20123895
PPARG KLF15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20592862
TP53 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10749849 16713569
KLF5 SOX9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23266329 24440658
NCOA6 KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17021013 0607313103
TP53 KMT2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
KMT2D SMAD9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
MAFB MAFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24520122 18199433
MYOD1 MAFB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10721736 10642889
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
NFIA MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32991581
POU5F1 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21425413 22153073
PPARG MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16838108 11477074
MYOD1 SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17194702 17043109
RB1 MYOD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21902831 8381715
TP53 NCOA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
NFIA NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
NFIB NFIX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29106906
TP53 PAGR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19039327 7013322
PAX6 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23622063 15558475
TP53 PAXIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
SPI1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14559995 12588990
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
RB1 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8434021
SMARCA4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11950834 33476981
ZBTB16 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24821728 24821727
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
GATA4 NKX2-5 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ASH2L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DPY30 HIST2H3C â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
KMT2C NCOA6 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
GATA1 SPI1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10364157 12202480
HIST2H3C RBBP5 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
HOXA5 HOXC4 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
ANDR PA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33640491 23161582
ANDR DPY30 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33640491 32814769
PPARG PAXI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 24368734
MLL3 DPY30 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31485071 26324722 24981860
PPARG ASH2L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19047629 24368734
SOX2 ASH2L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30089852 35140242
KLF4 KDM6A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22801502 35140242
MYC MATR3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC WDR82 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
PAX9 TLE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20211142
PPARG RBBP5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19047629 24368734
RBBP5 SOX2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30089852 35140242
SOX2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
HIST2H3C KMT2C â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
NCOA6 MLL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17178841 24981860 17021013 12482968 32350066
MLL2 PAXI1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17500065 17178841 17925232 24981860
PA1 MLL3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 17500065 24981860
PA1 DPY30 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 17500065 24981860
PA1 NCOA6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 17500065 24981860
KDM6A MLL3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17761849 29785026 24981860
KDM6A DPY30 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29785026 17178841 24981860
MAFB FOS â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
SOX2 KDM6A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22801502 35140242 28794006
SOX2 NFIB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 28794006 21532573
WDR5 SOX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30089852 29383478 35140242
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HIST2H3C SOX2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ANDR ERG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20478527 22722839
SMARCA4 TP53 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
FBXW7 KLF5 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
ETS2 ETS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16189514 9334186
HNF4A NCOA6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18552123 15604093 35140242 21292004
WDR5 KMT2D â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
TLX1 TLE1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 35140242 19250647
TLE1 TLX3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 35140242 20211142 19250647
KDM6A MEOX2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
ASH2L PAXIP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ANDR ASH2L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33640491 22722839
WDR5 PAXIP1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 24981860
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
IRF8 SPI1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ANDR MLL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32814769 33640491 28611094 22722839
MLL2 PA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17178841 24981860 23508102 17500065
KDM6A MLL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17178841 24981860 17761849 29785026 32350066 24491801
PA1 ASH2L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23508102 17500065 24981860
PA1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23508102 17500065 24981860
PAX6 ANDR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19790232 21935435
ANDR KDM6A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 34585037 33640491 22722839
PAXI1 MLL3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17500065 17925232 24981860
PAXI1 NCOA6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17178841 24981860 17500065 19047629 17925232 19433796
PAXI1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17178841 24981860 23508102 17500065 17925232 31076518
WDR82 ASH2L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 23508102 23870121 20516061 31076518
NCOA6 DPY30 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19047629 17500065 24981860
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
NCOA6 WDR5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
NFIB NFIA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26871637 35140242
RB1 SMARCA4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NCOA6 RBBP5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PA1 WDR5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24981860 23508102 17500065 19124460 27705803
NCOA6 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33640491 14645241
ETV5 ANDR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11509567 8798622
NCOA6 ASH2L â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 17178841 24981860 12482968 23870121 23508102 17500065 19047629 17925232 19433796 34079125
GATA4 SRF â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11003651 11158291
NCOA6 PPARG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19596656 11877444 19047629 15604093 10788465 24368734
PAXIP1 WDR5 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PAXI1 ASH2L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17178841 24981860 23508102 17500065 17925232 34079125
KDM6A PAXI1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17178841 24981860 17761849 29785026 17500065 17925232
PAXI1 DPY30 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17178841 17500065 24981860
PAXI1 PAX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10908331 35140242
KDM6A ASH2L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20305087 17178841 24981860 17761849 23508102 29785026 17825402 31076518 34079125
HNF1B HNF1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10484768 35140242 33961781 2044952
HOXC8 LHX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
KDM6A NCOA6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
WDR82 RBBP5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 23508102 23870121 20516061 31076518
SRF TEAD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11136726 12061776
ASH2L NCOA6 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
KDM6A KMT2C â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
WDR5 MLL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24788516 33961781 17178841 24981860 15960974 16603732 24491801 27705803 22665483 33022573 27563068 30604749 15960975 22689669 28514442 32350066 17500065 26186194 17925232 30107592 22266653
PA1 PAXI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17178841 24981860 23508102 17500065 19124460
PAXI1 WDR5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17178841 24981860 17500065 26186194 17925232 27705803 28514442
RBBP5 MLL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26324722 24981860 27563068 12482968 23508102 29785026 17500065 26886794 30604749 31076518
ASH2L MLL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20305087 26324722 24981860 27563068 12482968 23870121 23508102 17500065 26886794 30604749 34079125
NCOA6 MLL3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 17021013 12482968 23870121 19047629 19433796
MLL3 WDR5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26324722 24981860 27563068 17500065 30604749 27705803 33022573 22665483 22266653
NCOA6 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14645241
MYC DPY30 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ETS1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11991951 19829305
TP53 ETS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15469934 14586398
TP53 FBXW7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23518350 19366810 12824889
TP53 FBXW7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31346036 12824889
GATA1 FLI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10364157 12556498 12724402 16189514
PPARG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10678274 23657115 18059282
SPI1 GATA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18250304 10411939 10364157
HOXA11 HOXA10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17688409
WDR5 KMT2B â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
NFIC NFIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 9099724 25258084 28514442 16189514
NFIB NFIX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 9099724 26871637 28514442
NFIB NFIX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9099724
PAX6 PAX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10804178 11003833 12721955
PAX2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8521821 16320598
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
YY1 WDR82 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
KDM6A WDR5 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP5 WDR82 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
MEOX2 WDR5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
WDR5 NCOA6 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
KMT2D RBBP5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
LHX4 YY1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ASH2L KMT2B â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
HOXC8 MEOX2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
ASH2L KDM6A â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
KDM6A KMT2D â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KDM6A PAXIP1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ASH2L KMT2D â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
NKX2-5 TBX5 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
FBXW7 MYC â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
WDR82 WDR5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 20516061 23870121 27705803
WDR5 WDR82 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DPY30 ASH2L â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8153045 21516116
KMT2B RBBP5 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
ASH2L WDR82 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
HIST3H3 WDR5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ASH2L KMT2C â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HIST1H3A WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
KMT2B WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
KMT2C RBBP5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DPY30 WDR5 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
KMT2C WDR5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
KDM6A RBBP5 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
DPY30 RBBP5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KMT2D WDR5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
FOXI1 PAX8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15459102 15188428 12538519 15604103
MLL2 ASH2L â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 ASH2L â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
MLL2 WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
GATA3 H3C2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
KMT2D H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19219072 18022353
KMT2B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19219072 18022353
KDM6A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24561908 17713478 20123895
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR ZBTB16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15334066 20610535 16637071
AR KLF5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19460858 20610535
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ELK3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 7958835 15548518 23063436 15684718
ETS1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9349499 8262053 1722028
ETS1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145208 19022222 8649821 10510472
MYC ETS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18586674 12695333
FBXW7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15498494 17145710 32047362 28007894 31569395 33821962 20399964 20970423 17157259 16023596 20852628 15103331 15150404
SPI1 FLI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10523830 9858537 23056458
FLI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8510925 20110178 21205096 12724402
FLI1 GATA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12556498 12724402 16189514 10364157
SRF FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9315625 10742173 8864058 8986626 19581295 9690619 10777594 11846562 12242287 2104799 17938209 9111305 8007980 12760745 11862715 1902475 8423791 10642500 10330504 10961986 9032300 2511007 8164681 7854423 17182846 2200737 9271374 10369679 8413226 19173292 9349499 1630900 8262053 10319327 7910456 9545312 9571041 9734357 8764983 12231642 2493627 14693367 18557893 7588632
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
SPI1 GATA1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 10734131 10753833 12803886 16283355 16418395 20510871
SPI1 GATA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14559995 10411939 11023493 11001896 20304827
GATA1 GATA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19114560 12432220 20670937 14695898 21853041
GATA1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24336126 19522008 12832487
GATA1 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 10411939 10753833 15676205 10364157 12202480
GATA2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19522008 22951020
GATA2 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19620289 16254139 19491391 24583263
GATA2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18522800 19772889 15896659
GATA2 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10411939 10364157 18250304
GATA3 YY1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
GATA3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18522800 15632071 15896659
NKX2-5 GATA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19479054 15653675 16137232
HNF1B HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15486044 1363228 16793932 15001636
HNF4A HNF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8367288 9111350 9792724 8674436 11717395 9313764 9837989 9204893 9232592 1734282 20850486 8735941 11145965 11085951 10331424 8808405 12601360 16670373
HNF1A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
HNF1B HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10518495 8290348 11585914 16479257
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
IRF8 MYC â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10734131 11672593 11875494 11964313 12032143 12417340 12811837 16243976 16413922 16597464 17404308 17485448 22461508 23390297 24091328
SPI1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10570299 9593745 10734131 17386941 11483597 17200120
KLF4 PPARG â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10432118 10925299 12193690 21093321 21670502 23390297 6357187
KLF4 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18511453 16244670 17308127 21132436 17659301
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
MYC MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 1850105 7970710 19723804 12101422
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
ZBTB16 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14645547 19723763 19444914 18246121
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
PAX7 MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18854138 15501225 17548510 18508329
SRF MYOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17377068 8744946 9658178 23406902
MYOD1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 7970718 10373569 10601020 10801445 16936743 12665587 20053773
NFIA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12145335 10505791 10634504 8816507
NFIB NFIC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9099724 25258084 16189514
PAXIP1 PAX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10908331 17925232
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SMARCA4 SOX10 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 10757804 16373334 17325040 23874858
TEAD1 SOX10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11394999 28852375 14664827 22492709 12056842 21411665 27288457
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066