Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
G3BP1 CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217568 15743820
SRC CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16005629 15157149
FYN CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7524477 6730342
CSK G3BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 5217568 15743820
RUVBL1 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL2 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS9 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12049732 16691505
NFKB2 CAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ CAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CAD MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SRC ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
GRB10 ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
FGR ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ABI1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ABI1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
AHR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114727 16091746
GRB2 BAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAP2K1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15994315 15121878
HTT CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16777606 10770929
CASP3 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17899380
CASP7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP7 TNFRSF1A â—¼   COLOCALIZATION 2.0 0.8 intact 8095238 21157428
HSPA5 CASP7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11943137
CCNT1 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
CCNT2 NCBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10866664 7853496
YWHAZ DFFA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
DNAJC7 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
DNAJC7 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DUSP16 GABARAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GRB2 EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
HTT EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EEF2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MAP2K1 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10716983 10997882
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
ESR1 MAP3K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15556606 5217326
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
YWHAZ FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
FASN IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FASN MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FASN MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FASN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FASN NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FGR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10329689 23109003
SHC1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7516469 5220322
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN G3BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217568 15743820
G3BP1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GABARAP HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GART IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
GRB10 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 RPS9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 RUVBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RUVBL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TUBA4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
VAV1 GRB2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
PPP1CA HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17008050
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC6 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HDAC6 TUBA4A â—¼   COLOCALIZATION 2.0 0.8 intact 5215415 12024216
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
HDAC6 TUBA4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024216
VHL HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
HIF1A PPP5C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020
HIF1A SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20003295
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HSPA5 NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HTRA2 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKACA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KAT5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMARCB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP1CA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RIPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10880512 5212735
TUBA1A IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKG NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKG MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKG NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC IKBKG â—¼   COLOCALIZATION 2.0 0.8 intact 20970423 8045055
MAP3K3 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
IKBKG NFKBIE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
SP1 ILK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19176380 24361375
TRAF2 IRF7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15361868 19479062
KAT2A SOCS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19339690
LRRK2 LATS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LGALS3BP TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LGALS3BP TRADD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LGALS3BP MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ LIMK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215799 12361576
LIMK1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11276226 10559936
LRRK2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
LRRK2 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
MAD2L1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PRKACA MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20713600
SP1 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17889508 16452190
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
MAP2K1 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16251502
MAPK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16709866
MAP2K7 MAP3K1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11306453 9639556
TUBA1A MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPS9 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL2 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNFRSF1B MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12517920
MAP3K1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10085121
RUVBL2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAZ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP1CA MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SEC16A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP4K1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAP4K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1381507 8226933
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PRKCE MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11350735
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK1 METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33217317
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
PRKCE MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16810323 16461926
PPP1CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK3 METTL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33217317
MYC PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15197457 12420224
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
NCOA2 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19305643 10454563
NCOA2 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11923473 23936147
TUBA1A NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NFKBIE NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SP1 NFKB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7541912
VCP NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL2 NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RHOA OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20553488 7717051
VAV1 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
VAV1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
SP1 PRKCE â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24825907 18249093
PRKCZ VHL â—¼   COLOCALIZATION 2.0 0.8 intact 5219754 17350623
YWHAZ PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10620507
SRC PTPN23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18835089 8310575
SRC PTPN23 â—¼   COLOCALIZATION 2.0 0.8 intact 18835089 8310575
USP11 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL1 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMARCA4 RELB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RHOA VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511940 6743311
SRC RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10592173 23027962
RIN3 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RUVBL2 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL1 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RUVBL1 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 RUVBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RUVBL2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RUVBL2 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SMARCA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20129940 8009769
SMARCA4 VHL â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SP1 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20644166
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SP1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11133225 7499419
VAV1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1531699 1311423
SRC VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1531699 1311423
TRIM31 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YWHAZ TUBA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CCNT1 MYC â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
GRB2 MAP4K1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
ITGA4 YWHAZ â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
NEDD4 NTRK1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16701206 27445338 21332718 19953087 25921289
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
GRB2 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
LRRK2 ABCE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
SMARCB1 ACTL6A â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
LRRK2 DFFA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
PAK1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12374744 16452229
ESR1 KAT2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16260778 31527615
ESR2 NFKB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25604459 29509190
VCAM1 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HDAC6 G3BP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32082291 18079183 21532619
RIN3 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32552912 17474147
VCAM1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HTRA2 LATS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17130845 16007220 22641346
NEDD4 ISG15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18287095 18305167
LRRK2 RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21454543 31046837
MYC RRP1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
VCAM1 NAA15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 UBR4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
TUBA1A TUBA4A â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
TNFRSF1A TRAF2 â—¼   UP_REGULATES ✅ + 0.82 0.82 Signor 10795740
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
CFTR RAB5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26618866 19398555 21455491
TAF10 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31527615 7923369
PPP1CA RRP1B â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ESR1 NCOA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 0.83 0.83 Signor 11477071
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
HDAC1 SMAD2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
DERL1 CFTR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26618866 16954204 16901789 18555783
ESR1 RRP1B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
RAD9A HDAC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10846170 16189514
MYC HIF1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15071503 28205554 28628118
TRAF2 TAB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19150425 17384642 14633987 10882101
MAX TRRAP â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
RIPK1 TAB2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
SMARCA4 SP1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ESR2 NCOA2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
AHR NCOA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12024042 15641800
CFTR UBR4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
SMAD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11555647 20207742
SRC GRB10 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10871840 32814053 33961781
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
SMAD2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31130994 10199400 14699069 11226163
LATS2 LATS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24255178 21233212 32707033 34079125
LRRK2 PAK6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24510904 26375402 24947832
TAB2 TRAF2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
IKBKG MAP3K14 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
LIMK2 LIMK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9089416 8980133 33961781
ESR1 CCNT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 15940264
MAX KAT2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12660246 10611234
RIPK3 TRAF2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10339433 16713569
MAPK1 SHC1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
HDAC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
G3BP2 G3BP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26777405 24981860 29395067 26186194 28514442
SOCS1 GRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10022833 29991678
HDAC1 VHL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
TRAF2 HTRA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 33229071 31617661 20562859
MYC TAF12 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 35140242 12660246
G3BP1 G3BP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AHR ESR1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IKBKG IRAK1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MAP3K1 MAPK1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
SHC1 SRC â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
SRC ESR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11032808 12630920 15604093 11013076 12095943
SOCS1 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10022833 16713569 29991678
HDAC1 SMARCA4 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IKBKG TNFRSF1A â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IRAK1 IRF7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15767370 21903422
MAP1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21159966 24754922
TAF12 TAF9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23292512
TNFRSF1B TRAF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MAP3K14 TRAF2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ELK1 MAPK3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
IRAK1 TAB2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
KAT2A MYC â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ABCE1 NAA15 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MYC TRRAP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SHC1 CSK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10037694 19380743 12048194
YWHAZ BAD â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 1204662 8005727 11526496
TRRAP ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11931763 16260778 12837248 12738788 31527615
SRC FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16966330 31980649 28514442 19711372 9169421
NTRK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748052 11733534 25921289
TAB2 IRAK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23986494 24735611 18180283 12242293 11518704 19675569
MAP1LC3B NEDD4 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RHOA PKN3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 31871319
TRADD RIPK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23429285 30561431 21724995 27768232 8612133 16603398 24735611
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
GRB2 VAV1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
RELB MAP3K14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11239468 15140882 16303288
NFKB2 MAP3K14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11239468 15140882 16303288
PPP1CA CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 4092695
MAPK3 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21419341
MAPK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8929531 10597268 12566304
MAPK3 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19777442 10597268 12566304
BAP1 UBE2O â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34591877 33961781 19615732 24703950 32509391 27705803
CASP7 DFFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10318789
VCP DERL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 15215856
MYC ELK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SHC1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
SRC ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17043237 17284441 17400812 15604093 11032808 17921256 18451880 15020686 12736255 11564893 23065768 10454579 20935677 17363140 16957778 14963108 11013076 29720121 15784253 24498420 17627277 12630920 22328528 14766010 24051437 7539106 27420286 15140878
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
ESR1 RPS6KB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22286763 21292829 18414489
MYC FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14519204 12695333
PRKACA FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20658524
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
YWHAZ GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HIF1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24015760 16511565 21148070 11641274 17273746
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
HDAC1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10199400
MAPK6 HDAC11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HIF1A TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18178340 21176881
SP1 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22399227 20018729
TAB2 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21988832 23986494 17626013
SHC1 ILK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PAK1 LIMK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10652353 10559936 11340065
LIMK1 RHOA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11018042 16219803 10652353
PAK6 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25714010 26375402 28007610
PRKACA LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21390248 24351927
MAP1LC3B SMARCB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAP2K3 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8226933
MAPK3 MAP3K3 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
MAP3K3 MAPK1 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK3 PPP1CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
RHOA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10617617 9854026 12810709
MAPK3 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15930121
MAPK3 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14993270
SHC1 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 TUBA1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCZ MAPK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20538799 11158308
TRRAP MAX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9708738 20946988 29028833 12660246 10611234
SMAD2 MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 11804592 28628118
TRRAP MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12077335 17353931 21150319 32140074 16705173 9708738 29467282 11839798 30415952 20946988 17314511 11511539 19818711 12660246 10611234
MYC RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22159222 20383141 22235332
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
RELB NFKB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22864569 12505990 27609421 22388891 14743216 14678988 28514442 17962807
SP1 NTRK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19656944 19643914 21123453
RIPK3 RIPK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19524513 30420664 29497034 22864571 26786097 31358971 22817896 23744296 26559832 19524512 26319693 22265414 22265413 29352166 29883609 21903422 24098568 25882049 10339433
VAV1 SHC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9209406 8677749 7539782
SP1 TNFRSF1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22019592 8954938 22615874
SP1 TUBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9677424 9325332 8955122
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
TAF12 TAF10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 14580349 24981860 19114550 7729427 12601814 23292512 9603525
BAD YWHAZ â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
VCP DERL1 â—¼   PHYSICAL_INTERACTION ✅ + 0.9 0.9 Signor 15215856
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KAT5 RUVBL2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CSK SRC â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
TUBA4A TUBB3 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ABCE1 RPS9 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
TNFRSF1A TRADD â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ACTL6A KAT5 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
NEDD4 GRB10 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 12697834 10446181 15060076
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
IKBKG RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EIF5B RPS9 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
TNFRSF1A TRAF2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
KAT2A TAF10 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
ELK1 MAPK1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ACTL6A RUVBL2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
KAT5 RUVBL1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
TAF12 TRRAP â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
TAF10 KAT2A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 17643375 24981860 19114550 12601814 17375202 31753913 10373431
RHOA TUBA4A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ACTL6A RUVBL1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
PRKCE YWHAZ â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SMARCB1 SMARCA4 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
RUVBL2 TRRAP â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
KAT5 TRRAP â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SUPT3H TAF12 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
GRB10 NEDD4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
ACTL6A SMARCB1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
ACTL6A TRRAP â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
KAT2A SUPT3H â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
NCOA2 ESR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12837248 17697320 11014206 12554772 18499756 15657427 11265755 9430642 11376110 9774463 16645043 9192892 11937504 26487511 12612084 19460354 20348541 11250900 12630920 12714702 14766010
SRC SHC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9388490 18840094 9710204 10482988 9096689 7499252 8939605 26551075 16189514
KAT2A TRRAP â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
NTRK1 SHC1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
NFKB2 RELB â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DERL1 VCP â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TRADD TRAF2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TAF10 TRRAP â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
SUPT3H TRRAP â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
EEF2 RPS9 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
SUPT3H TAF10 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ESR1 NCOA2 â—¼   PHYSICAL_INTERACTION 989.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 12213123 8491186 8950973 9927207 9733714 8112292 10356320 11370743 32062451 8294403 16371368 22057045 9045692 9032244 8995379 7514169 9175774 9541596 8663178 7629070 9019162 7597091 7798267 9544989 9488479 8940013 10570290 15812354 11792427 8621719 24430869 7650032 11453982 16713569 7516467 10477741 8662733 11302736 26551075 9254595 7559490 12441060 8662998 8235613 12485888 28690151 16520382 8939605 11505033 9129019 11707405 15888547 8647288 7524086 25416956 24189400 11827484 12149229 8195171 21725358 9020193 10049786 9797459 9886492 33961781 9126968 8626525 7537740 12577067 11964172 12898421 8810340 22974441 19380743 9434624 10080542 9083103 21706016 15688026 7535773 31980649 8561895 7744881
RUVBL1 TRRAP â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
ACTL6A SMARCA4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMARCA4 SMARCB1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RUVBL1 RUVBL2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
MAX MYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TAF10 TAF12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
HIF1A VHL â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CSK SRC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 17192274 18268019 22677902 23691193 24030100 27452906
CSK FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
PRKACA CSK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9224730 11181701 20826718 31125786 12600271
CSK FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1985196 8262983 11489946 16537894 9647655 25720756 18691976 10366594 19369195 1533589 1699196 7524477 16713569 15713745 14967142
CSK FGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 11489946 7515063 16537894 8612628 14967142
CSK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12767520 12048194 18829532 9819392 19380743 10037694 17673906
CSK SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 55.0 1.0 Omnipath 11489946 23051580 20657842 20337577 7592628 23824743 21940449 26453921 22323292 14665621 17525734 14967142 3103926 23159740 16227616 1383688 12387813 20525307 10698938 7525268 19534553 16537894 26234813 10592173 12468645 7513429 24632723 7687537 21442427 22689825 25372749 11007774 9208935 18614016 28974561 21632985 19369195 17855352 7678701 23378895 9523754
TNFRSF1B MAP3K14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 7639698 25152365 19815541 8702708 7544915
RIPK1 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11116146 15047705
TRAF2 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9275204 11278268 23543740 18997792 20385093 25416956 15084608 10755617 16713569 9334169 25246529 20348096 20651737 20184394 9020361
MAP3K14 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16189514 9927690 14743216
MAP3K14 NFKB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 11239468 14743216 15994789 11687592 15140882
MYC CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 7739536 10931841 11673469 10657901 12177005 14519204 9111322 9811896 10567564 17706770 24771621 11983916
ESR1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16675542 12746293
SP1 CAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1346130 16675542 7905000 12746293
PRKACA CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 19651622 17081983 1359877 18767875 17322306 18691976 4092695 19664994 20068231 18707149 23429703 11986331 17206380 14991569 19664995 18669648 33771897
MAPK3 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17206380 25472841 12438317 15890648
RPS6KB1 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23429703 25061101
MAPK1 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10659854 12438317 15890648
MAPK1 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19917258 17855441 21419341 21900237
SP1 AHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9778040 16410262 21569840 20478378
AHR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12612060 17392787 10620335
PAK1 BAD â—¼   ENZYMATIC_REACTION ✅ 39.0 1.0 ACSN 10230394 10461188 10467124 10511705 10558990 10559936 10611223 10613909 10661401 10837486 11018042 11062502 11121431 11340065 11385609 11413130 11493700 11907067 11950587 12054568 12885870 12954615 14749719 14764585 15157156 15229651 15280015 15536084 15713627 16293614 16702231 17270021 17522712 22154077 8625410 8929531 9346240 9381178 9843499
PRKCE BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20179209 20566643
PPP1CA BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 10811615 17274640 22820751
RPS6KB1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15280015 10611223 12954615 9346240 11493700 10230394 10558990 8929531 9381178 19641507 17270021 10837486
PRKACA BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 11983683 10880354 20166139 9346240 11493700 9381178 18794113 12931191 15280015 10230394 10558990 8929531 18669648 10837473 10837486 10611223 12954615 10949026 10851172 15123689 18707149 16403219 17270021
PAK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 27121078 20166139 22096607 9346240 18823547 11493700 9381178 23650610 15280015 10230394 10558990 8929531 25225063 18669648 10837486 10611223 23109003 12954615 10949026 16413544 19465939 18707149 15784622 17270021
CASP3 DFFA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11406587 25241761 12655299 18723680 9786842 9422513 9422506 16189514 9108473 11752060
CASP7 TNFRSF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11755217 16189514
PRKACA CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 28003367 23060444 25867080 21455600 30600261 1716180 28242698 19328185 32102849 92316961 19095655 14602047 7530719 10581361 11053017 9385646 25330774 15657296 1377674
MYC DFFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 18500556
MAPK1 DUSP16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12794087 15689616 11359773 11489891
DUSP4 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 15315965 18988627 7535768
DUSP4 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 8626452 15315965 32296183 18988627 7535768
ELK1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 8386592 11145955 7588619 7889942
ELK1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 8386592 11145955 7588619 7889942
MAPK3 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 9130707 20506250 15547943 20371703 7618106 7601337 12697810 12473660 23331499 8007980 16291755 16393692 16998585 18988627 17255949 8208531 15014501 15187187 8586671 19541618 11145955 25241761 19565474 11309409 8887554 17052211 15277685 18334532 15782123 8548291 14499342 9927426 7889942 8262053 8386592 10716983 12665513 15967991 8477450 12947314 15212693 11274345
MAPK1 ELK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 17145710 9130707 20506250 15547943 12551925 19690332 9763608 12697810 8007980 16291755 11279280 16393692 17255949 8208531 15014501 10637505 15187187 8586671 19541618 11145955 19565474 11309409 8887554 17052211 9501095 18334532 15782123 8548291 9927426 21655091 7889942 8262053 15655247 8386592 10716983 12665513 15967991 10644696 8477450 12947314 11274345
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 RELB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17369819 20034404 19433448
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
PAK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 18521086 26944939 16778166 18755239 21893191 15178330 19205871 29548483 26554417 27003261 24505617 16452229 15193262 19557173 15642175 12374744 19465939 17604944 25447917 20179234
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
RPS6KB1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 29128895 23242584 22114931 23460185 19925796 19112174 7838153
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
ESR1 NCOA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18499756 9192892 9430642 11014206 19460354 15657427 23331499 11477071 26487511 16645043 12612084 20348541 12630920 14766010 17697320 11937504 12714702 12554772 9774463
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11013076 12095943 12630920 11032808
ITGA4 FYN â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
FYN VAV1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 12218089 12731048 15699036 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502 9822663
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SHC1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10871840 16713569
FYN VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11262396 15699036 11005864 9438848 16713569 15933714 9822663
FYN SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 96.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 16713569 9446569 17389395 23331499 18578522 10921922 10482988 10764799 18452278 20068231 10592173 18669648 12522270 9685404 10896916 7516469 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
MAPK1 GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15952796 18220336 18669648 20068231
SRC GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10871840
MAPK3 GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15952796 18669648 18220336
GRB10 NEDD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12697834 23331499 10446181
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 MAP3K1 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10086337 10465784 10567412 10811803 10982827 11274345 11447289 11668179 11777939 12040186 12048245 12175651 12419216 12640133 12738796 12782630 14585353 15170913 15567848 15574420 15863030 16102570 16227978 16488589 16582911 16887996 17496910 17496911 17673906 18855897 19449109 19568798 19615955 21102635 21614932 24027568 26552706 7510700 8551221 9379049 9582321
GRB2 MAP3K1 â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10086337 10465784 10567412 10811803 10982827 11274345 11447289 11668179 11777939 12040186 12048245 12175651 12419216 12640133 12738796 12782630 14585353 15170913 15567848 15574420 15863030 16102570 16227978 16488589 16582911 16887996 17496910 17496911 17673906 18855897 19449109 19568798 19615955 21102635 21614932 24027568 26552706 7510700 8551221 9379049 9582321
GRB2 VAV1 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10077632 10086337 10426994 10567412 10646608 10679059 10714681 10811803 10849438 10898494 10982827 11080163 11447289 11526404 11698448 11754814 11777939 11777960 11907067 11994416 12094222 12165654 12175651 12186560 12616499 12626562 12640133 12740575 12885870 12917349 14764585 15169881 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 8551221 9438848
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 ITGA4 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
VAV1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 8900182 10207103 9013873 15558030 7651724 7809090 8621483 29997244 18692475 7478592 16713569 11406576 9209406 16339550
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
GRB2 MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9346925 9891069 9788432 17474147 11279207
GRB2 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12522133
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
PRKACA HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22865920 20716686
MAPK3 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24089523
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
VHL HIF1A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10973499 11900249 12351678 12648680 12820959 15340381 15459660 15652751 15688063 15703371 15721254 16697054 17884153 18931676 18985005 19622404 19686080 19809470 19847258
HIF1A VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12205091 15930297 21887475 22150821 22396654 15962286 23159849 17482131 17140440 16883594
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
VHL HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 123.0 1.0 Omnipath 17145710 21332579 24857547 12682018 26496610 11292861 11024059 15060148 16278378 12586829 17353276 12004076 12205091 17339318 10823831 11226425 21602890 16862177 15611064 12351678 16140212 11865071 26037477 16611863 10973499 23401859 25361009 11331613 18305400 25438054 14691445 17047048 12538644 22932900 18985005 26735336 21358672 18323857 10878807 19147576 16511565 17973296 23413029 24316222 11986208 12808024 12464182 23318261 22369643 19940151 15721254 20724477 21335603 16391536 23387829 18694926 26743088 14556007 18264140 10353251 15082527 11358837 11292862 11566883 12050673 19123984 17558023 27281823 15805242 11641274 25500545 34174286 24899725 12606543 32535973 17132228 24015760 12086861 11504942 35589690 26215701 22351759 12925778 18222538 17986458 14600153 10944113 23580587 26611735 18426857 20049704
MAPK1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16954218 10551817 18519666 18687685 26784107
MAPK3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10551817 18519666 24099156
HTRA2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10521396 11583623 11803371 12815069 12835328 15781261 19935698 20125124 23070005
TAB2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
TRADD IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
RIPK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
MAP3K1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9008162 19666475 9689078 12221085
NFKBIE IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
IKBKG RELB â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
TRAF2 IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
RIPK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10880512 21383699 21458669 14653779 10980203 17702576 9927690 16603398 16547522 16965765 10755617
IRAK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11583588 21220427 18180283 17997719
TNFRSF1A IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 10755617
ILK SMAD2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11696562 15905178 24527345 25100717 25268583 27111285
PAK1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22521536 25738875 27642646 17420447
IRAK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15767370 17457343 21903422
IRAK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11518704 12242293 19675569 23331499 18180283 21071413 11259596
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
PRKACA ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21224395 20166139 18578522 23979717 31562188 18583710 18707149 17603879 19401330 12837751 11533025
KAT2A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11804596 19407812 15522869 12660246
KAT2A SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11058129 15009097
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
PAK1 LIMK1 â—¼   ENZYMATIC_REACTION ✅ 28.0 1.0 ACSN 10461188 10467124 10511705 10559936 10613909 10661401 11018042 11062502 11121431 11340065 11385609 11413130 11907067 11950587 12054568 12885870 14749719 14764585 15157156 15229651 15536084 15713627 16293614 16702231 17522712 22154077 8625410 9843499
PAK1 LIMK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 22154077 11784854 15660133 11413130 10559936 23550835 17522712 11018042 11950587 17981134 10592173 22458949 10613909 11340065 25721396 10461188 10652353
PAK1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 18593598 27542844 21371233 22105362 22981863 18668521 27169363 12876277 31416844 23331499 33789117 7873542 29551131 28225038 19595712 11435472 9351825 25794709 9416003 21248166 14993270 23701950 18940914 16129686 11948406 23162738
TRAF2 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18855897 11274345 21614932
MAP3K1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8385802 12048245 8131746 17110930 8034665 8019005 10969079 12456688
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
TRADD MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRAF2 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TNFRSF1A MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TAB2 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
PAK1 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10661401 11062502 11385609 11907067 12885870 14764585 15536084
RIPK1 MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1B MAP2K3 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
MAP3K3 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7839144 12761204 11971971 9162092
RIPK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
MAP3K1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7839144 17143273 11971971 9639556
PAK1 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7592586 11304531 15677464 11309380 14970210
TRAF2 MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
TRADD MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
TNFRSF1A MAP2K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
MAP3K1 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531 9379049 9582321
TNFRSF1A MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1B MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
RIPK1 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TRAF2 MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 11274345 12556535 12655147 12738796 15592525 17462996 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531
TRADD MAP2K7 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11274345 12556535 12655147 12738796 14730360 15592525 17462996 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050
TNFRSF1A MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
TRADD MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
MAP3K3 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18855897 11274345 21614932
RIPK1 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
TRAF2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12655147 21614932 12738796 11274345 18855897
MAP3K1 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 10713157 19392652 18855897 9379049 26696630 17462996 12947395 18641653 23331499 23850759 12048245 11668179 21133840 21614932 21232017 12738796 9582321 24378531 22903704 11242034 10465784 15592525 17110930 26192618 9312068 17496911 11274345 15170913
RIPK1 MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRADD MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TNFRSF1A MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
MAP3K1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531 9379049 9582321
TRADD MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
RIPK1 MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TNFRSF1A MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
MAP3K1 TNFRSF1B â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531 9379049 9582321
RIPK1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11369754
MAP4K1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8824585 23331499 9003777
PAK1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24699410 12228228
TRAF2 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10346818 17145710 25241761 16636664 10755617 18635759 25260751
MAP3K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10969079 15315965 17052767 12049732 11971971
MAP3K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 25241761 15315965 12049732 24135036
MAPK1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
SP1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12220517 16797880 20506264 20121399 20882567 18372343 10727414 21170990 17889508
PRKCZ MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
SHC1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10996427 23584453
VAV1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 8900182 9013873
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 12054624 15547943 20080742 14967450 12040186 15173823 12697810 11940578 7545671 16227978 21035469 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 19085255 11279232 9271440 18039929 18775330 11705993 10601235 12792650 11431469
MAPK1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 10197981 34504019 18775330 20659902 8226933 9620846 16156666 9604935 18988627 12193595 11027280 8388392 27153775 31995604
MAPK1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19604315 15542607 16964243 15212693 11604394
MAPK1 TNFRSF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10702263 11606045
MAPK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19318349 20882567 16377629 18775330 8226933 14744793 16079281 11904305 9604935 15212693 14593115 8388392
MAPK3 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10197981 16156666 27153775 29577978
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK3 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17081983 16156666 19413330 11027280 9620846 33676893 23331499 8226933 20068231 18988627 12193595 18491316 18691976 8388392 19651622 10197981 18775330 19115199 9604935 15212693
MAPK3 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 15547943 20080742 14967450 12040186 15173823 12697810 11940578 16227978 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 11279232 9271440 18039929 18775330 10601235 12792650 11431469
MAPK3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 18463697 9155018 21071413 32482868 18988627 15210690
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
PAK1 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 21372320 21177870 18720373 21317288 18248330 17161475
MAPK7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22046506 9461566
MYC MAX â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12040186 15121849 16908182 2006410 8425218
MYC MAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10508165 15665468 8385351 8649388 8521822 22384171 1406956 17341548
MAX MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 17145710 16287840 25609649 12821782 16606833 16596619 21807113 25522242 20691906 19578763 24951594 8224841 17643117 9528857 12391307 16705173 21150319 10229200 21988832 15572685 9680483 2006410 17314511 14749374 12553908 17289033 17418410 19623651 12824180 17157259 12584560 26496610 20946988 20936779 8425218 23816886 17353931 10319872 17471507 18003922 16140957 20382893 12660246 8266081 7565735 32296183 10465786 26267534 17072308 27705803 9184233 18620061 10918583 17700062 10593926 10611234 16352593 9708738
NCBP2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
MYC TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17848523 23775087 11511535 20194507
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
SMARCB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10319872 14559996 14964309 19234532
TRRAP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 17353931 11511539 12660246 20194507 9708738
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
NFKB2 RELB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 17145710 20126461 16551621 17072323 16970925 16793322 12709443 11687592 9681829 17962807 14743216 17254973 15218526 7925301 16108830 12927781 17561400 15371334 16285893 15145317 19098713 12505990 17548614 17072322
NTRK1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 8155326 9715270 8226808 15056278 10708759 8552402 9856458 23331499 10629055 10092678 12446789 8524391 25921289 7541035 8183561
SHC1 PAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
PRKACA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12654918 21572420 20591975 8599934 16109481 34088899 11162591 15890975
PRKACA YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 29109150 11956222 12861023 16376338 19451227
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
PRKCE SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 11834516 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCZ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 10527887 11447289 19615955 16488589 6321473 8321321 12845332 11313945 16189514 12040186 19568798 15567848 14585353
PRKCZ SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23148884 16943418 18258854 19464346 27320013 17049555 20953893
VAV1 RHOA â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
VAV1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 10849438 22952938 9695188 12626562 12917349 12165654 25539813 19909365 14757747 18511940 10077632 26552706 12885870 11526404 10898494 25355530 10592173 11698448 10646608 11994416 16397238 20189481 22513334 12616499 10679059 23109003 12740575 11754814 9438848 11080163 10714681 32203420 9601639 14764585 15169881 22786724 12094222 26192618 8189062 8226994 16887996 12186560
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 RIPK3 â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10521396 11003656 11274345 1134007 11583996 12215447 12702723 12724420 12887920 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18570872 18621737 18641653 19037093 19131965 19498109 19524512 19524513 19597341 19632174 19838173 19935698 20125124 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
RIPK1 TNFRSF1A â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
RIPK1 TRADD â—¼   PHYSICAL_INTERACTION 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TNFRSF1A â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
RIPK1 TRADD â—¼   SHARES_COMPLEX 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
RIPK1 RIPK3 â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10521396 11003656 11274345 1134007 11583996 12215447 12702723 12724420 12887920 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18570872 18621737 18641653 19037093 19131965 19498109 19524512 19524513 19597341 19632174 19838173 19935698 20125124 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TRADD â—¼   ENZYMATIC_REACTION ✅ 78.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 12887920 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 16713974 17301840 17462996 17496911 17560373 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19632174 19641494 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 8974401 9379049 9488730 9582321
RIPK1 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
RIPK1 RIPK3 â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10521396 11003656 11274345 1134007 11583996 12215447 12702723 12724420 12887920 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18570872 18621737 18641653 19037093 19131965 19498109 19524512 19524513 19597341 19632174 19838173 19935698 20125124 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
SOCS1 RIPK1 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10485906 12193701 12223527 12811837 21469115 23124025
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
TRADD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12887920 24735611 20203691 21724995 8612133 21741934 16603398 21119000
TNFRSF1A RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 25681446 11002422 20547836 8612133 18450452 27552911 26802121 10356400 19773432 18621737 23815148 16611992 22179575 12721308 21741934 7538908 18949366 21113135 8985253 10744744 10795740 21119000 22733818 10755617 27321185 15115707 24098568 18939944 18329793 20825417 20448643 15357952 21737329 12887920 24130170 15258597 24758719 16115877 19524513 18724939 16968706 22817896 28817177 18022363 19815541 25388546 21331078 22848449
RIPK3 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11734559 21903422 22265414 19524512 19524513 22817896 26559832 10339433 26319693 11585904 22265413
RIPK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15327770 16603398
SRC SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 19901323 9388490 8939605 9096689 10971656 16497976 15592455 9121430 10891441 17389395 11687594 10329689 10482988 20068231 17570479 16189514 9685404 23109003 7516469 9927207 18840094 15688026 15212693 1409579 14963047 9710204 26551075 17016520 11075717
SMAD2 SP1 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19558215 10878024 12631740 11013220 11114293
SMARCB1 SMARCA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 10078207 18414052 23540691 20506188 8895581 31759698
SRC VAV1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17686471 8986718 11007481 10395673 9099726
TRADD TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRADD TNFRSF1A â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRADD TNFRSF1A â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRADD TNFRSF1A â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TNFRSF1A TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 26212014 8565075 8943045 8612133 16713569 16611992 22179575 11821416 7544915 12721308 21741934 10795740 21119000 19150425 27321185 25241761 15115707 18776134 15743837 15485837 20448643 12887920 24735611 20333651 18022363 19815541
TNFRSF1A TRADD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 72.0 1.0 Omnipath 17145710 8565075 8943045 11934887 8612133 9915703 11684708 8621670 9430227 19641494 27552911 16611992 21760970 11821416 10187805 21724995 12721308 21741934 21232017 10795740 21119000 15310755 11502070 15115707 23955153 18776134 18939944 9916731 9129204 9082980 15485837 15173123 22297296 15357952 24130170 12887920 10634209 24758719 19524513 15465831 7758105 11035039 8791485 15725726
TRAF2 TNFRSF1B â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23070005 23850759 24378531 9379049 9582321
TRAF2 TNFRSF1B â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23070005 23850759 24378531 9379049 9582321
TNFRSF1B TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8702708 10206649 16713569 8069916 7544915 18161752 14743216 9162022 15572357 18671942 9461607 8855313 11907088 8710854 11112773 15485837 9168896 8548810 7639698
TRAF2 TRADD â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321
TRAF2 TRADD â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10465784 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11668179 11875494 12048245 12556535 12646658 12655147 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15592525 15699106 16713974 17301840 17462996 17496911 17916596 18264787 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21614932 21826665 22955274 23010170 23070005 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 28765050 8910423 9379049 9488730 9582321
TRADD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 8702708 8565075 14585074 16713569 27383048 18621737 14743216 12796506 21741934 11181075 21119000 10911999 20203691 10892748 23955153 11112773 18439848 32296183 15485837 12887920 12517920 19815541 11479302 9020361