Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PCNA CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GRB2 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
ABL1 KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11753601 9916993
ANXA1 NFKBIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
KLF3 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRK ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
KMT2B ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
FYN ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIN1 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17828269
HNF4A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17885207
CRK KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK THOC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIN1 CSNK2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11940573 5215253
GRB2 ELK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ELK3 NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ESR1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10935492 12878732
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 HOXC6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21683083 18414489
ESR1 SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21820658 23192982
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
KMT2B FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
FYN NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
PRMT5 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PRMT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 KHSRP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 HNRNPF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
HNF4A SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12763030 22190905
MEN1 HOXC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14992727
NCOA6 KDM6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0810100105 19047629
YY1 KDM6A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
KLF3 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
KMT2A RELB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19219072
SMAD3 KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ZNF512B KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NCK1 KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCOA6 KMT2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17021013 0607313103
KMT2B TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
KMT2B TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
KMT2B TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
KMT2B RELB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19219072
KMT2D RELB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19219072
MYB TK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1944282
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
MYC TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
MYC TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
MYC SCARB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
SMAD3 NCOA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53BP1 NCOA6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
NCOA6 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19433796 0902873106
SMAD3 TRIM63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24438338 24920680
SMAD3 SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20123992 21965288
SMN1 SMARCB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TOPBP1 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
YY1 TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
ZNF512B YES1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
ASH2L HIST2H3C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
DPY30 HIST2H3C â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HIST2H3C PSIP1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
KMT2C NCOA6 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HIST2H3C RBBP5 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
P4HA3 DISC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC WDR82 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
P4HA3 PEX14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HIST2H3C TP53BP1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST2H3C KMT2C â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
HIST2H3C KMT2A â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
ASH2L MEN1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
KDM6A DPY30 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29785026 17178841 24981860
DPY30 MEN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23508102 17500065 24981860
SMAD3 MEN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 11274402
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ASH2L HCFC2 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MEN1 WDR5 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ESR1 AKAP8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33731348 31527615 21182205
ESR1 ASH2L â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16603732 21502505 31527615
CRK NCK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9837978 8879209
ESR1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16603732 21502505 31527615
HNF4A NCOA6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18552123 15604093 35140242 21292004
WDR5 KMT2D â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
KMT2A MYB â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HIST1H3A PRMT5 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
ASH2L PAXIP1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
HCFC2 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23508102 24981860 15199122
MEN1 RBBP5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17050672 24981860 14992727 23508102 15199122
WDR5 PAXIP1 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 24981860
HIST1H3A HIST2H3C â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MYC AKAP8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 17314511
WDR82 ASH2L â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 23508102 23870121 20516061 31076518
NCOA6 DPY30 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19047629 17500065 24981860
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
NCOA6 WDR5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PCNA TP53BP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
NCOA6 RBBP5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 NCOA6 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
NCOA6 ASH2L â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 17178841 24981860 12482968 23870121 23508102 17500065 19047629 17925232 19433796 34079125
PAXIP1 WDR5 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HIST1H3A KMT2A â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
KDM6A ASH2L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20305087 17178841 24981860 17761849 23508102 29785026 17825402 31076518 34079125
MEN1 ASH2L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17050672 24981860 14992727 23508102 15199122
NCOA6 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10866662 26487511 10681503 10567404 16794079 11773444
KDM6A NCOA6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MEN1 PSIP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22327296 18598942 23508102
WDR82 RBBP5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 23508102 23870121 20516061 31076518
ASH2L NCOA6 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
KDM6A KMT2C â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
GRB7 KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SEPTIN8 KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
YES1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16787943 11847100 16076903
KMT2B ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KMT2B ANXA7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KMT2B ATP1B1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CRK RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
MYC DPY30 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
RAP1B GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
RAP1B KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PIN1 KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NREP KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
WDR5 KMT2B â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
RCC1 KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 KMT2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KMT2B RPP14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KMT2B TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KMT2B SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KMT2C TSC22D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SMAD3 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15086314 23161884 16619037
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
MYC PEX14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
PIN1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21685363 21988832 19920136 19122240
YY1 WDR82 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
KDM6A WDR5 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
RBBP5 WDR82 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
WDR5 NCOA6 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
KMT2D RBBP5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
ASH2L KMT2B â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ASH2L KDM6A â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
DPY30 KMT2A â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
KDM6A KMT2D â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
KDM6A PAXIP1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ASH2L KMT2D â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
HCFC2 WDR5 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
WDR82 WDR5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 20516061 23870121 27705803
KMT2A PSIP1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CDKN1A PCNA â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
PAXIP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
WDR5 KMT2A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
WDR5 WDR82 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DPY30 ASH2L â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8153045 21516116
KMT2B RBBP5 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
NCK1 ABL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12379115 7926767 10372803 11494134 10967110 17474147
ASH2L WDR82 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ASH2L KMT2C â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HIST1H3A WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
KMT2B WDR5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
KMT2C RBBP5 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DPY30 WDR5 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
KMT2C WDR5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ASH2L KMT2A â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A WDR5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KMT2A RBBP5 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PRMT5 WDR77 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KDM6A RBBP5 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DPY30 RBBP5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
KMT2D WDR5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
TOPBP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RBBP5 WDR5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
CDKN1A PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 67.0 1.0 Omnipath 23443559 25411249 20606006 8868473 15576034 16474839 25416956 20605778 16510448 18703516 23139781 11302688 11254741 26272819 16616141 21988832 11313979 7780738 17588519 12964161 25502805 10022118 8861913 16189514 26496610 16082198 8861969 17129767 18263614 26186194 22383522 22911014 7915843 7911228 27107012 23223023 17115032 32296183 19895794 18794347 19704162 10873631 9546435 8662825 31515488 21415862 9545252 11350925 12930846
PRMT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22231400 20084102 15670829
KMT2D H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19219072 18022353
KMT2B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19219072 18022353
KDM6A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24561908 17713478 20123895
KMT2A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12453419 20210320 24680668 29897600 31485071 20541251 24235145 20452361
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
ABL1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14757045 20841568 12167702
ABL1 NCK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10372803 23331499 22327338 11494134 10967110 12379115 17474147 20841568 7926767
ABL1 PSTPIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11163214 20841568
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
ASH2L WDR5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L WDR5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ASH2L RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
SMAD3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10878024 9618481 14755691 10601254 16819512 17516505 10506225 14647420 14583455
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
SMAD3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 9618481 17550342 12545156 11013220 15155580 11074002
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 25814554 35044719 19380743
CSNK2A1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10783893 16007147 9721103 11673497 12138192 10723127 7796813 8657113 8622692 10421793 12167702 12403772 8668171 8657102 10398585 8601309 9214631
CSNK2A1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22184066 23226345
CSNK2A1 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11522824 7735324 11313925
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
RBBP5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
RBBP5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 DPY30 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
ESR1 RELB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17369819 20034404 19433448
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
KMT2D ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16603732
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
NCK1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
KLF8 MMP9 â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
KMT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20677832 16510874
MYC MMP9 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
MYC RCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9178906 14519204 9792927 12695333
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
TP53BP1 PAXIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19414588 15456759 17690115 14576432 19481982
PAXIP1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14576432 15456759 19481982 19414588
WDR5 RBBP5 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
WDR5 RBBP5 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 11302744 12874027 17168535 19407509
TP53BP1 ANXA1 â—¼   KO_UP_REGULATES ✅ + 1.21 1.21 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368