Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NSD2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
NSD2 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
H2AX SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
H2AX H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
H2AX DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
ATM H2AX â—¼   COLOCALIZATION 2.0 0.8 intact 16858402 5218840
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
RIF1 CPE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BRCA1 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9008167 19146767
H4C6 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
SUMO2 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
H3-4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 HSPB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
H3-4 POLR3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 MRE11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16774833
RIF1 COX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 COX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MRE11 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
MRE11 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RAD50 MRE11 â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
PRMT1 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15741314
CDKN2C SNU13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 SNU13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 SNU13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GRB2 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
H3C2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
H3C2 XRCC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
KAT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10096020
GRB2 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
SUMO2 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
H4C6 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16628214 5218530
H4C6 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
H4C6 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H4C6 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18079182 11448779
RIF1 AKR1C3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 ANKRD24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 ARL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ASF1A EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19270680
RIF1 ATF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
ATM RRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19015526 0803313105
ATM HERC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20023648
RIF1 ATP1B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
LRRK2 AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ESR1 BLM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17268063
RIF1 BOC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YY1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21666725
EP300 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353771 23285190
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
PIAS4 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21113239
RIF1 BRMS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CBX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 CCDC106 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CCDC106 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CDKN2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CETN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LRRK2 CETN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
RIF1 CKMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM CRCT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 CRCT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 CTBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20176810 20098713
RIF1 CTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KAT5 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
HERC2 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
MDC1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
UBE2N DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
TP53BP1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
RAD50 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
RNF168 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
RIF1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
UBE2V2 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
RNF8 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
NBN DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
PAXIP1 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
PIAS4 DCLRE1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25512557 15574327
LRRK2 DDIT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
RIF1 DDIT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HMOX2 DOT1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
NBN EP300 â—¼   COLOCALIZATION 2.0 0.8 intact 21108945 8058069
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
RIF1 ETHE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 FAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YY1 FAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18495079
RIF1 FXR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FXR1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
RIF1 GC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SMARCD1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ITGB3BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 PPP1CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
RIF1 GSTM4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HERC2 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RIF1 HLA-DQA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 HMGB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 HMOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPB1 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 POLR3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18950704
RIF1 HSPB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 HSPBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 HSPE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPE1 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LRRK2 ITGB3BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
RIF1 ITGB3BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ZNF24 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
KAT5 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 MAD2L1BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 POLR3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT5 TK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 PLEKHA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM KIF20B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RIF1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 KLK10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 LAMA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 LAMA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 LAMTOR5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LRRK2 LATS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
RIF1 MAD2L1BP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MEN1 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
RIF1 MLLT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 MNAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2V2 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 MOB4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 MPHOSPH6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 MRPS12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 MRPS6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 NACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NANOG TDGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16846370 20549704
NBN SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RAD50 NBN â—¼   COLOCALIZATION 2.0 0.8 intact 7114538 19197236
RIF1 NRBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PAEP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 PAEP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PAFAH1B3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PCDHA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PDCD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PFDN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RPLP1 PFDN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PFN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPP1CA PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22479341
XRCC6 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
SMARCD1 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUMO2 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
XRCC5 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
PIAS4 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
RIF1 PLEKHA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PNP TGIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RIF1 PNP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 POLR2C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 POLR3F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PQBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PRMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRMT1 S100A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PSG9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PSMD11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 PSMD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PSPC1 RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 RAB27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 RAD50 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RIF1 RBM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 RFC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SNRPN RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RPA2 RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VDAC3 RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
VDAC1 RIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RIF1 ZNF24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 WDR62 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 TRDMT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 UBE2V2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 RPLP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 SULT1E1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 SERPINB9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 SELENBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 RIT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 TGIF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 S100A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 TK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 RPL37A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 TSPAN6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 WWC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 SPG7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 TDGF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 RNF10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 VIM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 SMN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 STX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 RRM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 TMSB4X â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SUMO2 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
RNF8 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20385750
RPA2 RPLP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 RPLP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RPLP1 SAT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
XRCC6 SERPINB9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SIRT3 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18710944
XRCC6 SMPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VIM SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBE2N SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO2 TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
SUMO2 UBE2V2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22661230 22635276
TOPBP1 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
VIM TP53BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YY1 TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
VDAC3 VDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BLM RPA2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
PSMD11 PSMD2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDC5L PPP1CA â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
APEX1 EP300 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
RAD50 ATM â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 18854157
ATM RAD50 â—¼   PHOSPHORYLATION 0.8 0.8 Signor 17570479
INCENP KIF22 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RAD50 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ + 0.8 0.8 Signor 10426999
MRE11 H2AX â—¼   COLOCALIZATION ✅ 0.81 0.81 mint 22157895 8303386
SUMO2 MDC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 32786267 19471022 22661230 19394292
SUMO2 RIF1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29234018 19471022 32786267 21252943 21693764
CDK7 POLR2C â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
PPP1CA RIF1 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
APEX1 NSD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28986522 34079125
CTBP1 H2AX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34133714 31041561
H2AX RAD50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15201865 31501894 16377563 10959836 18583988 19234442
MYC PP1G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
PP1G PQBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 30344098
DDX1 RFA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 24332808
RFA2 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 20711169
TP53B XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22990118 29656893
MYC PP1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
NBN TE2IP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 34079125
RIF1 TE2IP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12753906 34079125
TE2IP MDC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15383534 34079125
TE2IP XRCC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15383534 15100233
DDX1 MRE11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 18710941
MRE11 NBN â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
PKHA4 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31091453 16169070
CTBP1 BASI â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31041561 34709727
BASI CDC42 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34709727
BASI RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
S15A1 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
S39A9 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TMM9B RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BRCA1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 34079125
ESR1 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
XRCC6 APEX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30585729 34079125
APEX1 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28986522 34079125
ASF1B RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC CBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CDC5L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CDCA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
ESR1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
MYC CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
MYC DDX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
ESR1 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21182205
ESR1 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 VDAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
ESR1 FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 19805454
ESR1 NACA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
LRRK2 HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24725412 29519959
KAT5 PDCD5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 19308289
LRRK2 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
LRRK2 VDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 21370995
LRRK2 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
MYC RAD50 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC RFC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC XRCC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
PIAS4 RIF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29234018 15383276
NBN TERF2IP â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ATM MDC1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12607003
MDC1 RNF10 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
NSD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24101509 31527615
H2AX XRCC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20085707 21679440 18406329
RFA2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26344197 10064605 24981860 24332808
ATM RFA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10713094 9725899
EP300 TP53B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16051665 29656893
MYC TP53B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29656893 29467282 20195357
PP1A CDCA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BRCA1 TE2IP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 34112789 29656893 34079125
BASI ATM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CBX1 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
H3C2 CBX1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
RPA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 11953755
MYC HSPB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
MYC PSMD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
ATM NBN â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 10802669
BRCA1 UBE2N â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
BLM RAD50 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
BLM H2AX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15364958 29523790
TP53B RAD50 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20010693 29656893
TP53B RIF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29234018 29203878 29656893
SUMO2 BLM â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19471022 16524884 16620772 21693764
EP300 XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21988832 15023334 33742100
ESR1 PSPC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 PQBP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
GRB2 HSPB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31980649 12577067
PIAS4 SUMO2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
H2AX XRCC6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15613478 33961781 23145133 20224553 28514442 18406329
RFA2 CDK7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26344197 29568061 24332808
RAD50 BLM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25084169 10783165 29523790
BLM MYC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30415952 29467282 23750012
SUMO2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21147198 20016594 20016603 22689573 21693764
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
EP300 RAD50 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16051665 20808282
RNF8 NBN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26869104 18001825 23115235
MDC1 TOPBP1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
MDC1 SMARCD1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
H2AX NBN â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 6805208 18583988
NBN H2AX â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 22157895 8303386
H2AX NBN â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 22565321 8391733
BRCA1 PP1G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17511879 30344098
TP53B NBN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20010693 29656893 20081839
NBN BLM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10783165 29523790
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
ATM H2AX â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18344987 26095369 21704408 22451927 11893489 20081839 16858402 9488723 22184063 11571274 21676867 32518374 27918549
PP1G PP1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26344197 30344098 24366813 28514442
BLM RFA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24332808 12724401 24126761 28506294 30279242 15775963
PP1A PP1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 26344197 22939629 26496610 26186194 28514442 29669786
TE2IP MRE11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15383534 22939629 15100233
VDAC1 BASI â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31536960 34709727 29128334
TP53BP1 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 16415788 5218238
H4C6 TP53BP1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 16415788 5218238
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
RNF8 HERC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22508508 20023648 22814251 26503038 25305019
POT1 TERF2IP â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ASF1A H4C6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
BRCA1 MYC â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
BRCA1 MDC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RAD50 TERF2IP â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ATM BRCA1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 NBN â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RNF168 TP53BP1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ASF1A ASF1B â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
H2AX MRE11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12419185 15201865 31501894 16377563 22157895 18583988 19234442
PP1G CDCA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27880917 30344098 28330616 26186194 24366813 28514442
TP53B RFA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15856006 29656893
ATM MRE11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10783165 15758953 10608806
MRE11 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10783165 28506294 29523790
ASF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
H3C2 ASF1A â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 7219095 19498464
H3C2 ASF1A â—¼   PROXIMITY ✅ 0.88 0.88 mint 25281560
AMOT LATS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24255178 32292505 24101513 24366813 30266805 34079125
ESR1 ASF1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 31527615
ATM BLM â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BRCA1 BLM â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25084169 29656893 26831064 10783165
BLM RIF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23509288 20711169
CTBP1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11751867 10196224 16713569 21102443 31636387
CDK7 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10949034 31527615 15461668
NBN EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16051665 21108945
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NSD2 MDC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31248990 21293379
TP53B H2AX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21566653 12697768 21317870 28242625 18001825 17024177 15364958 20075863 21623170 12607005 18001824 26734725 31009828 12447390 29662616 29499138
PP1G RIF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27880917 30344098 28330616 26496610 26186194 24366813 23080069 28514442 21382349
RFA2 MEN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12509449 16189514
BLM TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15364958 17984114 29656893
MDC1 TP53B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18986980 30179224 29656893 12607005 17925396
TP53B BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22884692 17525332 21552324 29656893 12364621 31009828 18001824 26831064
PP1B RIF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28330616 27173435 26496610
MRE11 XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30585729 10508516 26344197
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
MDC1 ATM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29656893 26734725 12607005 14519663 18006705 28943310
MDC1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21622030 17525332 15569676 29656893 12607005 19766185 12611903
NBN BRCA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10426999 29656893 10783165 11504724 25659039 25939603 25184681 19244116 18171670 12124328
TGIF1 CTBP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25910212 20361981 10995736 16713569 25416956 16189514
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
UBE2N RNF8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22589545 31048496 20023648 16215985 22814251 23255131 28244869 25909880 19549727 21706008 26285145 18678647 24732096 31792955 27909234 21911360 29523790
VDAC1 VDAC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30021884 31536960 22939629 29128334
MDC1 TOPBP1 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
ERCC6 VIM â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
PPP1CC RIF1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
MDC1 RAD50 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
DOT1L MLLT3 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
MDC1 H2AX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21622030 21293379 15201865 20159462 18001825 28242625 26734725 16377563 12607005 18001824 14519663 30598506 18583988 32518374 12475977 21676867 19234442 29499138
NBN H2AX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16932743 12419185 11110662 15201865 18001825 31501894 20081839 23145133 16377563 18001824 22157895 18583988 22941933 21676867 15733840
H2AX BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18344987 12419185 26095369 20681793 19805520 18001825 31501894 26121674 10959836 12485996 18001824 19766185 11927591 34321665 29499138
UBE2N H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17709392 18077395
PP1G PP1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 30344098 28330616 26496610 26186194 24366813 28514442
ATM TP53B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12697768 29656893 20081839 22621922 12447390 11042216 20010693 18996087
CDC5L PP1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11101529 22940584 10827081 20467437
BRCA1 PP1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12438214 22990118 17511879 25056273
PP1A RIF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 27880917 15231748 28330616 22321011 26186194 28514442
TE2IP RAD50 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 22939629 15100233
TE2IP XRCC6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383534 21044950 26496610 15100233 34079125
RPA2 MRE11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
MDC1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12607003 30179224 29656893 20081839 12607005 14519663 18583988
BRCA1 MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10426999 11353843 17349954 23530059 24413181 16391231 29656893 11504724 25184681 10783165
NBN MRE11 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12750284 12419185 24413181 21884979 24981860 22939629 12679336 10426999 28369484 17526493 9705271 26455393 12607003 17612497 12447395 22464731 22078559 22231403 34348893 28363998 11062235 15758953 11238951 23530059 33558481 15734743 34038735 30179224 12861053 18458108 19270065 17500065 10783165 30440001 22941933 19244116
ASF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
H3C2 ASF1B â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 7219095 19498464
H3C2 ASF1B â—¼   PROXIMITY ✅ 0.9 0.9 mint 25281560
ASF1B H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11985607 12842904
ERCC6 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11003660 16772382
EP300 APEX1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20856196 19934257 14633989 30110629 20808282
RPA2 ATM â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
KAT5 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16141325
MYC BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11916966 9788437 20215511 30415952 16713569 12646176 14612409
ESR1 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11493692 27977889 10334989 11782371 16713569 17505062 15674350 19887647 20060929 11244506 16860316 17392432 31527615 16061635 16260778 12400015 1244506 25499220 29367421
EP300 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10655477 21212407 19887647 22787115 16713569 11782371 21102443
BRCA1 ESR1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MYC EP400 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 18413597 21150319 29467282 30415952 20946988 17314511 11509179
EP400 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20351180 14966270
ESR1 PRMT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28539435 18657504 11029009
MYC FXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
GRB2 TEK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11191051 7478529 10521483
MAPK6 HDAC11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ITGB3BP MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RPA2 KAT5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
MYC KLK10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
RPA2 MAD2L2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15254543 16819516 15199127
PPP1R7 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 WWC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 SPG7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RNF8 MDC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24240613 25512560 18001825 26734725 18001824 18006705 28943310
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
TK1 MKI67 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MKI67 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
MYC PQBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PPP1R7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
NBN RPA2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
TK1 NRBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PIAS4 RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20016603
RPA2 RAD50 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18171670 11080452 17965729
TMSB4X SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 TMSB4X â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
RNF8 UBE2N â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MNAT1 POLR2C â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
ATM NBN â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
MDC1 NBN â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
H2AX KAT5 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 23777805 20224553 18406329
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
PP1G ESR1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 17274640 31527615
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
NBN RAD50 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
BLM PAXIP1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
PAXIP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EP400 KAT5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
BLM TP53BP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
ASF1B ASF1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 24981860 22407294 26496610 12842904 34079125
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
MDC1 MAPK6 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
PPP1CC PPP1R7 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PPP1CB PPP1R7 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
PPP1CA PPP1R7 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
H2AX MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6805208 18583988
NBN MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20224574 7891431
RAD50 NBN â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 19197236 22939629 12679336 10426999 26344197 17526493 9705271 12607003 17612497 12447395 22464731 34348893 11062235 15758953 12124328 11238951 26215093 23530059 15734743 16391231 24651726 30179224 17500065 30440001 22941933 10783165
MRPS12 MRPS6 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
RAD50 MRE11 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12750284 24413181 24981860 19197236 22939629 31501894 30733337 10508516 26344197 8756642 28369484 9705271 26455393 12607003 16163361 11504724 34348893 28363998 11062235 26215093 27173435 23530059 33558481 15734743 16391231 24651726 17694070 34038735 17500065 19270065 30179224 10888888 10783165
TOPBP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL37A RPLP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMD11 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NSD2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
NSD2 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NSD2 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
NSD2 XRCC5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H2AX ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
H2AX PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H2AX RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
BRCA1 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18001824 18001825 17145710 12419185
ATM H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 197.0 1.0 Omnipath 27410735 28544233 16426903 28797244 9488723 23847653 30197789 21930799 18158901 21693595 18848500 22819196 15603757 16760673 17570479 24688021 24793032 27458206 16531125 22028490 30154456 19230794 23202908 25852739 19059218 26073471 22247744 28259974 29584802 25691887 19049966 20368801 26700820 29386061 28124509 20613862 27550454 20847938 27388041 27752097 23269287 24480460 22237206 20461094 20971043 26941327 18285803 21690091 15279774 23891287 25847270 24490130 25349305 26906421 20637859 26314960 15286739 27780918 20454618 30013081 28671946 25218945 23742011 26391293 23972723 23382699 26416514 27442013 20703100 24726884 26512707 27332952 29641431 25287622 26295265 14643438 29163809 25264544 19895790 26504743 26113859 27431324 28790385 18413980 21283714 21787120 20205745 19781914 25093845 27135971 23227178 22224778 20923785 20860841 24244154 23386996 30065307 16858402 11879731 28009280 23343929 20192759 22761798 26855420 24378750 20068231 20580718 14504478 24893124 29048667 25661368 26860083 26019182 20488183 28764946 22205726 23977391 18471973 19591958 28239143 20542002 17525332 20495376 18755145 23050241 17782711 11571274 19473884 28431265 25742493 18248856 17690115 20684759 26317467 21727091 24651472 25827888 27164092 28587922 20976184 30723510 20471486 23772364 29794999 11893489 19014481 20165693 26671524 16997395 20936109 26114388 23845989 15138496 22761813 23355489 27455285 28943310 21348461 19647519 23678292 23166506 28099474 29434792 25249630 25269479 27310012 15177039 22559321 26045162 20865059 22972376 21148072 26760771 21188122 22962268 22768044 26711340 20460517 27845910 28855246
RNF8 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19772495 7575488 18590585 17303408 18001824 18678890 18583988 18001825 18678709 12607003 9407949 17660363 18006705 15279786 15459660
RNF168 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19342239 22980979 31533041 18443409
H2AX TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17145710 20075863 18001824 21317870 12447390 17024177 18001825 21566653 12607005 12697768 21623170
H2AX MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21676867 14519663 18001824 21293379 16427009 16377563 18583988 21622030 18001825 12607005 19234442 20159462 15201865
MRE11 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
NBN H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
XRCC6 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H3-4 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
H3-4 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H3-4 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H3-4 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
CBX1 H3-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19111658 16127177 18438399
XRCC5 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MRE11 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MRE11 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MRE11 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MRE11 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19709933 26240375 17570479 31353207 10608806
RAD50 MRE11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19197236 16163361 10888888 8756642 17713585
MRE11 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 22464731 26455393 12861053 17500065 15734743 12419185 19270065 22078559 19244116 21884979 12679336 11238951 12607003 9705271 17713585 10783165 12447395 10426999 18458108 15758953
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
ASF1B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11985607 17353931 15664198 27753532 12842904
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
CBX1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15136563 11882902 16622419 20871592 11242053 19111658 15960974 16415788 26527279
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
ASF1A H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15664198 10759893 11985607
XRCC5 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
NBN H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
XRCC6 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H4C6 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H4C6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
H4C6 MIS18BP1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 20080577 19410545 17199038 19398759 16622420 21768289 19410544 19410539 20566683
H4C6 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
H4C6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
ASF1A H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11985607 15664198 25416956 32296183 10759893
KAT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12776177 10096020 32814053 24525235 16844118
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
H4C6 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23760478 25579814 23377543 25651062 17190600 27153538 18296440 22373579 19218832 16415788
RPA2 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
MYC APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14519204 11983916 12695333 11085504
EP300 APEX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14633989 20856196 20711647
BLM ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
XRCC6 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
BRCA1 ATM â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
XRCC5 ATM â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
ATM RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATM RAD50 â—¼   PHYSICAL_INTERACTION 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
ATM MDC1 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM RAD50 â—¼   SHARES_COMPLEX 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM RPA2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDC1 â—¼   ENZYMATIC_REACTION ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM BRCA1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM RAD50 â—¼   REGULATES ✅ 100.0 1.0 ACSN 11283614 11331603 11850621 11877377 12086603 12202749 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
ATM MDC1 â—¼   REGULATES ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
AURKB ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22099307 27493659
PAXIP1 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15456759 19414588 17690115
ATM RIF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18077418 15342490
ATM RPA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 29875999 15964794 11877377 17303408 9725899 16163361 14872059 23847781 9139719 10713094 9295339 20860841 16731533 12607003 22977173 7171818 15459660
ATM NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 12433983 12861053 17485521 23146902 10839545 19413330 15302935 27602502 17429352 19523210 24360018 20068231 17507690 17570479 10608806 12598907 18669648 25088203 18003706 11252893 17431132 23097684 10766245 12814430 10802669 21664921 26512707 10839544 11927276 21130714 17525332 12447395 14707289 15733840 15279770 25119968 18644472 28822740
ATM DCLRE1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15723659 25842165 15574327 15456891 16874298 15468306
ATM BLM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16199871 11146546 25766002 17984114 14643436 20719863 17363339 14729972 18054789 12034743 30496191 16880735 11375976
ATM MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28193847 21705321 22234877 12607003 12607005 22234878 17525332 18006705
ATM TOPBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11756551 18077418 19279141 17525332 17446169
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
ATM BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 26927092 17303408 15159397 24746700 12024016 10866324 30197789 12919958 11114888 26745677 26383678 34301763 12427729 11313470 16163361 28035057 20068231 25939603 26320175 17570479 19683496 22743550 10608806 23802008 23847781 21203981 15964794 12183412 12607003 17525332 19996295 15459660 11278964 19651622 21706030 11877377 20952512 10373534 19622773 10550055 27170701 15212693 23704879
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM RAD50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17570479 17081983 15302935
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 14762106 14722118 11895474 17081983 19007248 11420699 15676024 12458200 18669648
AURKB YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23226345
AURKB TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415769
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
BLM KAT5 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 22021381 16153896 18923075 18805091 21325134 22792074 19419957 21052091 18971343 25122754 11301010 21240188
BLM POT1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 16697054 18931676 19622404 19686080 19772495 19847258 22266823 22657828 23253856 24089143 24095737
BLM RAD50 â—¼   UP_REGULATES ✅ + 35.0 1.0 ACSN 12239151 12466554 12535671 12972610 14657033 14988723 15136767 15189446 16337602 16697054 17035102 18157158 18448394 18469862 18472307 18550849 18931676 19217833 19225445 19258535 19282663 19622404 19686080 19772495 19847258 20832754 21948210 22266823 22615860 22657828 23253856 23444773 24089143 24095737 8020957
BRCA1 RAD50 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 RAD50 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
MDC1 BRCA1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MYC BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12032322 19882681 20940401 10375022 21668996 11916966 12646176 11983916
CTBP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20818429 21681822 23303449
PPP1CA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 25056273 12438214 17511879 17603999
RAD50 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10783165 16260778 16391231 10426999 11504724 25084169 25184681 16713569
MDC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18087291 17525332 12607005
BRCA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11244506 12400015 15674350 10334989 16713569 11493692
RPA2 CDK7 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 MNAT1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 CDK7 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 MNAT1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
XRCC5 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
XRCC6 DCLRE1C â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11955432 16600297 16093244 16914548
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
EP300 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20471956 16051665 21108945
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
ESR1 SERPINB9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11682627 14617632
MNAT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10428798 10949034 12527756 16076840 8308015
YY1 FAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16784892 17530016 16143308 11418634
HERC2 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
HERC2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
HERC2 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
HERC2 XRCC5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
HERC2 RNF168 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20023648
HERC2 RNF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20023648 22508508 25305019 22814251
MYC HSPE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14519204 11983916 12695333
MYC ID2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12447693 12695333 12824180 18437010 18483244 12545167
RIF1 KAT5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PAXIP1 KAT5 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
RAD50 MDC1 â—¼   PHYSICAL_INTERACTION 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
XRCC5 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 MDC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MDC1 RNF8 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 12607003 15279786 15459660 15496928 15549137 15655342 17303408 17660363 18001824 18001825 18006705 18087291 18171670 18212739 18583988 18590585 18678709 18678890 18809224 19217833 19270065 19490890 19772495 20021983 20064462 7575488 9407949
MDC1 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
MDC1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RAD50 MDC1 â—¼   SHARES_COMPLEX 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
MDC1 RNF8 â—¼   ENZYMATIC_REACTION ✅ 27.0 1.0 ACSN 12607003 15279786 15459660 15496928 15549137 15655342 17303408 17660363 18001824 18001825 18006705 18087291 18171670 18212739 18583988 18590585 18678709 18678890 18809224 19217833 19270065 19490890 19772495 20021983 20064462 7575488 9407949
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MDC1 NBN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 15201865 20460517 23115235 14519663 18001824 18678890 19804756 18583988 19230643 12607003 12607005 20224574
MDC1 RNF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 24240613 18001824 25512560 18001825 18678647 18082599 18006705
RPA2 MNAT1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
RPA2 MNAT1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 11900249 12648680 12947387 15459660 15703371 16697054 17116885 17296725 17386261 17582221 17884153 18677104 19473888 19595721 19596235 19596236 19667075 19686080 19793801 19809470 19847258 20211143 21376743 22101340 22257761 22373527 22615860 22743550 22824526 23085398 24050180 7533895
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
NBN RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
NBN XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2V2 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RIF1 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RNF8 PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
UBE2N PAXIP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 PAXIP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 PAXIP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PAXIP1 PIAS4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
PAXIP1 RNF168 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
TP53BP1 PAXIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19414588 15456759 17690115 14576432 19481982
PAXIP1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14576432 15456759 19481982 19414588
RIF1 PIAS4 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RIF1 RAD50 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC5 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 RAD50 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
TP53BP1 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
XRCC6 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 RIF1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2N RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RNF8 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
UBE2V2 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
RIF1 RNF168 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
TP53BP1 RIF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15342490 23333305 29203878
XRCC6 RNF168 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 RNF168 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF8 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF8 TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 18001824 18006705 19203579 19772495
RNF8 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 20023648 21911360 22589545 25909880 16215985 24732096 18678647 26285145 23255131 22814251 19549727
RPA2 TOPBP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 TOPBP1 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
RPA2 TOPBP1 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
XRCC6 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 TP53BP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2N TP53BP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 17349954 17652783 18196958 19203579 19258535 19793861 19793862 19841479 19851286 22771115
XRCC5 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 UBE2V2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 UBE2V2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
RNF8 VIM â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
ERCC6 MAPK6 â—¼   KO_DOWN_REGULATES ✅ - -1.05 1.04 PKG 28854368
ATM SERPINB9 â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
MDC1 SERPINB9 â—¼   KO_UP_REGULATES ✅ + 1.23 1.23 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
CBX1 TMSB4X â—¼   KO_UP_REGULATES ✅ + 1.32 1.32 PKG 28854368
ERCC6 AKR1C3 â—¼   KO_DOWN_REGULATES ✅ - -1.54 1.53 PKG 28854368
MDC1 VIM â—¼   KO_UP_REGULATES ✅ + 2.11 2.11 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
ATM VIM â—¼   KO_DOWN_REGULATES ✅ - -2.44 2.43 PKG 28854368
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
NBN NBN â—¼   KO_DOWN_REGULATES ✅ - -6.31 6.3 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368