Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PRMT1 SHLD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CNOT8 BTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HIST1H4A HIST1H4C â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H4C HIST4H4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H4C HIST2H4A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST1H4A HIST2H4A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HIST2H4A HIST4H4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
COIL NTAQ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
AR MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 7657701
KDM1A CEP162 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CEP162 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1209814109 23071334
H4C6 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16628214 5218530
H4C6 MBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 14610093 10471499
H4C6 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 SIRT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18485871 23897426
H4C6 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18079182 11448779
H4C6 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4C6 SIRT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15469825 18485871
H4C6 PRMT5 â—¼   METHYLATION ✅ 2.0 0.8 intact 1209814109 23071334
PARP1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
NCOA2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
NCOA1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
NCOA3 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
PSMD2 ADRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
ADRM1 PSMD2 â—¼   COLOCALIZATION 2.0 0.8 intact 16990800 5219132
ALYREF AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18562279 0802533105
NR4A1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11274386 16835233
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
SIRT1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21775285
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
AKT1 RPS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20605787
NCOA2 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12588987 5216126
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
HNF4A AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474850 12466965
AR HNRNPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535
AR FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11690559 20610535
AR PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 20610535
AR CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16492776 16344550
AR DNM1L â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10454563 21724752
AR KHDRBS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18273831 20610535
HNRNPK AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18413735
EZH2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 23239736
AR CFLAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15731171
PRMT1 ARPC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TRAF6 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906941106 19955404
SH3GL1 AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FXR1 AXIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SMAD6 BMPR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12857866 12519765
YY1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21666725
EZH2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23624935 21406404
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
MBD2 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23011797 16052033
ELAVL1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19010922
BTF3 RPL24 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MBD2 C1QBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HABP4 C1QBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7041060 19523114
C1QBP COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
KDM1A C4ORF17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT1 C4ORF17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
FXR1 CAPRIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
NRIP1 CARM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219239 17053781
SPAG8 CARM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CARM1 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
CARM1 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6803829 19101556
NCOA1 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14966289 15988012
NR1H4 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15471871 16819395
EP300 CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 24229708 15138260
CBFB PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18316480 26010396
MYC CFLAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15367674 11359904
CFLAR DAXX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14637155
RELA CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
STAT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19061877
CIRBP HABP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8194383 21771594
PRMT5 CLK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
FXR1 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
PRMT1 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SCYL1 COIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HABP4 COIL â—¼   COLOCALIZATION 2.0 0.8 intact 7041060 19523114
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A2 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10938077
CUL3 HSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768582
USP7 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6799761 18566590
MAP3K5 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11003656 5213028
PRMT1 DAXX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DAXX TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 14557665 5216762
DHX9 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
PABPC1 EIF4A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0914856107 20133758
MYC EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18593934
HNRNPK ELAVL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
ELAVL1 SIRT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17317627
KLF1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1017029108 21670263
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
MED31 ERH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 ERH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
IGSF21 ERH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
VPS72 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EWSR1 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
EWSR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8164678 11423975
EWSR1 EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19502792 19289832
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
PRMT1 FAM83D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
PRMT1 FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 FXR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FXR1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 HABP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8194383 21771594
FXR1 GRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 KHDRBS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 HNRNPUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 KHDRBS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HNRNPU GAS7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217863 16055720
IGF2BP1 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19887615
PIAS1 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20711444
GPATCH2L KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT1 GPATCH2L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
GRIP1 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17476305 5219902
PRMT1 HABP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM HABP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
HDAC1 KLF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15542849 11287616
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
THRB HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16862226 18239067
HIF1A NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14729605
HIF1A KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
STAT1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19646959
STUB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19940151 25637186
PARP1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18314489
HIST1H4A HIST4H4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NR5A2 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069850 10799577
TP53 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8200620 21821029
PABPC1 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SYNCRIP HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK RALY â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
HNRNPK PRMT1 â—¼   METHYLATION ✅ 2.0 0.8 intact 6803829 19101556
HNRNPK MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8349701
RPL26 HNRNPR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRMT1 HNRNPR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HNRNPU TAF15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MED31 HNRNPUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
IDH3B PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
STAT1 IFNAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9121453 6730748
IGSF21 S100A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
IGSF21 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZNF451 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
TERF1 KDM1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KDM1A SAMD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RELA KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19208907 23423566
RALY KHDRBS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
KHDRBS1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KLF1 KLF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18687676
LARP4B PABPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20573744
ZMYM5 LRRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 SH3GL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22998870
MECOM YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1119229109 22308434
MECOM PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RUNX1 MECOM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22689058
MED31 SUPT5H â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MED31 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
MYCN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20145147
NCOA3 NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17476305 5219902
NCOA1 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10612426 23547260
RELA NCOA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16456540 5218295
PRMT1 NOL4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NR1H4 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11518759 11030331
PRMT1 NRIP1 â—¼   METHYLATION ✅ 2.0 0.8 intact 5219239 17053781
PARP1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPARA PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
STAT1 PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24242046
RELA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10542237 16189514
RIF1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
WDFY3 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RUNX1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18316480 26010396
ZMYM5 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT1 ZNF451 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT1 WDR33 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRMT1 VPS72 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT1 SAMD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT1 SPAG8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT1 YLPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRMT1 S100A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRMT5 SPAG8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RIF1 PSMD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PSMD2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMD2 PSMD4 â—¼   COLOCALIZATION 2.0 0.8 intact 16990800 5219132
PSMD4 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS3 RELA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24457201
RELA STAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
RIF1 S100A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SYNCRIP RPL24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 S100A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
USP7 SKP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19680264
THRB STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10976919
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
WDR77 THOC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
VIM TNFRSF14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TRAF6 TNIK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001376 22904686
TP53 WDR33 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 ZDHHC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28775165
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
ASH2L HIST1H4C â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ASH2L HIST2H4A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ASH2L HIST4H4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
ASH2L HIST1H4A â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
METTL14 METTL3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
BTF3 RPL26 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CNOT8 PUM1 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
DAXX HIST2H4A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
DAXX HIST1H4A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
LRRK2 STUB1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
RELA RPS3 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
FXR1 UBAP2L â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
HIST2H4A PRMT5 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
HIST1H4A PRMT5 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
CUL1 CARM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34480022 21145461
NTAQ1 AXIN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 ADRM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24947832
VCAM1 ARPC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
BRCA1 ASH2L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 26831064
BRCA1 KDM1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 26831064
BRCA1 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 CNBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
VCAM1 CNBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ESR1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
KLF8 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21416054 35140242
MYC CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
CTBP1 EZH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27634302 31041561
CUL3 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 21145461
DGCR8 MOV10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DGCR8 RALY â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 DHX9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 19805454 21182205 20348541
EP300 KLF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
SKP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 23770852
FLII ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14966289 19720835
ESR1 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 MOV10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
VCAM1 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
TDRD3 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 18632687
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
MYC IDH3B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
VCAM1 ILF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
LRRK2 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
MYC WDFY3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC RBM15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29467282
MYC NXF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RNPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC PSMD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
NCOA1 NCOA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17476305 18267973
NCOA3 NCOA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11971985 18267973
VCAM1 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RALY â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
KHDRBS1 LYN â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HIST1H4C WDR77 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST2H4A WDR77 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST1H4A WDR77 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
HIST4H4 WDR77 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
FUS SYNCRIP â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
BRCA1 TERF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 29656893 34112789
BRCA1 TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 25184681 29656893 34112789
FXR1 C1QBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29395067 32877691 21653829
RUNX1 CBFB â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 17431401 5219852
CLK3 CLK2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 8153045 21516116
GAN CUL3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15983046 31944090 21145461
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
NR1H4 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25675114 17333335
ESR1 KDM1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17289570 23403292 31527615
ESR1 MBD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 20300195
KDM1A EZH2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31130994 23455924
FUS RALY â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 30354839
MYC PSMD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
FUS PRMT1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HNF4A NCOA2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
HNF4A NCOA1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
AKT1 BRCA1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CARM1 RELA â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MAP3K5 DAXX â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 19789335
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DGCR8 ERH â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ESR1 NCOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 0.83 0.83 Signor 11477071
NCOA1 NCOA2 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
NCOA2 NR1H4 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
DHX9 NXF1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
LARP4B PABPC1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
TRAF6 USP7 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
PARP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 34079125 26831064 25252691
BRCA1 NCOA3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14578343 16860316
BRCA1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23624935 25531315
ESR1 CIRBP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
EP300 ILF3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 20808282
ESR1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
EZH2 MYCN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23362253 27728805
MYC HIF1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15071503 28205554 28628118
HNF4A NR1I2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15331348 16455805
KHDRBS1 HNRNPA1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24514149
HIST1H3A HIST2H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST4H4 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
HIST1H3A HIST1H4A â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
DAXX HDAC1 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HNRNPR PRMT1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
ESR1 ASH2L â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16603732 21502505 31527615
CAND1 SKP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12504026 29499133 21145461
CFTR FLII â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CLK3 RNPS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 32707033 32296183
FUS DHX9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16917507 14752096
ESR1 GRIP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17545996 9773983 17932106
TDRD3 FXR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18664458 29395067 24778252 24981860
NCOA3 NR4A1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12082103 16713569
CARM1 PABPC1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HNRNPK KHDRBS1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RPS3 SERBP1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
HDAC1 RUNX1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
HIST1H3A PRMT5 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
FUS HNRNPR â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
HIST1H3A HIST1H4A â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
MED31 POLR2G â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
THOC1 CHTOP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23299939 26496610
ESR1 DNM1L â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21217774 19805454
ESR1 STAT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 25303530
PARP1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19470756 34079125 16204234 20596014
TRAF6 PSMD2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
RNPS1 WDR33 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 17353931
ELAVL1 HNRNPK â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
RPL24 RPL26 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CUL1 FBXO7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HIF1A CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23401859 27320910 18323857 17439941 17132228 19940151
PSMD4 ADRM1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24429290 16990800 24121268 33961781 24811749 16815440 26186194 28514442
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
BRCA1 MRE11A â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CHTOP NXF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23299939 22658674
CLK2 RNPS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 32296183
CLK2 WDR33 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 23602568
KDM1A CTBP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17967884 20547759 16079794 26496610 16140033 26186194 28514442 28947780 31041561
CTBP1 NOL4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25416956 35016035 26186194 24722188 28514442
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
PIAS1 ESR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31527615 11117529 15666801
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC KDM1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 23455924 32296183 29467282
NR5A2 NCOA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15604093 22504882 23975195
PARK2 PSMD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MRE11A TERF2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AR STUB1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PIAS1 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CFTR STUB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
DAXX MAP3K5 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ALYREF THOC1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
LRRK2 MBP â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CTBP1 NRIP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
KHDRBS1 KHDRBS3 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
AKT1 NR4A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 16713569 11274386
CTBP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11751867 10196224 16713569 21102443 31636387
BRCA1 NCOA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11085509 14578343 16860316
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
CNOT8 BTG2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25416956 11136725
CFTR PSMD2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29924966 17110338 31324722
SMAD6 CTBP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24850914 14645520
FUS EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33742100 30110629 18509338
EP300 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18797151 9407140 10336495
NCOA1 NR4A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12082103 16713569 16002533
NRIP1 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9626662 10022764 16189514
AR EP300 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CLK2 CLK3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CARM1 NCOA3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CARM1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CTBP1 KDM1A â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HNRNPU SYNCRIP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
PIAS1 STAT1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
HNRNPA1 HNRNPR â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CIRBP HNRNPK â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ESR1 NRIP1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BTG1 CNOT8 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
STAT1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10792030 16713569
HDAC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10220405 21102443 16713569
C1QBP KLF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
NCOA3 CARM1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18511550 17043108 26267537 15383283 16938873 16923966
ERH CHTOP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 25284789 25416956 30021884
ILF3 DHX9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12946349 22751105 22939629 23986595 31536960
EP300 NR4A1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12082103 21988832 16713569 20438716
ILF3 FUS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29884807 27460707 11438536 16713569
MYC SKP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12963825 29467282 30415952 21988832 17314511
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
HIST1H3A KDM1A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NCOA1 THRB â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
DAXX TP53 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AR NCOA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
BMPR2 SMURF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12151385 12857866 11278251
AR BTG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 16281084
TUBA1A BTG1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BTG1 PRMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8663146 11856371 14734530
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
AKT1 HNRNPA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18562319
AKT1 SCYL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24769208
NCOA3 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10965917 17108143 19305643
AR NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21273442 20610535 23689136
AR PIAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 18656483 10628744
AR KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 16079795 22052438
AR CFLAR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16720717 15731171 20610535
RELA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16713569 8798655
AXIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19131971 20399964
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
DHX9 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12592385 9662397 26831064 16713569
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
BRCA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EZH2 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19079346 20574448
ESR1 BTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19117054
CUL3 CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 21249194 22013077 16449638 22405651 26286618 12609982
CAND1 SKP1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
NCOA3 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 22977234 15988012
NCOA2 CARM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14966289 16344550 15988012
HDAC1 CBFB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
MECOM CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11328817 11313276 16713569
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
LRRK2 DNM1L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24282027 22228096 22639965 23813973 29541021
MYC EIF4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
NCOA3 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18484708 20181721 19491275 10490106 25728767 26166704 12554772 18645020 16923966 16331275 16713569 11376110 21182203 23403292 11050174 9192892 26487511 28844863 11353774 15145444 17158759 11389589 14966289 9346901 26153859 17646391 20392877 15383283 12630920 9765300 12714702 14766010 30418174
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9259327 10409727 23874500 11014206 15604093 12554772 16282588 9427757 11113179 18451880 9121466 10598586 16713569 11165056 14715875 11376110 9774463 10760302 20608937 9192892 11003650 26487511 11867769 10454579 12574227 17363140 9773983 10731636 11358671 11250900 11682626 23975195 17627277 16606617 12630920 12714702 9192902 12738788 16957778 15140878
NRIP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9115274 26153859 8887632 16439465 26166704 9192902 21182203 23403292 33731348 7641693
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
GADD45A FAM83D â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FBXO7 SKP1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8090761 10029407
MYC FXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
GADD45A TP53 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A IGSF21 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GADD45A VIM â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MBD2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10444591 33961781 10471499 12183469 12665568 27173435 24981860 21258344 17634443 26496610 11102443 23752268 28514442 11297506 27593931
HIF1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 16511565 21148070 11641274 17273746
RUNX1 HDAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18316480 10617663 22777353
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
MYCN HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
HNF4A VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16568083 12750294 19671543
TP53 HNRNPR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TP53 HNRNPUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
HNRNPUL1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15907477
MYC KLF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
LYN STAT5A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9837784 22509308 8861946
MED31 NR4A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
STAT5A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17927978 12048235 12967477
MYC SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC ZNF451 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC RPL26 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 11085504
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
NR1H4 NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14698205 11136553 18391212 20338915 14684751
NR1I2 NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15331348 16455805 12072427 17429319 19171678 18096694 23602807 23160820 15604093 12909012
STAT1 NR1H4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19393742
NR1H4 NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16682417 21476904
RELA NR4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20018891
RELA PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20054868 10542237
PRMT1 TAF15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19124016 15782174
STAT1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16481475
USF1 SERBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18234320
SH3GL1 VIM â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
HIST4H4 PRMT5 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HNF4A HIF1A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 12097158 14741200
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
EP300 HIST1H3A â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
ESR1 NCOA3 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
DAXX HIST4H4 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NCOA2 NR5A2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
DHX9 PABPC1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
EIF4ENIF1 LSM14A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
RPL26 SERBP1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
HIST1H3A HIST1H4C â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
AKT1 MAP3K5 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
CARM1 HIST1H3A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
NCOA2 THRB â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
RPL24 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL26 RPS3 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CUL1 FBXL17 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
ADRM1 PSMA2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
HIF1A EP300 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 18268343 15154850 12914934 19074848 25192544 22789427 20829524 21148070 17502379 26826385 22075993 16543236 19680224 20603618 19589782 11063749 23618863 26135796 27808477 22219185 15155277 11823643 17906695 19666581 21187066 16189267 8917528 23746844 19940151 19071119 26944191 15261140 24421387 20000859 12778114 14691445 12042299 22684029 12588875 17382325 23966271 15342390 22735262 27320910 26751287 24821806 23448368 11959990 15280364 11940656 19696166 20620956 16081065 22908229 18047470 16847340 22807441 23880760
NCOA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12837248 17697320 11014206 12554772 18499756 15657427 11265755 9430642 11376110 9774463 16645043 9192892 11937504 26487511 12612084 19460354 20348541 11250900 12630920 12714702 14766010
HDAC1 KDM1A â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
DAXX HIST1H4C â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
HIST1H4C PRMT5 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
AR NCOA2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
AR NCOA3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 PPARA â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR1H4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
FBXL17 SKP1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
PSMD4 PSMD2 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 16990800 24256120 25036637 24121268 26344197 22939629 30479383 17646385 22863883
NCOA1 NR1I2 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL24 RPL26 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
PRMT5 WDR77 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
POLR2G SUPT5H â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
RPL24 RPS3 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
ESR1 NCOA2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
ADRM1 PSMD2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ADRM1 PSMD4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EIF4A3 MAGOH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
HDAC1 MBD2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CBFB RUNX1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA2 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA2 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMD2 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RELA CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
CUL2 HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
KDM1A H4C6 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
NR5A2 H4C6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
H4C6 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H4C6 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
PRMT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19234465 29227283 15670829 20951943 23071334
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
RELA AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20186924 18031796 20649564
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
STAT5A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24218138 24469394 18042802 20385773
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 CLK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20682768
AKT1 VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20856200
AKT1 NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10938135 17088940 16093479 16613989 11467847 7791761
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 ALYREF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18562279
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 25581517 11274386 16223362 17570479 16713569 26155943 18669648
AKT1 ILF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20870937 18097023
AKT1 CFLAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19339247
AKT1 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 16532036 14500571 11154276 30677014 17184578
AKT1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17428466 20832017 20085797 21242970 17570479 10542266
RELA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24466341 16619263 14576180 15517885 14715080
ESR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8299561 11000528 22391641
NCOA1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15514032 12163482 23145053 11673464
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
AR VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12020745 20610535 14684616 18451309
AR BTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21172304 20610535 16281084
AR FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14521927 21055159 20610535
NCOA2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9717843 12588987 15684378 14593076 24239470 15563469 18780293 12810069 16713569 10601285 14966121 10935543 10454556
BRCA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11085509 16713569 11016951
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
NRIP1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9368054 16527872
KDM1A AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17277772 16079795
EP300 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11971970 10779504 24480624 17011549 16713569
DAXX AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 27671201 17145710 15350595 15572661
NCOA3 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14966121 11747336 15563469 16713569 10965917 21047772
AR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12389206 11032808 16713569 11000528 18988627
CSNK2A2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877451
KLF8 AXIN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYC AXIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
KLF8 AXIN1 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYC AXIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
KLF8 AXIN1 â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 16288291 16940750 17143292 17306568 17666529 17671186 17936032 19619488 19623618 19751508 20006983 20705860 21151179 21285352 22270359 22290435 22761862 23343194 24023259 25730849 7542250 8666229
BRCA1 PARP1 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 PARP1 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
CTBP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20818429 21681822 23303449
TP53 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 9582019 11295099 18625847 11003642 12802282 16357511 14710355 9619832 19882681 10884389 11384963 11782367 12024039 15735697 12170778 21245169 17993233 12549011 11431698 16229810 18208621 10597265 21742769
BRCA1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20160719 18851829 9000507 21407215
BRCA1 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17428466 11777930 10962562 18025037 18350249 12647291
BRCA1 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 12771027 9346961 10779360 11877377 10367887 19004803 21060331 12496474 19793801 15650754 10962562 21337561 9892649 10528224 15459660 20029420
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
TP53 BTG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10321740 15741235 19031424 19551855 21394211 16581545
TP53 BTG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8944033 10669755
BTG2 PRMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11856371 16782888 8663146 16713569
SKP1 CAND1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 26632597 21463634 12504026 12609982 23535662 21863050
ESR1 CARM1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 14631847 12498683 11010967 14675539
CARM1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15731352 21988832 11997499 11701890 15616592 16923966 18280497
CBFB RUNX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25678665 11179217 14729951 24522927 23333304 20195544 17431401 14752096 11276260 2845103 15331439 10856244 11742995 26598521 22498736
RIPK1 CFLAR â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
CFLAR DAXX â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
RIPK1 CFLAR â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
CFLAR DAXX â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
RIPK1 CFLAR â—¼   ENZYMATIC_REACTION ✅ 48.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19498109 19524512 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22421439 22427918 23010170 23069999 23073834 23377657 23850759 24366341 24378531 26024392 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 9217161 9488730 9759866
CFLAR DAXX â—¼   ENZYMATIC_REACTION ✅ 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
MYC CFLAR â—¼   DOWN_REGULATES ✅ - 19.0 1.0 ACSN 11274345 11283613 11283614 11359904 11704864 15367674 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
RELA CFLAR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19343319 18073330 18222423 15986355 15723831
MYC CFLAR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15367674 22266862 11896589 20348907
CFLAR RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12887920 11002417 17047155 10837247
CSNK2A2 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 19651622 19415658 17081983 20166139 18767875 11602581 20068231 18452278 17570479 17287340 19413330 18669648
CSNK2A2 KLF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9722526
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
CTBP1 NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 24722188 11509661 18374649 17085477 16713569 15060175
RIPK1 DAXX â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
RIPK1 DAXX â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
RIPK1 DAXX â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
DAXX TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12954772 21482821 21134643 16845383 25241761 15364927 16713569 12482984 15339933 23038753
DAXX MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23331499 9743501 15258908 25241761 21071413 19789334 15983381 11003656 11495919 27488634
ELAVL1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18519672 19574298
ELAVL1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18680106 12963828 18519672
STAT1 EP300 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15731352 20448036 10490106 9920895
EP300 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 14726487 15509516 9989503 9773981 26504087
EP300 NR4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21988832 20438716 12082103 16713569
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
KDM1A ESR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17277772 24371278 19098913 18187655
NR5A2 ESR1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
STAT5A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11731618 22201800 11682624 11682625
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 NRIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20200160 10379892 16391242 22071320 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ESR1 PSMD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18457947 9253789 12648521 11696545 23580568
ESR1 NR5A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23911789 19376833 16091743
NRIP1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 9192902 23331499 8887632 9115274 7641693 26166704 12554755 26153859 21182203 16439465
PIAS1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15666801 11117529
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
ESR1 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18499756 9192892 9430642 11014206 19460354 15657427 23331499 11477071 26487511 16645043 12612084 20348541 12630920 14766010 17697320 11937504 12714702 12554772 9774463
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
STAT1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16494848 23086340 19556344
HIF1A FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19492421 16399861 17536272 17942638
RELA FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10649441 18064631 10867646 22223884 12372417
MYC FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 14519204 11896591 8376401 10421838
PRMT1 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 30354839 23152885 25192599 12183049 11850402 16169070 16713569 25810899
MYC GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15721278 9190899 10913183 15021909 14519204 9811446 21835778
TP53 GADD45A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10749144 22801474 11221850 15031557 22262183 10321740 17700520 11420680 10094833 23114628 8892753 23948959 9405685 21394211 9931282 10435630 12007564 15721278 17440969 23576563 9566896 9233781 21836608 21245169 15186775 17063488 9154806 10327059 9191059 17344317 9519881 20797428 18350249 7624148 10566557 17084916 16714289 20840860 15735726 12806965 18225552 16581545
TP53 GADD45A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16990795 15603758 14627995
HDAC1 GLI1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 14673164 15465827 21234400 21685935 22796940
GLI1 MYCN â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 11001584 11960000 12138125 14555646 15087129 15520176 16054035 16158046 16328026 16396903 16406505 16571352 16880536 17000779 17035233 17638910 18754008 18813803 19081070 19190345 19219074 19736394 20107231 21059263 21442356 22354771 23031257
HDAC1 GLI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20081843 21234400
MECOM HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11552981 23858473 16713569 11568182
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
RELA HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18498249 17898080 23185316
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
TP53 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11818510 16895524
HNF4A NR1I2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12774017 15331348 12601364 18305375
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
HNF4A PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11981036 15912134 19933841 17022998
MYC HNRNPA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12747840 20010808 12695333
HNRNPK KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21988832 22365833 31413325 16713569 12370808
HNRNPK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18472002 16360036 23092970
IFNAR1 STAT1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11698286 11964292 12811837 14610620 14764699 15864272 17513775 19833085 21115385 21840487 21930765 21930769 7512720 7521688 7543512
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
MBD2 KDM1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23000163 21452283 24163373 23928305 19738071
KDM1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17805299 26334721 19381457
PRMT1 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10748127 12529443 16713569 15782174
PIAS1 KLF8 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 15117942 16127449 19218564 20711444
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
LYN STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11413148 17081983 7925280 11641791 9573010 15212693 8617237
RIPK1 MAP3K5 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
RIPK1 MAP3K5 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRAF6 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18292600 9774977 10523862 10921914 17724081 15310755
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
ZBTB14 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10936031 10080939 9092617 9618270 8367294
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
MYCN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20811720 11107122 10050884 21862876 20145147 19885598
NCOA2 NCOA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11387316 12815072 10334992 16908160 11870371 10334993 16541101
NCOA1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11698662 10731636 9626662 12163133 21775429 15888456 9407140
NR5A2 NCOA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15986123 17463000 23723241 15345050 21445275 24973012 17666587 11103799
NR4A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23071566 17139261
PRMT1 NRIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17053781
NRIP1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 23331499 10022764 9626662 16189514 9774688
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
PIAS1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 11709556 29145629 23331499 12171910 25241761 14699505 12855578 11257227 18566411 17371985 23663276 9724754 10805787 18988627 19136629 18031232
PIAS1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 15133049 10380882 20805487 11867732 16713569 11583632 11788578
PPARA VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10377075 16115476 17434475 11459775 18755353 11007963
PRMT1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11257227 12171910
SKP1 RELA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
RELA SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20617556 15152190 24064732
RELA VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10833420 20966071 16317091 7536741 16627481 16385502 10946302 19422386 22708120 23042817 19281832 10553096 10329958 11359843 7692229 16249517 10496926 7537851 16453001
SIRT1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19408108 25217963 15152190 21081649
STAT1 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
S100A8 TRAF6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 18070982 15247281 21220427 12140561 12138165 8837778 19592497 18347055
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
STAT1 STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066
TP53 FGF2 â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368